ID A0A2C9M0P9_BIOGL Unreviewed; 249 AA.
AC A0A2C9M0P9;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Nuclear transcription factor Y subunit beta {ECO:0000256|ARBA:ARBA00015277};
DE AltName: Full=CAAT box DNA-binding protein subunit B {ECO:0000256|ARBA:ARBA00029965};
DE AltName: Full=Nuclear transcription factor Y subunit B {ECO:0000256|ARBA:ARBA00031126};
GN Name=106054041 {ECO:0000313|EnsemblMetazoa:BGLB037177-PA};
OS Biomphalaria glabrata (Bloodfluke planorb) (Freshwater snail).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Heterobranchia; Euthyneura; Panpulmonata; Hygrophila; Lymnaeoidea;
OC Planorbidae; Biomphalaria.
OX NCBI_TaxID=6526 {ECO:0000313|EnsemblMetazoa:BGLB037177-PA, ECO:0000313|Proteomes:UP000076420};
RN [1] {ECO:0000313|EnsemblMetazoa:BGLB037177-PA}
RP IDENTIFICATION.
RC STRAIN=BB02 {ECO:0000313|EnsemblMetazoa:BGLB037177-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- FUNCTION: Component of the sequence-specific heterotrimeric
CC transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3'
CC box motif found in the promoters of its target genes. NF-Y can function
CC as both an activator and a repressor, depending on its interacting
CC cofactors. {ECO:0000256|ARBA:ARBA00025263}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the NFYB/HAP3 subunit family.
CC {ECO:0000256|ARBA:ARBA00009053}.
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DR RefSeq; XP_013065202.1; XM_013209748.1.
DR RefSeq; XP_013065203.1; XM_013209749.1.
DR AlphaFoldDB; A0A2C9M0P9; -.
DR STRING; 6526.A0A2C9M0P9; -.
DR EnsemblMetazoa; BGLB037177-RA; BGLB037177-PA; BGLB037177.
DR EnsemblMetazoa; BGLB037177-RB; BGLB037177-PB; BGLB037177.
DR KEGG; bgt:106054041; -.
DR VEuPathDB; VectorBase:BGLB037177; -.
DR OrthoDB; 24067at2759; -.
DR Proteomes; UP000076420; Unassembled WGS sequence.
DR GO; GO:0016602; C:CCAAT-binding factor complex; IEA:InterPro.
DR GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:InterPro.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR InterPro; IPR003958; CBFA_NFYB_domain.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR027113; Transc_fact_NFYB/HAP3.
DR InterPro; IPR003956; Transcrpt_fac_NFYB/HAP3_CS.
DR PANTHER; PTHR11064; CCAAT-BINDING TRANSCRIPTION FACTOR-RELATED; 1.
DR PANTHER; PTHR11064:SF9; NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT BETA; 1.
DR Pfam; PF00808; CBFD_NFYB_HMF; 1.
DR PRINTS; PR00615; CCAATSUBUNTA.
DR SUPFAM; SSF47113; Histone-fold; 1.
DR PROSITE; PS00685; NFYB_HAP3; 1.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 88..152
FT /note="Transcription factor CBF/NF-Y/archaeal histone"
FT /evidence="ECO:0000259|Pfam:PF00808"
FT REGION 58..80
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 249 AA; 28132 MW; BD5B851D57A9ED11 CRC64;
MTFFAEWLEL LQFHWLLIDQ PISPNLLNQR DINKMNDSHD GSEDAHLGPL IQQGGYDVDA
ENGGLGSPEM EEDTKHSMDE PLREQDRFLP IANVARIMKK AVPSTGKIAK DAKECVQECV
SEFISFITSE ASERCHQEKR KTINGEDILF AMSTLGFDNY VEPLKLYLQK YRECSKGEKN
VSSLPGPDTS DELSDDMLVA QSLNNSLMSD QNGQQNVIYT TTYAPGHVKL LPDNLQIQCH
WPIVLKQDE
//
