ID A0A2C9M3N2_BIOGL Unreviewed; 594 AA.
AC A0A2C9M3N2;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Rab11 family-interacting protein 4B-like isoform X1 {ECO:0000313|RefSeq:XP_013066241.1};
GN Name=106054770 {ECO:0000313|EnsemblMetazoa:BGLB038158-PD};
GN Synonyms=LOC106054770 {ECO:0000313|RefSeq:XP_013066241.1};
OS Biomphalaria glabrata (Bloodfluke planorb) (Freshwater snail).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Heterobranchia; Euthyneura; Panpulmonata; Hygrophila; Lymnaeoidea;
OC Planorbidae; Biomphalaria.
OX NCBI_TaxID=6526 {ECO:0000313|EnsemblMetazoa:BGLB038158-PD, ECO:0000313|Proteomes:UP000076420};
RN [1] {ECO:0000313|EnsemblMetazoa:BGLB038158-PD}
RP IDENTIFICATION.
RC STRAIN=BB02 {ECO:0000313|EnsemblMetazoa:BGLB038158-PD};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_013066241.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cleavage furrow {ECO:0000256|ARBA:ARBA00004626}.
CC Endosome membrane {ECO:0000256|ARBA:ARBA00004481}; Peripheral membrane
CC protein {ECO:0000256|ARBA:ARBA00004481}. Membrane
CC {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004170}. Midbody
CC {ECO:0000256|ARBA:ARBA00004214}. Recycling endosome membrane
CC {ECO:0000256|ARBA:ARBA00004654}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004654}.
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DR RefSeq; XP_013066241.1; XM_013210787.2.
DR AlphaFoldDB; A0A2C9M3N2; -.
DR STRING; 6526.A0A2C9M3N2; -.
DR EnsemblMetazoa; BGLB038158-RD; BGLB038158-PD; BGLB038158.
DR GeneID; 106054770; -.
DR KEGG; bgt:106054770; -.
DR VEuPathDB; VectorBase:BGLB038158; -.
DR OrthoDB; 5312348at2759; -.
DR Proteomes; UP000076420; Unassembled WGS sequence.
DR Proteomes; UP001165740; Chromosome 2.
DR GO; GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.
DR GO; GO:0030496; C:midbody; IEA:UniProtKB-SubCell.
DR GO; GO:0055038; C:recycling endosome membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR Gene3D; 1.10.287.1490; -; 1.
DR Gene3D; 1.20.5.2440; -; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR037245; FIP-RBD_C_sf.
DR InterPro; IPR019018; Rab-bd_FIP-RBD.
DR PANTHER; PTHR15726:SF7; NUCLEAR FALLOUT, ISOFORM J; 1.
DR PANTHER; PTHR15726; RAB11-FAMILY INTERACTING PROTEIN; 1.
DR Pfam; PF13499; EF-hand_7; 1.
DR Pfam; PF09457; RBD-FIP; 1.
DR SMART; SM00054; EFh; 2.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF144270; Eferin C-derminal domain-like; 1.
DR PROSITE; PS50222; EF_HAND_2; 2.
DR PROSITE; PS51511; FIP_RBD; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP001165740}.
FT DOMAIN 6..41
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 45..80
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 530..592
FT /note="FIP-RBD"
FT /evidence="ECO:0000259|PROSITE:PS51511"
FT REGION 168..277
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 369..410
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 225..239
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 247..274
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 594 AA; 69004 MW; 9416C79C5193ED47 CRC64;
MEEHSEFSDK FKQIFDLCDV DKDGYIDVHH FQELAKDHFF GAECTETEQL TGIINLLDPE
GRGLISYSDF CDGVQQIIEL QQQVSRNFKN SVSQETLVSE DTLVPLDIAG DLSVFESQKT
SPSSSHNTYA EYDFSSFDDF GLVDLSANGS SSNTSNIVLP QTELNGNPFL LPNLSEDDGD
SAISGKSSEI NESSRQEITD EENYEDYGEI ESEADVSDQG HLTPSTQRKR ADRKDPLTRH
KRSCPNRRIT SASLASQLQR SGKNSPSSTR RSSFGSDEIF DDIEGNFQNV DGRLKFLEDQ
LQHLTEVQTE TNTKQIKLKD ENNTLVQKVL YLEEQLRDME VKSEDRLHDE RRKYQDYISK
QEREKNEQVD YITQRLHRIE HEYEELKQEA PRLQSEISKL RTEKMDIQER LLERQETYNI
LYDEHEKLKA DYHRQEVLNQ KERNATGQLL SEMEKELDEL RRYRMEVETG ARSPTGSISE
LPGRYRDLQN EIHKLREAMW FEWKDLCQEN KHLHDSNEEL NAQLLNQCIG EGKSLLHNTQ
GQSLAQELEH LTKEELLAQL KLERDVNFRL KQYVDHIIMT ILEKNPSLLD ITHR
//
