ID   A0A2C9M895_BIOGL        Unreviewed;       228 AA.
AC   A0A2C9M895;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   13-SEP-2023, entry version 24.
DE   RecName: Full=MARVEL domain-containing protein {ECO:0000259|PROSITE:PS51225};
GN   Name=106074534 {ECO:0000313|EnsemblMetazoa:BGLB039592-PC};
OS   Biomphalaria glabrata (Bloodfluke planorb) (Freshwater snail).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Heterobranchia; Euthyneura; Panpulmonata; Hygrophila; Lymnaeoidea;
OC   Planorbidae; Biomphalaria.
OX   NCBI_TaxID=6526 {ECO:0000313|EnsemblMetazoa:BGLB039592-PC, ECO:0000313|Proteomes:UP000076420};
RN   [1] {ECO:0000313|EnsemblMetazoa:BGLB039592-PC}
RP   IDENTIFICATION.
RC   STRAIN=BB02 {ECO:0000313|EnsemblMetazoa:BGLB039592-PC};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the synaptophysin/synaptobrevin family.
CC       {ECO:0000256|ARBA:ARBA00006476}.
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DR   RefSeq; XP_013090761.1; XM_013235307.1.
DR   AlphaFoldDB; A0A2C9M895; -.
DR   STRING; 6526.A0A2C9M895; -.
DR   EnsemblMetazoa; BGLB039592-RC; BGLB039592-PC; BGLB039592.
DR   KEGG; bgt:106074534; -.
DR   VEuPathDB; VectorBase:BGLB039592; -.
DR   OrthoDB; 2881347at2759; -.
DR   Proteomes; UP000076420; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008021; C:synaptic vesicle; IEA:InterPro.
DR   InterPro; IPR008253; Marvel.
DR   InterPro; IPR001285; Synaptophysin/porin.
DR   PANTHER; PTHR10306:SF17; MARVEL DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR10306; SYNAPTOPHYSIN; 1.
DR   Pfam; PF01284; MARVEL; 1.
DR   PRINTS; PR00220; SYNAPTOPHYSN.
DR   PROSITE; PS51225; MARVEL; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|PROSITE-ProRule:PRU00581, ECO:0000256|SAM:Phobius};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|PROSITE-ProRule:PRU00581,
KW   ECO:0000256|SAM:Phobius}; Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..16
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           17..228
FT                   /note="MARVEL domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5012813063"
FT   TRANSMEM        82..104
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        116..138
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        178..198
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          1..202
FT                   /note="MARVEL"
FT                   /evidence="ECO:0000259|PROSITE:PS51225"
FT   REGION          209..228
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        210..228
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   228 AA;  25625 MW;  48F0D893331A2BFE CRC64;
     MIIFIILLKI LDVVLSIFAF ATTTSHKSST TFSILCANAT QPEDRTFYYS YPYDLESECF
     KLCDTDAKQF CLLSGSKSSA EFYVFVGVIV FLYCLAALVL YIFFDDLYRR NTRLVIVDFI
     ISVVLTLLWI IASSAWAAGV SDVKTYTDPE EGGIFGTDQC QKDLCKVKSL GNFASLNVSL
     IFGFLNFGVW IGNLWFIYKE TPWFKLTSKP PTEPASTPQS VDSSINHI
//