ID   A0A2C9M9F0_BIOGL        Unreviewed;      1546 AA.
AC   A0A2C9M9F0;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=Fibronectin type-III domain-containing protein {ECO:0000259|PROSITE:PS50853};
GN   Name=106075017 {ECO:0000313|EnsemblMetazoa:BGLB040090-PC};
OS   Biomphalaria glabrata (Bloodfluke planorb) (Freshwater snail).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Heterobranchia; Euthyneura; Panpulmonata; Hygrophila; Lymnaeoidea;
OC   Planorbidae; Biomphalaria.
OX   NCBI_TaxID=6526 {ECO:0000313|EnsemblMetazoa:BGLB040090-PC, ECO:0000313|Proteomes:UP000076420};
RN   [1] {ECO:0000313|EnsemblMetazoa:BGLB040090-PC}
RP   IDENTIFICATION.
RC   STRAIN=BB02 {ECO:0000313|EnsemblMetazoa:BGLB040090-PC};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   RefSeq; XP_013091387.1; XM_013235933.1.
DR   STRING; 6526.A0A2C9M9F0; -.
DR   EnsemblMetazoa; BGLB040090-RC; BGLB040090-PC; BGLB040090.
DR   GeneID; 106075017; -.
DR   KEGG; bgt:106075017; -.
DR   VEuPathDB; VectorBase:BGLB040090; -.
DR   OrthoDB; 5477547at2759; -.
DR   Proteomes; UP000076420; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   CDD; cd00063; FN3; 2.
DR   Gene3D; 6.10.250.2590; -; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR   Gene3D; 2.120.10.80; Kelch-type beta propeller; 2.
DR   InterPro; IPR003961; FN3_dom.
DR   InterPro; IPR036116; FN3_sf.
DR   InterPro; IPR043536; HCF1/2.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR015915; Kelch-typ_b-propeller.
DR   InterPro; IPR006652; Kelch_1.
DR   PANTHER; PTHR46003; HOST CELL FACTOR; 1.
DR   PANTHER; PTHR46003:SF1; HOST CELL FACTOR; 1.
DR   Pfam; PF01344; Kelch_1; 1.
DR   Pfam; PF13415; Kelch_3; 1.
DR   Pfam; PF13854; Kelch_5; 1.
DR   SMART; SM00060; FN3; 3.
DR   SUPFAM; SSF49265; Fibronectin type III; 1.
DR   SUPFAM; SSF117281; Kelch motif; 1.
DR   PROSITE; PS50853; FN3; 1.
PE   4: Predicted;
KW   Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          1307..1398
FT                   /note="Fibronectin type-III"
FT                   /evidence="ECO:0000259|PROSITE:PS50853"
FT   REGION          1043..1104
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1184..1214
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1510..1546
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1080..1095
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1184..1198
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1199..1214
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1546 AA;  161907 MW;  A77FEF3915F514CD CRC64;
     MAAPILKWKR VTNTSGPAPR PRHGHRAVAI KDLMIVFGGG NEGIVDELHV YNTSTNQWFV
     PAVRGDIPPG CAAYGFICDG TRILVFGGMV EYGKYSNELY ELQASRWEWK RLKPRAPKSG
     QPPCPRLGHS FTLLGNKGYL FGGLANDSED PKNNIPRYLN DLYTLELRPL ANHNLSWDLP
     NIVGVPPPPR ESHSAAPYTD KDGRKPRLFI YGGMSGCRLG DLWMLDVDSV SWVQPTVSGM
     PPLPRSLHSA TVIGSRMFIF GGWVPLVMED VKVATHEKEW KCTNTLASLN LESMTWEPLA
     MEVFEDALPR ARAGHCAVAI NTRLYIWSGR DGYRKAWNNQ VCFKDLWFLE TEKPPAPTRV
     QLVRASTNTL EVSWGAVPTA DAYLLQLQKY DLPPSTTTAA TTAACNPTVA TTATPTIPTP
     ATAVATAASI TPTPAMTQTR PQFQITGQGG AIIRTPTTGL PLRTVTSVVS PLTPGHTTQT
     IRVTAAPRIR APVTITPVAN TIRLGTPQMA QALQRVVTPT TTGTMSGIAA LAAAAAATQK
     IAGTMASATT TPASGIKVVT PTIVTPGGVK VTPVTGKLPT NTIAPGTQTV RVAPTGATIL
     KASGSGTNLA GKQIITVHKQ GSTGTSQSQI VTLVKTTQGM AMATPKNPLP QGATIVKLVT
     TQAGGINKPT TVLSTQSGGQ TPTILGISSV QPTQPSTPGQ KTLTTMIRTI PTSMLSMAKT
     GQGATQGGTT TPVGTKTIVI AAPKGTAGSL NQPTKIITSV PKLAGQTGNT QFIVVSPQSM
     AGAVAAGNKP ATAITSFTSG GNIITQSGKP VITVLSGGST TGTHSVTPAG GHTVVSSPTM
     RVVSSNASTI SLITQAANEA SASGGRQIVT VPAGHAGLAG SKGPVQITIT PANRGGINTI
     TLPTNLRQMA KPVVVSAPAA NGTQVVSLGG AGNAQVLTVT PTPSASGAAD QVATLVSTEA
     APADSVGDAG QAAEGEGAIQ QFDGTSDDII EDGEVCHFES TLMLYSSSLT DAMEEDVEYF
     EESYCKPDHD HLYSLPNYCE DEDYTIPQFD GAGDGGSDDE GGQEEAPDKE MPVEEDHDTP
     METAEQEEGQ ESSELEGTES EGVTNQQAME EGLHADMGHI EPSLLAQDEG SNNHMTDAEL
     QQQAESALEA LAEAGGVLSA HGMLEDHGLM DSVGLDGMLA QPTSALDTSQ NSVEHEDSAG
     ELTQPEDENE TKPDIDLNHA ETANSSDAMD VAENGNLVPK EEPSDETIAQ LAQTLAGASN
     NAGDASDPLA TLASAAISSA PVATPKMSDA SVGSIDSKID DMKPEMKQER ILVKKDQQQW
     FDVGFIKTTS CTVSHYHLPS ENAQGNADDI DVVNVPDHSV LKRQELQPGT AYKFRVAGIN
     ACGRGPFSEV SAFKTCLPGF PGAPSAIKIS KSGDGAHLSW EPPQNTAGKI IEYSVYLAVR
     NQSQDTKPGA PAQLAFVRVF CGPLPSCVVT NSSLTSAHID YTTKPAIIFR IAARNEKGYG
     PATQVRWLQD ASQSPAAGRG AKRQGTENVK PGSVVKKLKV EDGGEG
//