ID   A0A2C9M9S4_BIOGL        Unreviewed;       588 AA.
AC   A0A2C9M9S4;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=Acyl-coenzyme A oxidase {ECO:0000256|PIRNR:PIRNR000168};
GN   Name=106054747 {ECO:0000313|EnsemblMetazoa:BGLB040182-PA};
OS   Biomphalaria glabrata (Bloodfluke planorb) (Freshwater snail).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Heterobranchia; Euthyneura; Panpulmonata; Hygrophila; Lymnaeoidea;
OC   Planorbidae; Biomphalaria.
OX   NCBI_TaxID=6526 {ECO:0000313|EnsemblMetazoa:BGLB040182-PA, ECO:0000313|Proteomes:UP000076420};
RN   [1] {ECO:0000313|EnsemblMetazoa:BGLB040182-PA}
RP   IDENTIFICATION.
RC   STRAIN=BB02 {ECO:0000313|EnsemblMetazoa:BGLB040182-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- PATHWAY: Lipid metabolism; peroxisomal fatty acid beta-oxidation.
CC       {ECO:0000256|ARBA:ARBA00004846}.
CC   -!- SIMILARITY: Belongs to the acyl-CoA oxidase family.
CC       {ECO:0000256|ARBA:ARBA00006288, ECO:0000256|PIRNR:PIRNR000168}.
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DR   RefSeq; XP_013066209.1; XM_013210755.1.
DR   RefSeq; XP_013066210.1; XM_013210756.1.
DR   AlphaFoldDB; A0A2C9M9S4; -.
DR   EnsemblMetazoa; BGLB040182-RA; BGLB040182-PA; BGLB040182.
DR   EnsemblMetazoa; BGLB040182-RC; BGLB040182-PC; BGLB040182.
DR   VEuPathDB; VectorBase:BGLB040182; -.
DR   OrthoDB; 5777at2759; -.
DR   Proteomes; UP000076420; Unassembled WGS sequence.
DR   GO; GO:0005777; C:peroxisome; IEA:InterPro.
DR   GO; GO:0003997; F:acyl-CoA oxidase activity; IEA:InterPro.
DR   GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; IEA:InterPro.
DR   Gene3D; 2.40.110.10; Butyryl-CoA Dehydrogenase, subunit A, domain 2; 1.
DR   Gene3D; 1.20.140.10; Butyryl-CoA Dehydrogenase, subunit A, domain 3; 2.
DR   InterPro; IPR006091; Acyl-CoA_Oxase/DH_mid-dom.
DR   InterPro; IPR046373; Acyl-CoA_Oxase/DH_mid-dom_sf.
DR   InterPro; IPR012258; Acyl-CoA_oxidase.
DR   InterPro; IPR002655; Acyl-CoA_oxidase_C.
DR   InterPro; IPR036250; AcylCo_DH-like_C.
DR   InterPro; IPR009100; AcylCoA_DH/oxidase_NM_dom_sf.
DR   PANTHER; PTHR10909; ELECTRON TRANSPORT OXIDOREDUCTASE; 1.
DR   PANTHER; PTHR10909:SF352; PEROXISOMAL ACYL-COENZYME A OXIDASE 3; 1.
DR   Pfam; PF01756; ACOX; 1.
DR   Pfam; PF02770; Acyl-CoA_dh_M; 1.
DR   PIRSF; PIRSF000168; Acyl-CoA_oxidase; 1.
DR   SUPFAM; SSF47203; Acyl-CoA dehydrogenase C-terminal domain-like; 2.
DR   SUPFAM; SSF56645; Acyl-CoA dehydrogenase NM domain-like; 1.
PE   3: Inferred from homology;
KW   FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|PIRNR:PIRNR000168};
KW   Flavoprotein {ECO:0000256|ARBA:ARBA00022630,
KW   ECO:0000256|PIRNR:PIRNR000168}.
FT   DOMAIN          44..153
FT                   /note="Acyl-CoA oxidase/dehydrogenase middle"
FT                   /evidence="ECO:0000259|Pfam:PF02770"
FT   DOMAIN          399..579
FT                   /note="Acyl-CoA oxidase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF01756"
FT   ACT_SITE        339
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000168-1"
FT   BINDING         48
FT                   /ligand="FAD"
FT                   /ligand_id="ChEBI:CHEBI:57692"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000168-2"
FT   BINDING         87
FT                   /ligand="FAD"
FT                   /ligand_id="ChEBI:CHEBI:57692"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000168-2"
SQ   SEQUENCE   588 AA;  65281 MW;  5D135D52631A2CCE CRC64;
     MYDWTVSAKW NLNVEMFSGT VRNMGSQRHN DIVEQSKANQ NFGCFILTEL SHGSNTKNMR
     TTATYDSKTQ EFVINTPDFE ATKIWVGNLG KQATHGILYA QLYTEDGLCH GLHTFVAQIR
     DPKTLLALPG VLVGDMGEKI GLNGLDNGFV AFNQFRIPRE NLLDKFGDVT PSGEYVTPYK
     DPSKRFGASL GALSGGRVGI TGMGVANLRL CMPIAIRYSA VRRQFGPGSD EIAVIEYQLQ
     QWRLFPYLAA TYALDIFSTS FFMNFVELRI GVMVGDKSQR QADLGKEIHA LSCASKPLSG
     WVARDAIQEC REACGGHGYF KVNRLGDIRN DHDPNNTYEG DNNVLLQQTS NYLLSFVEPA
     SAGESISSPL GSVNFLTNLQ QRLKSKFTAK TIEDCLNPLV ALDAYKWLVS YLLVESNRRL
     AEQTSSGKDP FTARNDSQAY YCRSLALAFI EHTVLERFVL ILESKNDEPT PVALRPVLQR
     LCTLYGLWSL EKHLATLYQG GYVSGGDSPR LIRETILQLC TLLKPDAVSL VDAIAPPDFI
     LNSPIGCSDG QIYKNLYSAM LQGSKSLERA EYWQEAITPP PPRTPAKL
//