ID A0A2C9MA70_BIOGL Unreviewed; 827 AA.
AC A0A2C9MA70;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Tripartite motif-containing protein 2-like {ECO:0008006|Google:ProtNLM};
GN Name=106075931 {ECO:0000313|EnsemblMetazoa:BGLB040308-PB};
OS Biomphalaria glabrata (Bloodfluke planorb) (Freshwater snail).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Heterobranchia; Euthyneura; Panpulmonata; Hygrophila; Lymnaeoidea;
OC Planorbidae; Biomphalaria.
OX NCBI_TaxID=6526 {ECO:0000313|EnsemblMetazoa:BGLB040308-PB, ECO:0000313|Proteomes:UP000076420};
RN [1] {ECO:0000313|EnsemblMetazoa:BGLB040308-PB}
RP IDENTIFICATION.
RC STRAIN=BB02 {ECO:0000313|EnsemblMetazoa:BGLB040308-PB};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the TRIM/RBCC family.
CC {ECO:0000256|ARBA:ARBA00008518}.
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DR RefSeq; XP_013092265.1; XM_013236811.1.
DR AlphaFoldDB; A0A2C9MA70; -.
DR EnsemblMetazoa; BGLB040308-RB; BGLB040308-PB; BGLB040308.
DR GeneID; 106075931; -.
DR VEuPathDB; VectorBase:BGLB040308; -.
DR OrthoDB; 2901369at2759; -.
DR Proteomes; UP000076420; Unassembled WGS sequence.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd14960; NHL_TRIM2_like; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.120.10.30; TolB, C-terminal domain; 2.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR003649; Bbox_C.
DR InterPro; IPR017868; Filamin/ABP280_repeat-like.
DR InterPro; IPR001298; Filamin/ABP280_rpt.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR001258; NHL_repeat.
DR InterPro; IPR047153; TRIM45/56/19.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR018957; Znf_C3HC4_RING-type.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR25462; BONUS, ISOFORM C-RELATED; 1.
DR PANTHER; PTHR25462:SF229; NHL (RING FINGER B-BOX COILED COIL) DOMAIN CONTAINING; 1.
DR Pfam; PF00630; Filamin; 1.
DR Pfam; PF01436; NHL; 6.
DR Pfam; PF00643; zf-B_box; 1.
DR Pfam; PF00097; zf-C3HC4; 1.
DR SMART; SM00502; BBC; 1.
DR SMART; SM00336; BBOX; 2.
DR SMART; SM00557; IG_FLMN; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF101898; NHL repeat; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50194; FILAMIN_REPEAT; 1.
DR PROSITE; PS51125; NHL; 6.
DR PROSITE; PS50119; ZF_BBOX; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00024}.
FT DOMAIN 33..74
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 198..239
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT REPEAT 406..508
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 559..599
FT /note="NHL"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00504"
FT REPEAT 605..646
FT /note="NHL"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00504"
FT REPEAT 647..688
FT /note="NHL"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00504"
FT REPEAT 692..735
FT /note="NHL"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00504"
FT REPEAT 739..782
FT /note="NHL"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00504"
FT REPEAT 783..826
FT /note="NHL"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00504"
FT REGION 517..550
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 532..546
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 827 AA; 90035 MW; 5B191157F5E6F42F CRC64;
MNNIAGAVSR MTAIRMTSTA ARFWGSNINL LSCAICDHRY KDPKVLPCLH SFCEQCLSNV
IPSESLSVTC PVCRQQSILP LDGVAALQNN NFLLNLLKVI TSPEVCTSCG QLASIPTSKC
LDCQEILCAN CSIKHTNMDN TNNNVGGSDH HRDTTNKMED APQEKKEVPG QHHLVLLAEA
PTCKSNSLTN GGSKEVELGA IVCPSHAGSP LKYYCSLCDT AVCETCTQVE HIGHMTVILS
EAVTEHKTSL ASLVSRVRQM TPEVQHAIEE VDAVQEVLCR NKLAAEHRIT DLFNEMTSLL
EARKKSAIEE LSRVSAIKER VLEEQKRSLK KHLTCISSCC DLTEDSLLHG NDTDVVMVKK
EMAGKLNDLL ACGISLQPET NPLIVFDDKD FEGLRETITG IGCVCNNAAV PHQTTVGGEA
FSNCIVGKAS TVTVTTRDRN GDLVKTGFAP ITASLSTDKS EERLFPTITD HQNGTYDLTF
VLQSPGVYYL SVCMFGLHTK GSPYKIRAVD IGDANGNGTT RIPRTMAVKQ KGVKRPSSSR
SQGSSNRRTN RIEDDLIIRI GVKGRNKGEF SNPQGLCYHD ERVLVADSNN QTVQIFLPSG
ECCLKFGTPG RAPGKMQRPT GVAVTLNGNY LVADYDNKWV SVFNPEGKYV SRIGIGRLQG
PKGIVVDKEG RIIVVDNKSS CVLIFQSNGK LLHKFGSRGN RDDQFAGPHY AAVNENNDII
ISDFHNHCVK VFDRDGNFKF CFGSCGEGNG QFNAPTGVAV DDKGNMLVAD WGNSRIQVFD
STGSFLSYVN TASEPLYGPQ GLAVASLGVL VVADSGNHCF KYYKYLQ
//
