ID A0A2C9U3E5_MANES Unreviewed; 1019 AA.
AC A0A2C9U3E5;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Sucrose-phosphate synthase {ECO:0000256|ARBA:ARBA00012536, ECO:0000256|RuleBase:RU368006};
DE EC=2.4.1.14 {ECO:0000256|ARBA:ARBA00012536, ECO:0000256|RuleBase:RU368006};
GN Name=SPS4 {ECO:0000313|EMBL:QAY30717.1};
GN ORFNames=MANES_18G109400 {ECO:0000313|EMBL:OAY23815.1};
OS Manihot esculenta (Cassava) (Jatropha manihot).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Manihoteae;
OC Manihot.
OX NCBI_TaxID=3983 {ECO:0000313|EMBL:OAY23815.1, ECO:0000313|Proteomes:UP000091857};
RN [1] {ECO:0000313|EMBL:OAY23815.1, ECO:0000313|Proteomes:UP000091857}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AM560-2 {ECO:0000313|Proteomes:UP000091857};
RC TISSUE=Leaf {ECO:0000313|EMBL:OAY23815.1};
RA Bredeson J.V., Prochnik S.E., Lyons J.B., Schmutz J., Grimwood J.,
RA Vrebalov J., Bart R.S., Amuge T., Ferguson M.E., Green R., Putnam N.,
RA Stites J., Rounsley S., Rokhsar D.S.;
RT "WGS assembly of Manihot esculenta.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:QAY30717.1}
RP NUCLEOTIDE SEQUENCE.
RA Huang T., Luo X., Wei M., Shan Z.;
RT "Cloning and Expression Analysis of Sucrose Phosphate Synthase Gene Family
RT in Cassava(Manihot esculenta).";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Plays a role in photosynthetic sucrose synthesis by
CC catalyzing the rate-limiting step of sucrose biosynthesis from UDP-
CC glucose and fructose- 6-phosphate. Involved in the regulation of carbon
CC partitioning in the leaves of plants. May regulate the synthesis of
CC sucrose and therefore play a major role as a limiting factor in the
CC export of photoassimilates out of the leaf. Plays a role for sucrose
CC availability that is essential for plant growth and fiber elongation.
CC {ECO:0000256|RuleBase:RU368006}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=beta-D-fructose 6-phosphate + UDP-alpha-D-glucose = H(+) +
CC sucrose 6(F)-phosphate + UDP; Xref=Rhea:RHEA:22172,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:57634, ChEBI:CHEBI:57723,
CC ChEBI:CHEBI:58223, ChEBI:CHEBI:58885; EC=2.4.1.14;
CC Evidence={ECO:0000256|ARBA:ARBA00001481,
CC ECO:0000256|RuleBase:RU368006};
CC -!- PATHWAY: Glycan biosynthesis; sucrose biosynthesis; sucrose from D-
CC fructose 6-phosphate and UDP-alpha-D-glucose: step 1/2.
CC {ECO:0000256|ARBA:ARBA00005027, ECO:0000256|RuleBase:RU368006}.
CC -!- SUBUNIT: Homodimer or homotetramer. {ECO:0000256|ARBA:ARBA00011774,
CC ECO:0000256|RuleBase:RU368006}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC {ECO:0000256|ARBA:ARBA00006530, ECO:0000256|RuleBase:RU368006}.
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DR EMBL; CM004404; OAY23815.1; -; Genomic_DNA.
DR EMBL; MK181570; QAY30717.1; -; mRNA.
DR AlphaFoldDB; A0A2C9U3E5; -.
DR STRING; 3983.A0A2C9U3E5; -.
DR EnsemblPlants; OAY23815; OAY23815; MANES_18G109400.
DR Gramene; OAY23815; OAY23815; MANES_18G109400.
DR OMA; YEAHVEY; -.
DR OrthoDB; 1206157at2759; -.
DR UniPathway; UPA00371; UER00545.
DR Proteomes; UP000091857; Chromosome lg18.
DR GO; GO:0016157; F:sucrose synthase activity; IEA:InterPro.
DR GO; GO:0046524; F:sucrose-phosphate synthase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0005986; P:sucrose biosynthetic process; IEA:UniProtKB-UniRule.
DR CDD; cd03800; GT4_sucrose_synthase; 1.
DR CDD; cd16419; HAD_SPS; 1.
DR Gene3D; 3.90.1070.10; -; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR001296; Glyco_trans_1.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR006380; SPP-like_dom.
DR InterPro; IPR035659; SPS_C.
DR InterPro; IPR012819; SPS_pln.
DR InterPro; IPR000368; Sucrose_synth.
DR NCBIfam; TIGR02468; sucrsPsyn_pln; 1.
DR PANTHER; PTHR46039; SUCROSE-PHOSPHATE SYNTHASE 3-RELATED; 1.
DR PANTHER; PTHR46039:SF1; SUCROSE-PHOSPHATE SYNTHASE 4; 1.
DR Pfam; PF00534; Glycos_transf_1; 1.
DR Pfam; PF05116; S6PP; 1.
DR Pfam; PF00862; Sucrose_synth; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE 2: Evidence at transcript level;
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676,
KW ECO:0000256|RuleBase:RU368006};
KW Reference proteome {ECO:0000313|Proteomes:UP000091857};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU368006}.
FT DOMAIN 251..396
FT /note="Sucrose synthase"
FT /evidence="ECO:0000259|Pfam:PF00862"
FT DOMAIN 471..644
FT /note="Glycosyl transferase family 1"
FT /evidence="ECO:0000259|Pfam:PF00534"
FT DOMAIN 783..953
FT /note="Sucrose phosphatase-like"
FT /evidence="ECO:0000259|Pfam:PF05116"
FT REGION 117..146
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 117..142
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1019 AA; 115297 MW; 55474617045218C5 CRC64;
MAGNDWINGY LEAILDVGSS LRKRNDGQLK ISKFEDSKQK EDKSFSPTKY FVEEVINSFD
ESDLHRTWVK VIATRNTRER SNRLENMCWR IWHLARMKKK IEWDDAQRLA RRRLEREQGR
NDAADDLSEL SEGEKEKGDT NLSEPVKNFS RINSDMQIWS DEEKPRRLYI VLISMHGLVR
GENMELGRDS DTGGQVKYVV ELARALANTK GVYRVDLLTR QISSPEVDYS YGEPIEMLAC
PPDGSGSCGA YIVRIPCGPR EKYIPKESLW PYIPEFVDGA LSHIVNMARA LGEQVNGGKP
TWPYVIHGHY ADAGEVASHL SGALNVPMVL TGHSLGRNKF EQLLKQGRLS KEDINVTYKI
MRRIEAEELG LDATEMVVTS TKQEIEEQWG LYDGFDIKLE RKLRVRRRRG VSCMGRHMPR
MVVIPPGMDF SYVTTHDSLE GDLKSLIGPD RTQTKRNLPP IWSEVMRFFT NPHKPTILAL
SRPDPKKNVT TLLKAFGECQ RLRELANLTL ILGNRDDIEE MSNSSSVVLT TVLKLIDKYD
LYGQVAYPKH HKQSEVPDIY RLAAKTKGVF INPALVEPFG LTLIEAAAYG LPVVATKNGG
PVDILKALNN GLLVDPHDQK AIADALLKLV ADKNLWTECR KNGLKNIHRF SWPEHCRNYL
SHIEHCRNRH PTSRLEITPV PEEPMSDSLK DVEDLSLRFS IEGDPKLNGE LDATTRQKKL
IEAITQAASF NGNTNVTYSP GRRQMLFVIA VDCYDCNGKS TETFQEIIKN VMKAAGSCLG
LGRIGFVLST GSSLQETMEA LRYCPVNIED FDAIICNSGS EMYCPWRDMV ADLDYEAHVG
YRWPGENVRS MAIRLAKVED GAEDDVLEYV QASGSRSYSY IIKPGAKTRK VDEIRQRLRM
RGIRCSLVYT RAASRLNVIP LFASRKQALR YLSVRWGIDL SKIVVFVGEK GDTDYEELLA
GLHKTLIMRG SVEYGSENLL CGQDGFKRED IIPQESPSLR FVEENYENLS TALETLGIK
//
