ID A0A2C9U5Y1_MANES Unreviewed; 561 AA.
AC A0A2C9U5Y1;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=ENTH domain-containing protein {ECO:0000259|PROSITE:PS50942};
GN ORFNames=MANES_17G080600 {ECO:0000313|EMBL:OAY25269.1};
OS Manihot esculenta (Cassava) (Jatropha manihot).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Manihoteae;
OC Manihot.
OX NCBI_TaxID=3983 {ECO:0000313|EMBL:OAY25269.1, ECO:0000313|Proteomes:UP000091857};
RN [1] {ECO:0000313|EMBL:OAY25269.1, ECO:0000313|Proteomes:UP000091857}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AM560-2 {ECO:0000313|Proteomes:UP000091857};
RC TISSUE=Leaf {ECO:0000313|EMBL:OAY25269.1};
RA Bredeson J.V., Prochnik S.E., Lyons J.B., Schmutz J., Grimwood J.,
RA Vrebalov J., Bart R.S., Amuge T., Ferguson M.E., Green R., Putnam N.,
RA Stites J., Rounsley S., Rokhsar D.S.;
RT "WGS assembly of Manihot esculenta.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, clathrin-coated vesicle
CC {ECO:0000256|ARBA:ARBA00004132}. Golgi apparatus
CC {ECO:0000256|ARBA:ARBA00004555}. Membrane, clathrin-coated pit
CC {ECO:0000256|ARBA:ARBA00004600}. Vesicle
CC {ECO:0000256|ARBA:ARBA00004373}.
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DR EMBL; CM004403; OAY25269.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2C9U5Y1; -.
DR STRING; 3983.A0A2C9U5Y1; -.
DR EnsemblPlants; OAY25269; OAY25269; MANES_17G080600.
DR Gramene; OAY25269; OAY25269; MANES_17G080600.
DR OMA; MVPIKEP; -.
DR OrthoDB; 3667239at2759; -.
DR Proteomes; UP000091857; Chromosome lg17.
DR GO; GO:0005905; C:clathrin-coated pit; IBA:GO_Central.
DR GO; GO:0030136; C:clathrin-coated vesicle; IBA:GO_Central.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR GO; GO:0005545; F:1-phosphatidylinositol binding; IBA:GO_Central.
DR GO; GO:0032050; F:clathrin heavy chain binding; IBA:GO_Central.
DR GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IBA:GO_Central.
DR GO; GO:0000149; F:SNARE binding; IBA:GO_Central.
DR GO; GO:0048268; P:clathrin coat assembly; IEA:InterPro.
DR GO; GO:0072583; P:clathrin-dependent endocytosis; IBA:GO_Central.
DR GO; GO:0006900; P:vesicle budding from membrane; IBA:GO_Central.
DR CDD; cd03564; ANTH_N; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR Gene3D; 1.20.58.150; ANTH domain; 1.
DR InterPro; IPR011417; ANTH_dom.
DR InterPro; IPR014712; ANTH_dom_sf.
DR InterPro; IPR048050; ANTH_N_plant.
DR InterPro; IPR045192; AP180-like.
DR InterPro; IPR013809; ENTH.
DR InterPro; IPR008942; ENTH_VHS.
DR PANTHER; PTHR22951; CLATHRIN ASSEMBLY PROTEIN; 1.
DR PANTHER; PTHR22951:SF89; PHOSPHATIDYLINOSITOL-BINDING CLATHRIN ASSEMBLY PROTEIN LAP; 1.
DR Pfam; PF07651; ANTH; 1.
DR SMART; SM00273; ENTH; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR SUPFAM; SSF89009; GAT-like domain; 1.
DR PROSITE; PS50942; ENTH; 1.
PE 4: Predicted;
KW Coated pit {ECO:0000256|ARBA:ARBA00023176};
KW Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW Endocytosis {ECO:0000256|ARBA:ARBA00022583};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000091857}.
FT DOMAIN 24..161
FT /note="ENTH"
FT /evidence="ECO:0000259|PROSITE:PS50942"
FT REGION 328..350
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 561 AA; 62022 MW; 448425B8E67219ED CRC64;
MGTLQTWRKA YGALKDSTKV GLAHVNSDYA ELDVAIVKAT NHVECPPKER HLRKILVATS
AIRPRADVAY CIHALSRRLA KTHNWTVALK TLIVIHRLLR EGDHTFREEL LNFSQRGRIL
QLSNFKDDSS PIAWDCSAWV RTYALFLEER LECFRILKYD IEAERLPRPA EGQDKGYSRT
RDLDSEELLE QLPALQQLLY RLVGCRPEGA AVSNYVIQYA LALVLKESFK IYCAINDGII
NLVDKFFEMP RHEAVTALDV YKRAGQQAGS LSDFYEICKG LELARNFQFP VLREPPQSFL
TTMEEYIREA PRIVSIPSEP LLQLTYRPDE GPDEPEETIV PSDEPEPVPS DDVAVSNVEI
APPTPITPQS NMDTVDLLGL SYGAPDASAI EERNALALAI VPQDTAPTFN SGAGQAKDFD
PTGWELALVT TPSSNISSVN ERQLAGGLDS LTLNSLYDEA AYRAAQQPVY GSPALNPFEV
QDPFTMSNGI AAPSSVQMAA MGQQPPNPFG PYQPTYPQTM QQQNLIMGAT NPFGDTGLGT
FPVNPVAHPH PNNPFGSTGL L
//
