ID A0A2C9UCL6_MANES Unreviewed; 1092 AA.
AC A0A2C9UCL6;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=FYVE-type domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=MANES_15G041300 {ECO:0000313|EMBL:OAY28102.1};
OS Manihot esculenta (Cassava) (Jatropha manihot).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Manihoteae;
OC Manihot.
OX NCBI_TaxID=3983 {ECO:0000313|EMBL:OAY28102.1, ECO:0000313|Proteomes:UP000091857};
RN [1] {ECO:0000313|EMBL:OAY28102.1, ECO:0000313|Proteomes:UP000091857}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AM560-2 {ECO:0000313|Proteomes:UP000091857};
RC TISSUE=Leaf {ECO:0000313|EMBL:OAY28102.1};
RA Bredeson J.V., Prochnik S.E., Lyons J.B., Schmutz J., Grimwood J.,
RA Vrebalov J., Bart R.S., Amuge T., Ferguson M.E., Green R., Putnam N.,
RA Stites J., Rounsley S., Rokhsar D.S.;
RT "WGS assembly of Manihot esculenta.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CM004401; OAY28102.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2C9UCL6; -.
DR STRING; 3983.A0A2C9UCL6; -.
DR EnsemblPlants; OAY28102; OAY28102; MANES_15G041300.
DR Gramene; OAY28102; OAY28102; MANES_15G041300.
DR OMA; HNMTVAL; -.
DR OrthoDB; 551430at2759; -.
DR Proteomes; UP000091857; Chromosome lg15.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd00065; FYVE_like_SF; 1.
DR CDD; cd13365; PH_PLC_plant-like; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 2.130.10.30; Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II; 3.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR013591; Brevis_radix_dom.
DR InterPro; IPR027988; BRX_N.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR009091; RCC1/BLIP-II.
DR InterPro; IPR000408; Reg_chr_condens.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR22870; REGULATOR OF CHROMOSOME CONDENSATION; 1.
DR PANTHER; PTHR22870:SF352; REGULATOR OF CHROMOSOME CONDENSATION (RCC1) FAMILY WITH FYVE ZINC FINGER DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF08381; BRX; 1.
DR Pfam; PF13713; BRX_N; 1.
DR Pfam; PF01363; FYVE; 1.
DR Pfam; PF16457; PH_12; 1.
DR Pfam; PF00415; RCC1; 6.
DR PRINTS; PR00633; RCCNDNSATION.
DR SMART; SM00064; FYVE; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF50985; RCC1/BLIP-II; 1.
DR PROSITE; PS51514; BRX; 1.
DR PROSITE; PS00626; RCC1_2; 2.
DR PROSITE; PS50012; RCC1_3; 7.
DR PROSITE; PS50178; ZF_FYVE; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000091857};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT REPEAT 231..283
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 284..335
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 336..390
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 391..442
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 453..504
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 505..556
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 557..608
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT DOMAIN 613..675
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT DOMAIN 990..1045
FT /note="BRX"
FT /evidence="ECO:0000259|PROSITE:PS51514"
FT REGION 778..811
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 942..991
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1043..1092
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 814..890
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 942..986
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1092 AA; 118954 MW; F0F8A597926D4FB6 CRC64;
MADPVSYVNS ERDIEQALIT LKKGTQLIKY SRKGKPKFRA FRLSPDETAL IWLSHGEEKY
LRLSSVSRII PGQRTAVFRR YLRPEKDYLS FSLLYNNGDR SLDLICKDKL EAEVWLAGLK
ALIGKKSSRR TRSDISDLTE GGDFFQNGRP SSVSLEFSSS INHGRVSVDL GYRDTYFNSA
SSDVGSERAN MQLRTSGGDG FRISVSSTPS CSSGGSGPDD IELLGDVYVW GEVWSDGVSP
DGSTSSLPVK NDILIPKPLE SKIVLDVHQI ACGMHHVGLV TKQGEVFTWG EESGGRLGHG
TEMDFSCPRL VEFLAVTNVD FVACGEYHTC AVSSTGDLFT WGDGTQNAGL LGQGTDVSHW
IPKRVSGPLE GLQVLSVACG TWHSALATTN GKLFTFGDGT FGVLGHGDRE SVSFPKEVQL
LSGLKTIKVA CGVWHTAAIV EVMSQPGTTV SSRKLFTWGD GDKNRLGHGS KETYLLPTCV
SPLIDYNFHQ IACGHTMTVA LTTSGHVFAM GGTAYGQLGN PNSDGKVPSL VQDNLVGEFV
EEVSCGAYHI AVLTSRSEVY TWGRGANGQL GHGDTEDRRT PTLVETLRDR HVKNISCGSN
FTSSICIHKW VSGVDQSVCS GCRQAFGFTR KRHNCYNCGL VHCHACSSKK ALKAALAPTP
GKPHRVCDAC YAKLKAADAG NSNMNRKSTT PRRSVDIREK MDRGEVRASR VLLSPTTEPI
KYLEIKSFKP GTKSEVPSIV RASQVPSLLQ LKDVAFPSSL SAMQSSWKPT PSPVYQSGMN
FTQPSAANSR PASPYSRRPS PPRTSTAGFS RSVIDSLKKT NDILKQDMTK MQNQIKTFKQ
KCDVQDTQIQ KLQKQAKATA LLATSEATKS RVAKELVQSI TEQLKQMKEQ LPPDVHESEI
FKAMNSQIET FLNAYETSES SSLAESLGSS NLQDQRIEYQ ADTTRATDSS KNDGNVRRRP
SGSGSTEGIP QHISGNVTGT LESSSARREG ESIEQFEPGV YVTFIQRSDG VKLFKRVKFS
KRRFQEQQAE VWWKENKDRL LRRYSPTSNT ASTGSSSTPA EAPPSTAVSP SAPAESSTTA
AEDTSEAGPS ET
//
