ID   A0A2C9UCV2_MANES        Unreviewed;       770 AA.
AC   A0A2C9UCV2;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=PHO1 {ECO:0008006|Google:ProtNLM};
GN   ORFNames=MANES_15G043500 {ECO:0000313|EMBL:OAY28126.1};
OS   Manihot esculenta (Cassava) (Jatropha manihot).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Manihoteae;
OC   Manihot.
OX   NCBI_TaxID=3983 {ECO:0000313|EMBL:OAY28126.1, ECO:0000313|Proteomes:UP000091857};
RN   [1] {ECO:0000313|EMBL:OAY28126.1, ECO:0000313|Proteomes:UP000091857}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. AM560-2 {ECO:0000313|Proteomes:UP000091857};
RC   TISSUE=Leaf {ECO:0000313|EMBL:OAY28126.1};
RA   Bredeson J.V., Prochnik S.E., Lyons J.B., Schmutz J., Grimwood J.,
RA   Vrebalov J., Bart R.S., Amuge T., Ferguson M.E., Green R., Putnam N.,
RA   Stites J., Rounsley S., Rokhsar D.S.;
RT   "WGS assembly of Manihot esculenta.";
RL   Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the SYG1 (TC 2.A.94) family.
CC       {ECO:0000256|ARBA:ARBA00009665}.
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DR   EMBL; CM004401; OAY28126.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2C9UCV2; -.
DR   STRING; 3983.A0A2C9UCV2; -.
DR   EnsemblPlants; OAY28126; OAY28126; MANES_15G043500.
DR   Gramene; OAY28126; OAY28126; MANES_15G043500.
DR   OMA; NPYTWLF; -.
DR   OrthoDB; 1331193at2759; -.
DR   Proteomes; UP000091857; Chromosome lg15.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0005802; C:trans-Golgi network; IBA:GO_Central.
DR   GO; GO:0000822; F:inositol hexakisphosphate binding; IBA:GO_Central.
DR   GO; GO:0015114; F:phosphate ion transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0016036; P:cellular response to phosphate starvation; IBA:GO_Central.
DR   GO; GO:0006817; P:phosphate ion transport; IBA:GO_Central.
DR   CDD; cd14476; SPX_PHO1_like; 1.
DR   InterPro; IPR004342; EXS_C.
DR   InterPro; IPR034092; PHO1_SPX.
DR   InterPro; IPR004331; SPX_dom.
DR   PANTHER; PTHR48389; SPX DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR48389:SF1; SPX DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF03124; EXS; 1.
DR   Pfam; PF03105; SPX; 2.
DR   PROSITE; PS51380; EXS; 1.
DR   PROSITE; PS51382; SPX; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Phosphate transport {ECO:0000256|ARBA:ARBA00022592};
KW   Reference proteome {ECO:0000313|Proteomes:UP000091857};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        373..401
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        413..436
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        461..482
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        494..515
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        641..660
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        689..706
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          2..322
FT                   /note="SPX"
FT                   /evidence="ECO:0000259|PROSITE:PS51382"
FT   DOMAIN          579..770
FT                   /note="EXS"
FT                   /evidence="ECO:0000259|PROSITE:PS51380"
FT   REGION          158..192
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        163..192
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   770 AA;  89999 MW;  CA7D99C9D6CD4FCC CRC64;
     MVKFSKELEA QLIPEWKEAF VNYWQLKKHI KKIKLSKKPQ QPNKHDFGLS IFDFIPSFPI
     KFSLNFFRSD TKTEIIQVRS KTMDDDDGEI YHTELLQLFF QEDEIRVFFE RLDEELNKVN
     QFYKATESEF LQRGELLNKQ LQILFDLKQV LNNRRRKPVD TGVFNPSSWS SSHRNPGTIK
     ESNDNSGESS ETDEIIAVLE KNGVNLINSA TRSKTKKGNH KKMALRIDIP ASTPRRTISA
     FASMLCWEDL FNNPQNAAAP QHLINKKKIQ YAEKMIRGGF VELYRGLQLL KTYSSLNMVA
     FTKILKKFDK VSNQQTSASY LKAVKRSHFI SSDKVVRLMD EVESLFTKHF SNNDRKKAMK
     FLRPQQRKES HMVTFLIGLS TGCFLSLFSV YAFLAYMAGI FSPNVRRSYV ETIYPVFSVF
     ALLSLHLFMY GCNLFMWKST RINYNFIFEF QPSTALKYRD AFLISTTLMT SVVAALIIHL
     LLRASGFSPS HVDAIPGVLF LIFMALLICP FDFFYRPTRY CFIRVIRNII CSPLYKVLMV
     DFFMADQLTS QIPLMRHLES MACYLLAGTF RTHRYATCNS GRLYMELAYV ISFLPYYWRA
     MQCARRWFDE SDVNHLKNMG KYVSAMVAAG ARLTYSRQEN YLWFCIVLVS SAVATVYQLY
     WDFVKDWGLL NPKSKNPWLR DDLILKNKSI YYISIALNIV LRVVWVETMM QFRFNIVESR
     MLDFFLASLE VIRRGHWNFY RLENEHLNNV GKFRAVKTVP LPFRETDSDG
//