ID A0A2C9UKA2_MANES Unreviewed; 394 AA.
AC A0A2C9UKA2;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=Fructose-bisphosphate aldolase {ECO:0000256|ARBA:ARBA00013068, ECO:0000256|RuleBase:RU003994};
DE EC=4.1.2.13 {ECO:0000256|ARBA:ARBA00013068, ECO:0000256|RuleBase:RU003994};
GN ORFNames=MANES_14G108900 {ECO:0000313|EMBL:OAY31394.1};
OS Manihot esculenta (Cassava) (Jatropha manihot).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Manihoteae;
OC Manihot.
OX NCBI_TaxID=3983 {ECO:0000313|EMBL:OAY31394.1, ECO:0000313|Proteomes:UP000091857};
RN [1] {ECO:0000313|EMBL:OAY31394.1, ECO:0000313|Proteomes:UP000091857}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AM560-2 {ECO:0000313|Proteomes:UP000091857};
RC TISSUE=Leaf {ECO:0000313|EMBL:OAY31394.1};
RA Bredeson J.V., Prochnik S.E., Lyons J.B., Schmutz J., Grimwood J.,
RA Vrebalov J., Bart R.S., Amuge T., Ferguson M.E., Green R., Putnam N.,
RA Stites J., Rounsley S., Rokhsar D.S.;
RT "WGS assembly of Manihot esculenta.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-
CC phosphate + dihydroxyacetone phosphate; Xref=Rhea:RHEA:14729,
CC ChEBI:CHEBI:32966, ChEBI:CHEBI:57642, ChEBI:CHEBI:59776; EC=4.1.2.13;
CC Evidence={ECO:0000256|ARBA:ARBA00000441,
CC ECO:0000256|RuleBase:RU003994};
CC -!- PATHWAY: Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-
CC phosphate and glycerone phosphate from D-glucose: step 4/4.
CC {ECO:0000256|ARBA:ARBA00004714}.
CC -!- SIMILARITY: Belongs to the class I fructose-bisphosphate aldolase
CC family. {ECO:0000256|ARBA:ARBA00010387, ECO:0000256|RuleBase:RU003994}.
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DR EMBL; CM004400; OAY31394.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2C9UKA2; -.
DR STRING; 3983.A0A2C9UKA2; -.
DR EnsemblPlants; OAY31394; OAY31394; MANES_14G108900.
DR Gramene; OAY31394; OAY31394; MANES_14G108900.
DR OMA; CKPWAMS; -.
DR OrthoDB; 3595068at2759; -.
DR UniPathway; UPA00109; UER00183.
DR Proteomes; UP000091857; Chromosome lg14.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0004332; F:fructose-bisphosphate aldolase activity; IBA:GO_Central.
DR GO; GO:0030388; P:fructose 1,6-bisphosphate metabolic process; IBA:GO_Central.
DR GO; GO:0006096; P:glycolytic process; IBA:GO_Central.
DR CDD; cd00948; FBP_aldolase_I_a; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR029768; Aldolase_I_AS.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR000741; FBA_I.
DR NCBIfam; NF033379; FrucBisAld_I; 1.
DR PANTHER; PTHR11627; FRUCTOSE-BISPHOSPHATE ALDOLASE; 1.
DR PANTHER; PTHR11627:SF75; FRUCTOSE-BISPHOSPHATE ALDOLASE 3, CHLOROPLASTIC; 1.
DR Pfam; PF00274; Glycolytic; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
DR PROSITE; PS00158; ALDOLASE_CLASS_I; 1.
PE 3: Inferred from homology;
KW Glycolysis {ECO:0000256|RuleBase:RU003994};
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|RuleBase:RU003994};
KW Reference proteome {ECO:0000313|Proteomes:UP000091857};
KW Schiff base {ECO:0000256|ARBA:ARBA00023270}.
SQ SEQUENCE 394 AA; 42792 MW; EA05B3EA64E6A816 CRC64;
MACASFAKLN AASSSWIGQQ SFGQRPGSSS ARLTTRRVSL PIRASSYKDE LVQTAKSIAS
PGRGILAIDE SNATCGKRLA SIGLDNNEVN RQAYRQLLLT TPGLGEYISG AILFEETLYQ
STVDGKKFVD CLRDENIVPG IKVDKGLVPL PGSNNESWCQ GLDGLASRSA EYYKQGARFA
KWRTVVSIPC GPSALAVKEA AWGLARYAAI SQDNGLVPIV EPEILLDGDH GIERTLEVAE
KVWAEVFFYL AENNVVFEGI LLKPSMVTPG AEHKEKASPE TIAKYTLTML KRRVPPAVPG
IMFLSGGQSE VEATLNLNAM NQIPNPWHVS FSYARALQNT VLKTWQGRPE NVEAAQKALL
VRAKANSLAQ LGKYSGEGES EEAKKGMFVK GYTY
//
