ID A0A2C9UKX9_MANES Unreviewed; 471 AA.
AC A0A2C9UKX9;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=geranylgeranyl diphosphate reductase {ECO:0000256|ARBA:ARBA00012380};
DE EC=1.3.1.83 {ECO:0000256|ARBA:ARBA00012380};
DE AltName: Full=Geranylgeranyl reductase {ECO:0000256|ARBA:ARBA00033069};
GN ORFNames=MANES_14G078700 {ECO:0000313|EMBL:OAY31037.1};
OS Manihot esculenta (Cassava) (Jatropha manihot).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Manihoteae;
OC Manihot.
OX NCBI_TaxID=3983 {ECO:0000313|EMBL:OAY31037.1, ECO:0000313|Proteomes:UP000091857};
RN [1] {ECO:0000313|EMBL:OAY31037.1, ECO:0000313|Proteomes:UP000091857}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AM560-2 {ECO:0000313|Proteomes:UP000091857};
RC TISSUE=Leaf {ECO:0000313|EMBL:OAY31037.1};
RA Bredeson J.V., Prochnik S.E., Lyons J.B., Schmutz J., Grimwood J.,
RA Vrebalov J., Bart R.S., Amuge T., Ferguson M.E., Green R., Putnam N.,
RA Stites J., Rounsley S., Rokhsar D.S.;
RT "WGS assembly of Manihot esculenta.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=3 NADP(+) + phytyl diphosphate = geranylgeranyl diphosphate +
CC 3 H(+) + 3 NADPH; Xref=Rhea:RHEA:26229, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57533, ChEBI:CHEBI:57783, ChEBI:CHEBI:58349,
CC ChEBI:CHEBI:75434; EC=1.3.1.83;
CC Evidence={ECO:0000256|ARBA:ARBA00001640};
CC -!- PATHWAY: Porphyrin-containing compound metabolism.
CC {ECO:0000256|ARBA:ARBA00023444}.
CC -!- SIMILARITY: Belongs to the geranylgeranyl reductase family. ChlP
CC subfamily. {ECO:0000256|ARBA:ARBA00006632}.
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DR EMBL; CM004400; OAY31037.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2C9UKX9; -.
DR STRING; 3983.A0A2C9UKX9; -.
DR EnsemblPlants; OAY31037; OAY31037; MANES_14G078700.
DR Gramene; OAY31037; OAY31037; MANES_14G078700.
DR OMA; GMCRREV; -.
DR OrthoDB; 1032166at2759; -.
DR Proteomes; UP000091857; Chromosome lg14.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR GO; GO:0102067; F:geranylgeranyl diphosphate reductase activity; IEA:UniProtKB-EC.
DR GO; GO:0045550; F:geranylgeranyl reductase activity; IBA:GO_Central.
DR GO; GO:0015995; P:chlorophyll biosynthetic process; IBA:GO_Central.
DR GO; GO:0015979; P:photosynthesis; IEA:UniProtKB-KW.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR010253; BchP_ChlP_pln/prok.
DR InterPro; IPR002938; FAD-bd.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR011777; Geranylgeranyl_Rdtase_fam.
DR InterPro; IPR011774; Geranylgeranyl_Rdtase_pln/cyn.
DR NCBIfam; TIGR02023; BchP-ChlP; 1.
DR NCBIfam; TIGR02028; ChlP; 1.
DR NCBIfam; TIGR02032; GG-red-SF; 1.
DR PANTHER; PTHR42685; GERANYLGERANYL DIPHOSPHATE REDUCTASE; 1.
DR PANTHER; PTHR42685:SF4; GERANYLGERANYL DIPHOSPHATE REDUCTASE, CHLOROPLASTIC; 1.
DR Pfam; PF01494; FAD_binding_3; 1.
DR PRINTS; PR00420; RNGMNOXGNASE.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW Chlorophyll biosynthesis {ECO:0000256|ARBA:ARBA00023171};
KW Photosynthesis {ECO:0000256|ARBA:ARBA00022531};
KW Reference proteome {ECO:0000313|Proteomes:UP000091857}.
FT DOMAIN 57..87
FT /note="FAD-binding"
FT /evidence="ECO:0000259|Pfam:PF01494"
SQ SEQUENCE 471 AA; 52005 MW; EF3330B87B4BD52E CRC64;
MTSSIAFKTF TGLRHSSAEP STLQNKVPSV SSPNHCRRRL QITAGKFSPK VQNRNLRVAV
IGGGPAGGAA AETLAKGGIE TYLIERKLDN CKPCGGAIPL CMVGEFDLPL DIIDRKVTKM
KMISPSNIAV DIGRTLKPHE YIGMVRREVL DSYLRERAAT NGANVINGLF LKMDIPKGGR
GSETAPYVLH YTEYNGKVGG AGQKKTLEVD AVIGADGANS RVAKSIGAGD YDYAIAFQER
IKIPDDKMVY YENLAEMYVG DDVSPDFYGW VFPKCDHVAV GTGTVTHKGD IKKFQLATRN
RAKDKILGGK IIRVEAHPIP EHPRPRRLLD RVALVGDAAG YVTKCSGEGI YFAAKSGRMC
AEAIVEGSEN GKRMVDESDL RKYLEKWDKT YWPTYKVLDV LQKVFYRSNP AREAFVEMCA
DEYVQKMTFD SYLYKRVVPG NPLDDLKLAF NTIGSLVRAN ALRKEMNKLS V
//
