ID   A0A2C9UPA5_MANES        Unreviewed;       646 AA.
AC   A0A2C9UPA5;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=STAS domain-containing protein {ECO:0000259|PROSITE:PS50801};
GN   ORFNames=MANES_14G167500 {ECO:0000313|EMBL:OAY32117.1};
OS   Manihot esculenta (Cassava) (Jatropha manihot).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Manihoteae;
OC   Manihot.
OX   NCBI_TaxID=3983 {ECO:0000313|EMBL:OAY32117.1, ECO:0000313|Proteomes:UP000091857};
RN   [1] {ECO:0000313|EMBL:OAY32117.1, ECO:0000313|Proteomes:UP000091857}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. AM560-2 {ECO:0000313|Proteomes:UP000091857};
RC   TISSUE=Leaf {ECO:0000313|EMBL:OAY32117.1};
RA   Bredeson J.V., Prochnik S.E., Lyons J.B., Schmutz J., Grimwood J.,
RA   Vrebalov J., Bart R.S., Amuge T., Ferguson M.E., Green R., Putnam N.,
RA   Stites J., Rounsley S., Rokhsar D.S.;
RT   "WGS assembly of Manihot esculenta.";
RL   Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC       ECO:0000256|RuleBase:RU362052}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU362052}.
CC   -!- SIMILARITY: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
CC       {ECO:0000256|RuleBase:RU362052}.
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DR   EMBL; CM004400; OAY32117.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2C9UPA5; -.
DR   STRING; 3983.A0A2C9UPA5; -.
DR   EnsemblPlants; OAY32117; OAY32117; MANES_14G167500.
DR   Gramene; OAY32117; OAY32117; MANES_14G167500.
DR   OMA; RLRLGCW; -.
DR   OrthoDB; 2880581at2759; -.
DR   Proteomes; UP000091857; Chromosome lg14.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008509; F:monoatomic anion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0008271; F:secondary active sulfate transmembrane transporter activity; IEA:InterPro.
DR   CDD; cd07042; STAS_SulP_like_sulfate_transporter; 1.
DR   Gene3D; 3.30.750.24; STAS domain; 1.
DR   InterPro; IPR018045; S04_transporter_CS.
DR   InterPro; IPR011547; SLC26A/SulP_dom.
DR   InterPro; IPR001902; SLC26A/SulP_fam.
DR   InterPro; IPR002645; STAS_dom.
DR   InterPro; IPR036513; STAS_dom_sf.
DR   NCBIfam; TIGR00815; sulP; 1.
DR   PANTHER; PTHR11814:SF271; STAS DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR11814; SULFATE TRANSPORTER; 1.
DR   Pfam; PF01740; STAS; 1.
DR   Pfam; PF00916; Sulfate_transp; 1.
DR   SUPFAM; SSF52091; SpoIIaa-like; 1.
DR   PROSITE; PS01130; SLC26A; 1.
DR   PROSITE; PS50801; STAS; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362052};
KW   Reference proteome {ECO:0000313|Proteomes:UP000091857};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU362052};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU362052}; Transport {ECO:0000256|RuleBase:RU362052}.
FT   TRANSMEM        136..153
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362052"
FT   TRANSMEM        165..186
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362052"
FT   TRANSMEM        198..216
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362052"
FT   TRANSMEM        246..263
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362052"
FT   TRANSMEM        275..295
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362052"
FT   TRANSMEM        332..355
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362052"
FT   TRANSMEM        367..386
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362052"
FT   TRANSMEM        406..424
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362052"
FT   TRANSMEM        431..453
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362052"
FT   TRANSMEM        465..488
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362052"
FT   DOMAIN          516..639
FT                   /note="STAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50801"
SQ   SEQUENCE   646 AA;  71180 MW;  24A1A68D035A0FEC CRC64;
     MEINNNESSS FHRHSESLPC VHKVGLPPKQ NLFQEITAAV KETLFADDPL RQFKDQTRSR
     KFVLGIQTLF PIFEWGRDYS FSKFKGDLVA GLTIASLCIP QDIGYSQLAN LKPQYGLYSS
     FVPPLIYAFM GSSRDIAIGP VAVVSLVLGS LLQNEIDPSK DPVNYLHLTF TATFFAGITQ
     VTLGFFRLGF LIDFLSHAAI VGFMAGAAIT IALQQLKELL GIAHFTRKTD IVSVMRSVWT
     TVDHGWNWQT IVIGVSFLVL LLLAKQIAKK KKKLFWVAAI APLVSVILST LIVYVTHANK
     HGVKIVNEIK RGVNPPSVNE IFFSGEYLGK GFRIGVVAGM IALTEAIAIG RTFAAMKDYQ
     IDGNKEMVAL GTMNVVGSMT SCYVATGSFS RSAVNFMAGC NTAVSNIVMS LVVLLTLELI
     TPLFKYTPKA IISSIIISAV IGLIDIEAVI LIWKVDKFDF VACMGAFFGV VFKSVEIGLL
     IAVSISFAKI LLQVTRPRTA ILGKLPRTTV YRNIQQYPEA SKVPGILIVR VDSAIYFSNS
     NYIKERILRW LTDEEEHLEE NNLPRIQFLI VEMSPVTDID TSGIHALKEL HSSLQKRNVE
     LVLANPGPVV VNKLHASSFT ELIGEDNIFL TVADAVHTCA PKMEEV
//