ID A0A2C9UYS0_MANES Unreviewed; 992 AA.
AC A0A2C9UYS0;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE RecName: Full=Exportin-T {ECO:0000256|ARBA:ARBA00018928, ECO:0000256|RuleBase:RU366037};
DE AltName: Full=Exportin(tRNA) {ECO:0000256|ARBA:ARBA00029784, ECO:0000256|RuleBase:RU366037};
DE AltName: Full=tRNA exportin {ECO:0000256|ARBA:ARBA00032199, ECO:0000256|RuleBase:RU366037};
GN ORFNames=MANES_11G019400 {ECO:0000313|EMBL:OAY36408.1};
OS Manihot esculenta (Cassava) (Jatropha manihot).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Manihoteae;
OC Manihot.
OX NCBI_TaxID=3983 {ECO:0000313|EMBL:OAY36408.1, ECO:0000313|Proteomes:UP000091857};
RN [1] {ECO:0000313|EMBL:OAY36408.1, ECO:0000313|Proteomes:UP000091857}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AM560-2 {ECO:0000313|Proteomes:UP000091857};
RC TISSUE=Leaf {ECO:0000313|EMBL:OAY36408.1};
RA Bredeson J.V., Prochnik S.E., Lyons J.B., Schmutz J., Grimwood J.,
RA Vrebalov J., Bart R.S., Amuge T., Ferguson M.E., Green R., Putnam N.,
RA Stites J., Rounsley S., Rokhsar D.S.;
RT "WGS assembly of Manihot esculenta.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: tRNA nucleus export receptor which facilitates tRNA
CC translocation across the nuclear pore complex.
CC {ECO:0000256|RuleBase:RU366037}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496,
CC ECO:0000256|RuleBase:RU366037}. Nucleus
CC {ECO:0000256|RuleBase:RU366037}. Note=Shuttles between the nucleus and
CC the cytoplasm. {ECO:0000256|RuleBase:RU366037}.
CC -!- SIMILARITY: Belongs to the exportin family.
CC {ECO:0000256|RuleBase:RU366037}.
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DR EMBL; CM004397; OAY36408.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2C9UYS0; -.
DR STRING; 3983.A0A2C9UYS0; -.
DR EnsemblPlants; OAY36408; OAY36408; MANES_11G019400.
DR Gramene; OAY36408; OAY36408; MANES_11G019400.
DR OMA; HEMFLFG; -.
DR OrthoDB; 2546268at2759; -.
DR Proteomes; UP000091857; Chromosome lg11.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0016363; C:nuclear matrix; IBA:GO_Central.
DR GO; GO:0005643; C:nuclear pore; IBA:GO_Central.
DR GO; GO:0005049; F:nuclear export signal receptor activity; IEA:EnsemblPlants.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0000049; F:tRNA binding; IBA:GO_Central.
DR GO; GO:0009908; P:flower development; IEA:EnsemblPlants.
DR GO; GO:0010014; P:meristem initiation; IEA:EnsemblPlants.
DR GO; GO:0071528; P:tRNA re-export from nucleus; IBA:GO_Central.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR013598; Exportin-1/Importin-b-like.
DR InterPro; IPR045546; Exportin-T_C.
DR InterPro; IPR040017; XPOT.
DR PANTHER; PTHR15952:SF11; EXPORTIN-T; 1.
DR PANTHER; PTHR15952; EXPORTIN-T/LOS1; 1.
DR Pfam; PF19282; Exportin-T; 1.
DR Pfam; PF08389; Xpo1; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|RuleBase:RU366037};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU366037};
KW Reference proteome {ECO:0000313|Proteomes:UP000091857};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|RuleBase:RU366037};
KW Transport {ECO:0000256|RuleBase:RU366037};
KW tRNA-binding {ECO:0000256|ARBA:ARBA00022555,
KW ECO:0000256|RuleBase:RU366037}.
FT DOMAIN 107..259
FT /note="Exportin-1/Importin-beta-like"
FT /evidence="ECO:0000259|Pfam:PF08389"
FT DOMAIN 323..980
FT /note="Exportin-T C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19282"
SQ SEQUENCE 992 AA; 111960 MW; E82C87A1B120D0E2 CRC64;
MDDLEKAILI SFDESGTIDS PLKSQAVAFC QQIKETPTIC RICIEKLCFC NLIQVQFWCL
QTLHEVIRVK YALLSLEEKD FVRKSVFSMC CFDVIDDSNA VRVLEGPTFI KNKLAQVLVT
LIYFEYPAIW SSVFVDFLHR LSKGAVVIDM FCRVLNALDD ELISLDYPRT PEELGVAGQV
KDAMRQQCVA QIVRAWFDIV SMYRNSDPDL CSSVLDSMRR YISWIDIGLI VNDMFVPLLF
ELMLVDGEFE QLQGAAAGCV LAVVSKRMDP QSKLAILRSL QVSRVFALVT GDSDSELVSK
IAALITGYAV EVLECYKRAS TEDAKAVSLE LLNEVLPSVF YVMQNCEVDT AFSIVQFLSG
YVATMKSLSP LREKQAHYVG QILEVIRTQI RYDPMYRDNL DSFDKIGREE EDRMVEYRKD
LFVLLRSVGR VAPDTTQVFI RNSLASAVAS SAEINVEEVE AALSLLYALG ESLSDEAMRA
GSGLLSELVP MLLSTRFPCH SNRLVALVYL ETMTRYMKFV LENTQYIPLA LAAFLDERGI
HHPNIHVSRR ASYLFMRVVK LLKAKLVPFI ETILQSLQDT VARFTSMDYN YTPYEFSGPE
DGSHIFEAIG LLVGMEDVPL QKQADYLSSL LTPLCQQVEI LLMNAKLADA EESPAKIVNI
QQIIVAINAL SKGFSERLVT ASRPAIGLMF KQTLDVLLQI LVVFPKVEPL RIKVTSFIHR
MVDTLGASVF PYLPKALEQL LVECEPKEMV GFLVLLNQLI CKFNISVHDI LEEIFPAIAG
RICNVIPKDA YPSGPGGNTE EIRELQELQK TVYTFLHVIT THDLSSIFLS PKSRGYLDSL
MQLLLYAACN HKDILVRKSC VQIFNRLIKD WCAKPYGEEK VPGFQSFIIE AFATNCCLYS
VLDKSFDFQD ANTQLVLFGE IVQAQKLLYE KFGNDFVLHF VSKGFPSAHC PQDLAQQYCQ
RLQGSDFKAL KSFYQSLVEN LRLQQNGSLV FR
//
