ID   A0A2C9V4W1_MANES        Unreviewed;       286 AA.
AC   A0A2C9V4W1;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=Phorbol-ester/DAG-type domain-containing protein {ECO:0000259|PROSITE:PS50081};
GN   ORFNames=MANES_10G031100 {ECO:0000313|EMBL:OAY38638.1};
OS   Manihot esculenta (Cassava) (Jatropha manihot).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Manihoteae;
OC   Manihot.
OX   NCBI_TaxID=3983 {ECO:0000313|EMBL:OAY38638.1, ECO:0000313|Proteomes:UP000091857};
RN   [1] {ECO:0000313|EMBL:OAY38638.1, ECO:0000313|Proteomes:UP000091857}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. AM560-2 {ECO:0000313|Proteomes:UP000091857};
RC   TISSUE=Leaf {ECO:0000313|EMBL:OAY38638.1};
RA   Bredeson J.V., Prochnik S.E., Lyons J.B., Schmutz J., Grimwood J.,
RA   Vrebalov J., Bart R.S., Amuge T., Ferguson M.E., Green R., Putnam N.,
RA   Stites J., Rounsley S., Rokhsar D.S.;
RT   "WGS assembly of Manihot esculenta.";
RL   Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CM004396; OAY38638.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2C9V4W1; -.
DR   STRING; 3983.A0A2C9V4W1; -.
DR   EnsemblPlants; OAY38638; OAY38638; MANES_10G031100.
DR   Gramene; OAY38638; OAY38638; MANES_10G031100.
DR   OrthoDB; 333694at2759; -.
DR   Proteomes; UP000091857; Chromosome lg10.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.60.20; -; 1.
DR   InterPro; IPR046349; C1-like_sf.
DR   InterPro; IPR004146; DC1.
DR   InterPro; IPR002219; PE/DAG-bd.
DR   PANTHER; PTHR46477; CYSTEINE/HISTIDINE-RICH C1 DOMAIN FAMILY PROTEIN; 1.
DR   PANTHER; PTHR46477:SF26; PHORBOL-ESTER_DAG-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF03107; C1_2; 2.
DR   SUPFAM; SSF57889; Cysteine-rich domain; 2.
DR   PROSITE; PS50081; ZF_DAG_PE_2; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000091857};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   TRANSMEM        250..271
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          14..61
FT                   /note="Phorbol-ester/DAG-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50081"
FT   REGION          185..244
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        185..200
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        207..230
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   286 AA;  31935 MW;  50CE1D01E61A0932 CRC64;
     MPPITDIKHR SHPAHDLKLS HPATPYICDG CKEIGYGICY RCRECRFYLH KECAIPHSPT
     YHHLFKGSKF DFYRRSPTSG GRICDACGKD VNGFLYHCSS TGYDMHPNCA KLPLILNGEG
     LTLELKGKAS ACQKCRVSGR RSNGWSYVSS CGKYCLHVAC VKEMIIEAWE KKYFNLQKGH
     EINRNHLKLP SKESKNGRVI TRGRGRSSSP GRRDGRTEKE GKRRYSSCGR SSNNREKITG
     RNAGRNPSMI WLNTGVTVLG ILLSAFLGVP ITPLASAAVL LAKNLF
//