ID A0A2C9VH49_MANES Unreviewed; 679 AA.
AC A0A2C9VH49;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=RING-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012483};
DE EC=2.3.2.27 {ECO:0000256|ARBA:ARBA00012483};
GN ORFNames=MANES_08G173500 {ECO:0000313|EMBL:OAY44706.1};
OS Manihot esculenta (Cassava) (Jatropha manihot).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Manihoteae;
OC Manihot.
OX NCBI_TaxID=3983 {ECO:0000313|EMBL:OAY44706.1, ECO:0000313|Proteomes:UP000091857};
RN [1] {ECO:0000313|EMBL:OAY44706.1, ECO:0000313|Proteomes:UP000091857}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AM560-2 {ECO:0000313|Proteomes:UP000091857};
RC TISSUE=Leaf {ECO:0000313|EMBL:OAY44706.1};
RA Bredeson J.V., Prochnik S.E., Lyons J.B., Schmutz J., Grimwood J.,
RA Vrebalov J., Bart R.S., Amuge T., Ferguson M.E., Green R., Putnam N.,
RA Stites J., Rounsley S., Rokhsar D.S.;
RT "WGS assembly of Manihot esculenta.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC EC=2.3.2.27; Evidence={ECO:0000256|ARBA:ARBA00000900};
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
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DR EMBL; CM004394; OAY44706.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2C9VH49; -.
DR EnsemblPlants; OAY44706; OAY44706; MANES_08G173500.
DR Gramene; OAY44706; OAY44706; MANES_08G173500.
DR OMA; VPAYKKR; -.
DR OrthoDB; 5489991at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000091857; Chromosome lg8.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd16664; RING-Ubox_PUB; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000225; Armadillo.
DR InterPro; IPR045210; RING-Ubox_PUB.
DR InterPro; IPR003613; Ubox_domain.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR23315; U BOX DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR23315:SF63; U-BOX DOMAIN-CONTAINING PROTEIN 16; 1.
DR Pfam; PF04564; U-box; 1.
DR SMART; SM00504; Ubox; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50176; ARM_REPEAT; 1.
DR PROSITE; PS51698; U_BOX; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000091857};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 267..341
FT /note="U-box"
FT /evidence="ECO:0000259|PROSITE:PS51698"
FT REPEAT 409..455
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
SQ SEQUENCE 679 AA; 75208 MW; FC06CF757C25FBF1 CRC64;
MTVSPQIFPP RKRWPSAGAF LAPSFSHHKL LHSLLILSQE ISSLNPISFL LKPNSLSVIR
KTSLLAIFFD ELLRNQIPFP SSTFLCFEEM YILLQRVKNL MEDCANGSRM WLLIQAESVV
SSFHELTLQL STLLDIFPLE HVDLSDDIQE LFTLIRKQCF QAKCSLDPSD YNLRHKVLTM
LDRIKKEIVP DHSKLAEIFD KLGLQNSSSC KEEMESLEDE MQNQIDHKSK SEVVALIGLV
RYAKCVLYGA STPTSDHGRE KVVSEAIVPP DFRCPISLEL MRDPVVLATG QTYNRESITL
WIESGHNTCP KTGQTLSHTN LISNLALKNL IGMWCREQKI PFESMENNQK LDGVMRNKAA
IAATKMMVSF FVNELSISQS LEAANGVVYE LRTLAKTNSD GRAYMAEVGV IPLLVRYLGS
DVGSELPNLQ VNAVTAILNL SILEANKTRI MEIDGVLNGV IEVLRSGATW EAKANAAATI
FSVSGVHSYR KQLGRKTRVI KGLMDLAKSG NMCSKKDALM AILSLAWDRE TIGRLVEAGV
VETVMEVVNV LPEEAVTILE MVVKKGGILA TAAAYNAIKK LGMLLREGSD AARESAMATL
VTICRKGGSE MVAELASICE IERIIWELMG SGTIRSRRKA ATLLRIIRRW AASLDGEFVD
MNTTATAIIT SSSRPAFAR
//
