ID A0A2C9VKP3_MANES Unreviewed; 398 AA.
AC A0A2C9VKP3;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE RecName: Full=Lipase {ECO:0000256|PIRNR:PIRNR000862};
GN ORFNames=MANES_07G070900 {ECO:0000313|EMBL:OAY45554.1};
OS Manihot esculenta (Cassava) (Jatropha manihot).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Manihoteae;
OC Manihot.
OX NCBI_TaxID=3983 {ECO:0000313|EMBL:OAY45554.1, ECO:0000313|Proteomes:UP000091857};
RN [1] {ECO:0000313|EMBL:OAY45554.1, ECO:0000313|Proteomes:UP000091857}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AM560-2 {ECO:0000313|Proteomes:UP000091857};
RC TISSUE=Leaf {ECO:0000313|EMBL:OAY45554.1};
RA Bredeson J.V., Prochnik S.E., Lyons J.B., Schmutz J., Grimwood J.,
RA Vrebalov J., Bart R.S., Amuge T., Ferguson M.E., Green R., Putnam N.,
RA Stites J., Rounsley S., Rokhsar D.S.;
RT "WGS assembly of Manihot esculenta.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the AB hydrolase superfamily. Lipase family.
CC {ECO:0000256|ARBA:ARBA00010701, ECO:0000256|PIRNR:PIRNR000862}.
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DR EMBL; CM004393; OAY45554.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2C9VKP3; -.
DR STRING; 3983.A0A2C9VKP3; -.
DR EnsemblPlants; OAY45554; OAY45554; MANES_07G070900.
DR Gramene; OAY45554; OAY45554; MANES_07G070900.
DR OrthoDB; 1214460at2759; -.
DR Proteomes; UP000091857; Chromosome lg7.
DR GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR006693; AB_hydrolase_lipase.
DR InterPro; IPR025483; Lipase_euk.
DR PANTHER; PTHR11005:SF100; LIPASE-RELATED; 1.
DR PANTHER; PTHR11005; LYSOSOMAL ACID LIPASE-RELATED; 1.
DR Pfam; PF04083; Abhydro_lipase; 1.
DR PIRSF; PIRSF000862; Steryl_ester_lip; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|PIRNR:PIRNR000862};
KW Lipid degradation {ECO:0000256|PIRNR:PIRNR000862};
KW Lipid metabolism {ECO:0000256|PIRNR:PIRNR000862};
KW Reference proteome {ECO:0000313|Proteomes:UP000091857};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..398
FT /note="Lipase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012135331"
FT DOMAIN 38..96
FT /note="Partial AB-hydrolase lipase"
FT /evidence="ECO:0000259|Pfam:PF04083"
FT ACT_SITE 172
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR000862-1"
FT ACT_SITE 340
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR000862-1"
FT ACT_SITE 369
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR000862-1"
SQ SEQUENCE 398 AA; 44715 MW; 423377B29DB56F60 CRC64;
MGMTILAIIS LLIFTTSGEF TTDEANLRRR SAGETLCSKL IEPAGYPCTE HTIQTKDGYL
LALQRVSSPN GNIRLQRGPP VLLQHGLFMA GDAWFLDSPE QSLGYILARQ GFDVWVGNVR
GTFWSYGHVS LSEKDKNFWD WSWQELALCD LSAMMHHIYS TTNSKILVVG HSQGTIMSLA
ALTQPNIAEM VEAAALLCPI SYLEHISAPL VLRMVGLHLD QMVLAMGIHQ LNFRSEVLIN
LLDSMCDGHV DCDDLLTSMT GQNCCLNNSR VDNFLEYEPH PSSVKNLRHL FQMIRQGTFS
QYDYGIFKNL KLYGQVKPPA FDLSQIPKSL PLWMGYGGYD ALADVADVEH TLKELQTKPE
LLYLENYGHL DFLMSVHGKE DVFDHMIRFF RSLGKSSA
//
