ID A0A2C9VQX8_MANES Unreviewed; 796 AA.
AC A0A2C9VQX8;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Histidine kinase/HSP90-like ATPase domain-containing protein {ECO:0000259|SMART:SM00387};
GN ORFNames=MANES_06G078500 {ECO:0000313|EMBL:OAY47426.1};
OS Manihot esculenta (Cassava) (Jatropha manihot).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Manihoteae;
OC Manihot.
OX NCBI_TaxID=3983 {ECO:0000313|EMBL:OAY47426.1, ECO:0000313|Proteomes:UP000091857};
RN [1] {ECO:0000313|EMBL:OAY47426.1, ECO:0000313|Proteomes:UP000091857}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AM560-2 {ECO:0000313|Proteomes:UP000091857};
RC TISSUE=Leaf {ECO:0000313|EMBL:OAY47426.1};
RA Bredeson J.V., Prochnik S.E., Lyons J.B., Schmutz J., Grimwood J.,
RA Vrebalov J., Bart R.S., Amuge T., Ferguson M.E., Green R., Putnam N.,
RA Stites J., Rounsley S., Rokhsar D.S.;
RT "WGS assembly of Manihot esculenta.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the heat shock protein 90 family.
CC {ECO:0000256|ARBA:ARBA00008239}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CM004392; OAY47426.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2C9VQX8; -.
DR STRING; 3983.A0A2C9VQX8; -.
DR EnsemblPlants; OAY47426; OAY47426; MANES_06G078500.
DR Gramene; OAY47426; OAY47426; MANES_06G078500.
DR OMA; QYSEFVH; -.
DR OrthoDB; 547579at2759; -.
DR Proteomes; UP000091857; Chromosome lg6.
DR GO; GO:0009570; C:chloroplast stroma; IBA:GO_Central.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0048471; C:perinuclear region of cytoplasm; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0032991; C:protein-containing complex; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR GO; GO:0051082; F:unfolded protein binding; IBA:GO_Central.
DR GO; GO:0034605; P:cellular response to heat; IBA:GO_Central.
DR GO; GO:0006457; P:protein folding; IBA:GO_Central.
DR GO; GO:0050821; P:protein stabilization; IBA:GO_Central.
DR CDD; cd16927; HATPase_Hsp90-like; 1.
DR Gene3D; 3.30.230.80; -; 1.
DR Gene3D; 3.40.50.11260; -; 1.
DR Gene3D; 1.20.120.790; Heat shock protein 90, C-terminal domain; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR HAMAP; MF_00505; HSP90; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR019805; Heat_shock_protein_90_CS.
DR InterPro; IPR037196; HSP90_C.
DR InterPro; IPR001404; Hsp90_fam.
DR InterPro; IPR020575; Hsp90_N.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR PANTHER; PTHR11528; HEAT SHOCK PROTEIN 90 FAMILY MEMBER; 1.
DR PANTHER; PTHR11528:SF54; HEAT SHOCK PROTEIN 90-5, CHLOROPLASTIC; 1.
DR Pfam; PF13589; HATPase_c_3; 1.
DR Pfam; PF00183; HSP90; 1.
DR PIRSF; PIRSF002583; Hsp90; 1.
DR PRINTS; PR00775; HEATSHOCK90.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF110942; HSP90 C-terminal domain; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR PROSITE; PS00298; HSP90; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000091857}.
FT DOMAIN 107..269
FT /note="Histidine kinase/HSP90-like ATPase"
FT /evidence="ECO:0000259|SMART:SM00387"
FT REGION 303..324
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 754..796
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 781..796
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 796 AA; 90333 MW; F02CEA34506BA404 CRC64;
MAPVLSRSLT AASLVSLPSS TPFSRKHLGS KSFALRSPFL PQNNGLKKGF SCTGLNWKLE
RRNNRIAVRC EAAVAEKEAA DTSGEKFEYQ AEVSRLLDLI VHSLYSHKEV FLRELVSNAS
DALDKLRFLS VTEPSLLGDA GDLEIRIKPD PDNGTITITD TGIGMTKEEL VDCLGTIAQS
GTSKFLKALK ENKDHGADNG LIGQFGVGFY SAFLVAEKVV VSTKSPRSDK QYVWEAVADS
SSYVIKEESD PEKLLRRGTQ ITLYLREDDK YEFSDPARIQ GLVKNYSQFV SFPIYTWQEK
SRTVEVEEEE EPKEGEEAKP EDEKKKKTKT EKYWDWELAN ETKPIWMRNS KEVEKDEYHE
FYKKTFNEFM DPIAYTHFTT EGEVEFRSVL YVPGMGPLNN EEVINPKTKN IRLYVKRVFI
SDDFDGELFP RYLSFVKGVV DSDDLPLNVS REILQESRIV RIMRKRLVRK TFDMIQELSE
SENKEDYKKF WENFGRFLKL GCIEDTGNHK RITPLLRFYT SKSEDELTTL DDYVENMGEN
QKAIYYLATD SLKSAKSAPF LEKLVQKGIE VLYLIEPIDE VAIQNLQTYK EKKFVDISKE
DLELGDEDEV KERETKQEFN LLCDWIKQQL GDKVAKVQVS KRLSSSPCVL VSGKFGWSAN
MERLMKAQAL GDTSSLEFMR GRRILEINPD HPIIKDLSAA CKNAPDSGDA TRAVDLLYDT
ALISSGFAPD SPAELGNKIY EMMAIALGGR WGRSEDDEAE TVDNNAAESV ANADEATETE
VVEPSEVRAE SDPWND
//
