ID A0A2C9VRT2_MANES Unreviewed; 806 AA.
AC A0A2C9VRT2;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=ADP-ribosylation factor GTPase-activating protein AGD1 {ECO:0008006|Google:ProtNLM};
GN ORFNames=MANES_06G126100 {ECO:0000313|EMBL:OAY48031.1};
OS Manihot esculenta (Cassava) (Jatropha manihot).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Manihoteae;
OC Manihot.
OX NCBI_TaxID=3983 {ECO:0000313|EMBL:OAY48031.1, ECO:0000313|Proteomes:UP000091857};
RN [1] {ECO:0000313|EMBL:OAY48031.1, ECO:0000313|Proteomes:UP000091857}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AM560-2 {ECO:0000313|Proteomes:UP000091857};
RC TISSUE=Leaf {ECO:0000313|EMBL:OAY48031.1};
RA Bredeson J.V., Prochnik S.E., Lyons J.B., Schmutz J., Grimwood J.,
RA Vrebalov J., Bart R.S., Amuge T., Ferguson M.E., Green R., Putnam N.,
RA Stites J., Rounsley S., Rokhsar D.S.;
RT "WGS assembly of Manihot esculenta.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CM004392; OAY48031.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2C9VRT2; -.
DR STRING; 3983.A0A2C9VRT2; -.
DR EnsemblPlants; OAY48031; OAY48031; MANES_06G126100.
DR Gramene; OAY48031; OAY48031; MANES_06G126100.
DR Proteomes; UP000091857; Chromosome lg6.
DR GO; GO:0030139; C:endocytic vesicle; IEA:EnsemblPlants.
DR GO; GO:0005886; C:plasma membrane; IEA:EnsemblPlants.
DR GO; GO:0035618; C:root hair; IEA:EnsemblPlants.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0007010; P:cytoskeleton organization; IEA:EnsemblPlants.
DR GO; GO:0048768; P:root hair cell tip growth; IEA:EnsemblPlants.
DR CDD; cd08204; ArfGap; 1.
DR CDD; cd07606; BAR_SFC_plant; 1.
DR CDD; cd13250; PH_ACAP; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR045258; ACAP1/2/3-like.
DR InterPro; IPR035670; AGD1/2/3/4_BAR_plant.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR037278; ARFGAP/RecO.
DR InterPro; IPR001164; ArfGAP_dom.
DR InterPro; IPR038508; ArfGAP_dom_sf.
DR InterPro; IPR004148; BAR_dom.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR23180:SF405; ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN AGD1-LIKE; 1.
DR PANTHER; PTHR23180; CENTAURIN/ARF; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF01412; ArfGap; 1.
DR Pfam; PF16746; BAR_3; 1.
DR Pfam; PF00169; PH; 1.
DR PRINTS; PR00405; REVINTRACTNG.
DR SMART; SM00248; ANK; 2.
DR SMART; SM00105; ArfGap; 1.
DR SMART; SM00721; BAR; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 2.
DR PROSITE; PS50088; ANK_REPEAT; 2.
DR PROSITE; PS50115; ARFGAP; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000091857};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00288}.
FT DOMAIN 292..429
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 500..647
FT /note="Arf-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50115"
FT REPEAT 716..748
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 749..781
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
SQ SEQUENCE 806 AA; 90446 MW; BDD38D1355910AA9 CRC64;
MHFSKLDDSP MFRQQMQCLE ESSELLRGRC LKFIKGCRKY TEGLGEGYDG DVAFASALET
FGGGHNDPIC VAFGGPVMNK FTIALREIGT YKEVLRSQVE HILNDRLLQF VNVDLQDIKE
ARKRFDKASL IYDQARDKFL SLRKSTRMDV ATSIEEELYN ARSSFEQARF HLVSALSIVE
AKKRFEFLEA VSGTMDAHIR YFKQGYELLH QLEPFINQVL AYAQQSRECS NYEQAALNER
VQEYVRQIDR ESKHNLNGGV GSPSGDGLRL FARSSQKVIE AVMQSAAKGK VQTIRQGYLS
KRSSNLRGDW KRRFFVLDSQ GMLYYYRKPF NWTSGSGSQS SVQRNASADN SPGLLSRWLS
SHYHGGVHDE KSVARHTVNL LTSTIKADAD QSDLRFCFRI ISPVKVYTLQ AENALDQVDW
IEKITGVITS LLSFQTSERH LSTSHMGIGD HHSVSDSSSM ADSPDIDHAE IEEFASNNMT
TRCCLNSKNS QQQECCVRSE KPIDVLRKVP GNDKCADCGA PEPDWASLNL GVLMCIECSG
VHRNLGVHIS KVRSLTLDVK VWEPSVLNLF QSIGNIYANS IWEELLHSGT SFTGDEMSKG
FSRSLSDRQK LFHMRKPNYD DSISVKEHFI HAKYAEKIFT HKIKDDQNLL SVAQQVWESV
HANDKKEVYR QIVRSGVDVN AIHGQASFSD SMDKPLASYV KPLHKNEDQV IEDFTDGCSL
LHLACLTADL GMVELLLQYG ANIHASNSKG QTPLHQCIIN RRPSIAKLLL TRGADPQAVD
GGGNTAIQLL SESSIDDSEL VILLAK
//
