ID   A0A2C9W574_MANES        Unreviewed;       661 AA.
AC   A0A2C9W574;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   22-FEB-2023, entry version 16.
DE   RecName: Full=CCHC-type domain-containing protein {ECO:0000259|PROSITE:PS50158};
DE   Flags: Fragment;
GN   ORFNames=MANES_03G066000 {ECO:0000313|EMBL:OAY54325.1};
OS   Manihot esculenta (Cassava) (Jatropha manihot).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Manihoteae;
OC   Manihot.
OX   NCBI_TaxID=3983 {ECO:0000313|EMBL:OAY54325.1, ECO:0000313|Proteomes:UP000091857};
RN   [1] {ECO:0000313|EMBL:OAY54325.1, ECO:0000313|Proteomes:UP000091857}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. AM560-2 {ECO:0000313|Proteomes:UP000091857};
RC   TISSUE=Leaf {ECO:0000313|EMBL:OAY54325.1};
RA   Bredeson J.V., Prochnik S.E., Lyons J.B., Schmutz J., Grimwood J.,
RA   Vrebalov J., Bart R.S., Amuge T., Ferguson M.E., Green R., Putnam N.,
RA   Stites J., Rounsley S., Rokhsar D.S.;
RT   "WGS assembly of Manihot esculenta.";
RL   Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CM004389; OAY54325.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2C9W574; -.
DR   EnsemblPlants; OAY54325; OAY54325; MANES_03G066000.
DR   Gramene; OAY54325; OAY54325; MANES_03G066000.
DR   Proteomes; UP000091857; Chromosome lg3.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd00303; retropepsin_like; 1.
DR   Gene3D; 2.40.70.10; Acid Proteases; 1.
DR   Gene3D; 4.10.60.10; Zinc finger, CCHC-type; 1.
DR   InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR   InterPro; IPR018061; Retropepsins.
DR   InterPro; IPR001878; Znf_CCHC.
DR   InterPro; IPR036875; Znf_CCHC_sf.
DR   PANTHER; PTHR33054; CCHC-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR33054:SF9; CCHC-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00077; RVP; 1.
DR   Pfam; PF00098; zf-CCHC; 1.
DR   SMART; SM00343; ZnF_C2HC; 1.
DR   SUPFAM; SSF50630; Acid proteases; 1.
DR   SUPFAM; SSF57756; Retrovirus zinc finger-like domains; 1.
DR   PROSITE; PS50158; ZF_CCHC; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00047};
KW   Reference proteome {ECO:0000313|Proteomes:UP000091857};
KW   Zinc {ECO:0000256|PROSITE-ProRule:PRU00047};
KW   Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00047}.
FT   DOMAIN          190..204
FT                   /note="CCHC-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50158"
FT   REGION          132..182
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          357..391
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        132..146
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        157..182
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         661
FT                   /evidence="ECO:0000313|EMBL:OAY54325.1"
SQ   SEQUENCE   661 AA;  76900 MW;  6C489BDDBA4C3B32 CRC64;
     MFTDRAQEQL INLRCPDLSH FKWYRDTFFS LVFTREDSQN HVWKEKFLAG LPALFAERVR
     DQIRSKHNGN IPYHDYTYGE LASKVVTTGI HLCNELKIHK QMQKERFYGK QILGNFCEQY
     GLPPIKFPST KFKGGRREAE NVRQHRRKHF FANKRPYKEQ HRRFSKPESS RKSKERKKPN
     PGKAEKTIVC YKCGKVGHYA NKCRVKQQIQ ALTIEEDLKE ALAKILLNET DSEQETLEIN
     AVDYTTEEEE SSTEEEEDQK EDCEGNCDYY KSLCAMNGLL VLTKEDNLIL DLIDNIEDPE
     KKREKLETYI GLYKDKETNT TAQDLTDKKI ESRQPSYDLK DILERVKNSK RQKEPTVAEL
     RSELNSVKTE IKEMKERINI LELLNEQQQQ LAMEEPEEDQ GGKDLNNLHY INMADRVITH
     KWHTRVTIVV HKNYVFETNA LIDSGADLNC INEGLVPSKY FSKTLEELHT ADGSKMSVKY
     KLNNTVICNQ GTCFEIPFLM VKGLSHPVIL GNPFLHMLYP IQITKEGIST EINGKVITFY
     FSSQPRLKEI DVLKNTVENK TKFVNSLKQE VIYKGIDDRL KEPKIQQRIK IIQEELLSSI
     CAESPDAFWT RKRHVVTLPY DPEFSEKAIP TKARPIAMGP RHLELCKKEI AELEAKGLIR
     K
//