ID A0A2C9W7L5_MANES Unreviewed; 257 AA.
AC A0A2C9W7L5;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Cyclin-dependent kinase inhibitor domain-containing protein {ECO:0000259|Pfam:PF02234};
GN ORFNames=MANES_03G148700 {ECO:0000313|EMBL:OAY55370.1};
OS Manihot esculenta (Cassava) (Jatropha manihot).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Manihoteae;
OC Manihot.
OX NCBI_TaxID=3983 {ECO:0000313|EMBL:OAY55370.1, ECO:0000313|Proteomes:UP000091857};
RN [1] {ECO:0000313|EMBL:OAY55370.1, ECO:0000313|Proteomes:UP000091857}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AM560-2 {ECO:0000313|Proteomes:UP000091857};
RC TISSUE=Leaf {ECO:0000313|EMBL:OAY55370.1};
RA Bredeson J.V., Prochnik S.E., Lyons J.B., Schmutz J., Grimwood J.,
RA Vrebalov J., Bart R.S., Amuge T., Ferguson M.E., Green R., Putnam N.,
RA Stites J., Rounsley S., Rokhsar D.S.;
RT "WGS assembly of Manihot esculenta.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleoplasm
CC {ECO:0000256|ARBA:ARBA00004642}.
CC -!- SIMILARITY: Belongs to the CDI family. ICK/KRP subfamily.
CC {ECO:0000256|ARBA:ARBA00010274}.
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DR EMBL; CM004389; OAY55370.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2C9W7L5; -.
DR STRING; 3983.A0A2C9W7L5; -.
DR EnsemblPlants; OAY55370; OAY55370; MANES_03G148700.
DR Gramene; OAY55370; OAY55370; MANES_03G148700.
DR OMA; RMETSIC; -.
DR Proteomes; UP000091857; Chromosome lg3.
DR GO; GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0004861; F:cyclin-dependent protein serine/threonine kinase inhibitor activity; IEA:InterPro.
DR GO; GO:0051726; P:regulation of cell cycle; IEA:InterPro.
DR Gene3D; 4.10.365.10; p27; 1.
DR InterPro; IPR003175; CDI_dom.
DR InterPro; IPR044898; CDI_dom_sf.
DR InterPro; IPR044275; KRP.
DR PANTHER; PTHR46776:SF3; CYCLIN-DEPENDENT KINASE INHIBITOR 4; 1.
DR PANTHER; PTHR46776; CYCLIN-DEPENDENT KINASE INHIBITOR 4-RELATED; 1.
DR Pfam; PF02234; CDI; 1.
DR PIRSF; PIRSF017811; CDK_inhib_pln; 2.
PE 3: Inferred from homology;
KW Protein kinase inhibitor {ECO:0000256|ARBA:ARBA00023013};
KW Reference proteome {ECO:0000313|Proteomes:UP000091857}.
FT DOMAIN 209..255
FT /note="Cyclin-dependent kinase inhibitor"
FT /evidence="ECO:0000259|Pfam:PF02234"
FT REGION 32..214
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 235..257
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 39..58
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 67..84
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 85..104
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 116..136
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 159..173
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 183..201
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 257 AA; 28934 MW; 56777A5D038441D3 CRC64;
MGKYMRKAKT TGEVAVMDLS LGVRTRAKTL ALQRQARLPA SPPQPSTASA QPASSGYLQL
RSRRLLKPPI LVHDSKRQKH THNKEVQNPN SNSMAASRVR VGSKDSRTNA AGLKKDVNGE
SKEEEIEEKH NDGDNNNNND SDIYESKDLG IEASFGENVL DIEGRERSTR ESTPCSFIRD
PETIRTPGST TRPASSTETS RRSRNSTRRH IPTAHEMDEF FAGAEEEQQR QFIEKYNFDP
INDKPLPGRY EWEKLDP
//
