ID A0A2C9WF90_MANES Unreviewed; 1104 AA.
AC A0A2C9WF90;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=FYVE-type domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=MANES_02G140700 {ECO:0000313|EMBL:OAY57988.1};
OS Manihot esculenta (Cassava) (Jatropha manihot).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Manihoteae;
OC Manihot.
OX NCBI_TaxID=3983 {ECO:0000313|EMBL:OAY57988.1, ECO:0000313|Proteomes:UP000091857};
RN [1] {ECO:0000313|EMBL:OAY57988.1, ECO:0000313|Proteomes:UP000091857}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AM560-2 {ECO:0000313|Proteomes:UP000091857};
RC TISSUE=Leaf {ECO:0000313|EMBL:OAY57988.1};
RA Bredeson J.V., Prochnik S.E., Lyons J.B., Schmutz J., Grimwood J.,
RA Vrebalov J., Bart R.S., Amuge T., Ferguson M.E., Green R., Putnam N.,
RA Stites J., Rounsley S., Rokhsar D.S.;
RT "WGS assembly of Manihot esculenta.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CM004388; OAY57988.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2C9WF90; -.
DR STRING; 3983.A0A2C9WF90; -.
DR EnsemblPlants; OAY57988; OAY57988; MANES_02G140700.
DR Gramene; OAY57988; OAY57988; MANES_02G140700.
DR OMA; HPRGIPM; -.
DR OrthoDB; 551430at2759; -.
DR Proteomes; UP000091857; Chromosome lg2.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd00065; FYVE_like_SF; 1.
DR CDD; cd13365; PH_PLC_plant-like; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 2.130.10.30; Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II; 2.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR013591; Brevis_radix_dom.
DR InterPro; IPR027988; BRX_N.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR009091; RCC1/BLIP-II.
DR InterPro; IPR000408; Reg_chr_condens.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR22870; REGULATOR OF CHROMOSOME CONDENSATION; 1.
DR PANTHER; PTHR22870:SF437; X-LINKED RETINITIS PIGMENTOSA GTPASE REGULATOR-RELATED; 1.
DR Pfam; PF08381; BRX; 1.
DR Pfam; PF16627; BRX_assoc; 1.
DR Pfam; PF13713; BRX_N; 1.
DR Pfam; PF01363; FYVE; 1.
DR Pfam; PF16457; PH_12; 1.
DR Pfam; PF00415; RCC1; 6.
DR PRINTS; PR00633; RCCNDNSATION.
DR SMART; SM00064; FYVE; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF50985; RCC1/BLIP-II; 1.
DR PROSITE; PS51514; BRX; 1.
DR PROSITE; PS00626; RCC1_2; 3.
DR PROSITE; PS50012; RCC1_3; 7.
DR PROSITE; PS50178; ZF_FYVE; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000091857};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT REPEAT 267..328
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 329..380
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 381..435
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 436..487
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 500..551
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 552..603
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 604..655
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT DOMAIN 660..722
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT DOMAIN 1031..1086
FT /note="BRX"
FT /evidence="ECO:0000259|PROSITE:PS51514"
FT REGION 135..174
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 728..754
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 766..800
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 833..860
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1007..1030
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 865..941
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 143..170
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1007..1022
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1104 AA; 119512 MW; 38365D96EEFDB36F CRC64;
MSRTDRMASD LSRTGPVERD IEQAITALKK GAYLLKYGRR GKPKVCPFRL SNDESVLIWF
SGKEEKHLRL SHVSRIISGQ RTPIFQRYPR PEKEYQSFSL IYNDRSLDLI CKDKDEAEVW
FSGLKSLISR SHHRKWRTES RSDGVPSEAN SPRTYTRRSS PLNSPFGSND SLQKDRDHLR
LHSPYESPPK NGLDKALSEV TLYAVPPKGF FPSDSASGSV HSLSSGGSDS VHGHMKAMAM
DAFRVSLSSA VSSSSQGSGH DDGDALGDVF IWGEGTGDGV LGGGNHRVGS GFAGKMDSLL
PKALESTVVL DVQNIACGGR HAALVTRQGE IFSWGEESGG RLGHGVDSDV LHPKLIDALS
NINIELVACG EYHTCAVTLS GDLYTWGDGT YNFGLLGHGN EVSHWVPKRV NGPLEGIHVS
SISCGPWHTA VVTSAGQLFT FGDGTFGVLG HGDRKSVSLP KEVESLKGLR TLQAACGVWH
TAAVVEVMVG NSSSSNSSSG KLFTWGDGDK GRLGHGDKEA KLVPTCVAAL VEPNFCQVAC
GHSLTVALTT SGHVYTMGSP VYGQLGNPHA DGKLPNRVEG KLSKSFVQEI ACGAYHVAVL
TSKTEVYTWG KGANGRLGHG DTDDRNIPSL VEALRDKQVK NIACGTNFTA AICLHKWVSG
VDQSMCSGCH LPFNFKRKRH NCYNCGLVFC HSCSIKKSLK ASMAPNPNKP YRVCDNCFNK
LKKTIETDAS SQSSVSRRGG VNHGSNGFID KDEKLDSTSG AQLARFSSME SLKQAESRSK
RNKKLEFNSS RVSPVPNGGS NWGALNISKS FNPVFGSSKK FFSASVPGSR IVSRATSPIS
RRPSPPRSTT PTPTLGGLTS PKLVVDDARR TNESLSQEVI KLRAQVENLT RKAQLQEVEL
ERTTKQLKEA IAIAGEETAK CKAAKEVIKS LTAQLKDMAE RLPVGAARNM KSPSFTSLAS
TPSNDIPNVS LDCLNGQIAS EGPETNRLNS QLSNGSGVIG IRNSGYSKQG HFDANGRNGS
RTKEGASQHE AEWVEQDEPG VYITLTSLPG GVKDLKRVRF SRKRFSEKQA EQWWAENRAR
VYEQYNVRMV DKSSVGVGSD DLAH
//
