ID A0A2D0AN18_9SPHN Unreviewed; 612 AA.
AC A0A2D0AN18;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=X-Pro aminopeptidase {ECO:0000313|EMBL:OWQ94436.1};
GN ORFNames=CDQ91_15820 {ECO:0000313|EMBL:OWQ94436.1};
OS Sphingopyxis witflariensis.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingopyxis.
OX NCBI_TaxID=173675 {ECO:0000313|EMBL:OWQ94436.1, ECO:0000313|Proteomes:UP000197097};
RN [1] {ECO:0000313|EMBL:OWQ94436.1, ECO:0000313|Proteomes:UP000197097}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14551 {ECO:0000313|EMBL:OWQ94436.1,
RC ECO:0000313|Proteomes:UP000197097};
RX PubMed=12508864; DOI=10.1099/ijs.0.02217-0;
RA Kampfer P., Witzenberger R., Denner E.B., Busse H.J., Neef A.;
RT "Sphingopyxis witflariensis sp. nov., isolated from activated sludge.";
RL Int. J. Syst. Evol. Microbiol. 52:2029-2034(2002).
CC -!- SIMILARITY: Belongs to the peptidase M24B family.
CC {ECO:0000256|ARBA:ARBA00008766}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWQ94436.1}.
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DR EMBL; NISJ01000009; OWQ94436.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2D0AN18; -.
DR OrthoDB; 9806388at2; -.
DR Proteomes; UP000197097; Unassembled WGS sequence.
DR GO; GO:0070006; F:metalloaminopeptidase activity; IEA:InterPro.
DR CDD; cd01085; APP; 1.
DR Gene3D; 3.90.230.10; Creatinase/methionine aminopeptidase superfamily; 1.
DR Gene3D; 3.40.350.10; Creatinase/prolidase N-terminal domain; 2.
DR InterPro; IPR029149; Creatin/AminoP/Spt16_NTD.
DR InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR InterPro; IPR000587; Creatinase_N.
DR InterPro; IPR000994; Pept_M24.
DR InterPro; IPR033740; Pept_M24B.
DR InterPro; IPR032416; Peptidase_M24_C.
DR PANTHER; PTHR43763; XAA-PRO AMINOPEPTIDASE 1; 1.
DR PANTHER; PTHR43763:SF6; XAA-PRO AMINOPEPTIDASE 1; 1.
DR Pfam; PF01321; Creatinase_N; 1.
DR Pfam; PF16189; Creatinase_N_2; 1.
DR Pfam; PF00557; Peptidase_M24; 1.
DR Pfam; PF16188; Peptidase_M24_C; 1.
DR SUPFAM; SSF55920; Creatinase/aminopeptidase; 1.
DR SUPFAM; SSF53092; Creatinase/prolidase N-terminal domain; 1.
PE 3: Inferred from homology;
KW Aminopeptidase {ECO:0000313|EMBL:OWQ94436.1};
KW Hydrolase {ECO:0000313|EMBL:OWQ94436.1};
KW Protease {ECO:0000313|EMBL:OWQ94436.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000197097}.
FT DOMAIN 13..144
FT /note="Creatinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01321"
FT DOMAIN 316..532
FT /note="Peptidase M24"
FT /evidence="ECO:0000259|Pfam:PF00557"
FT DOMAIN 544..603
FT /note="Peptidase M24 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16188"
SQ SEQUENCE 612 AA; 64820 MW; 310704F9CC89FBCD CRC64;
MSTPRSSAVH AERLARLRAE LKALGLDGFV VPISDEHMSE YVGEYAQRMA WLTGFGGSAG
TAAVLPEKAA VFIDGRYTVQ VRDQVDGSLF DYVGVPQSSV AEWLGTNVGA GQKIGFDPWL
HGIDWARGLG HALKAKGAQL VAVDANPLDA AWDDQPAPSD APVAVHDARL AGQSAVDKRA
GIADWLRAKG LDTTVMTALD SLAWTFNIRG SDVSHTPVGL AFALLHADAT ADLFIAPEKI
TDAVRAHLGN SVRIHDRSAF EAALAGLKDK KVAVDPDRAV AAIFTALEAA GAKIERHRDP
AVLPKAIKND VELNGTRAAH VRDGVAVSRF LQWMEKVAPQ GGLNELGAAA KLREFREEGG
GLVDLSFDTI SAAGPNGALP HYKVDETTNR AIETGTLYLV DSGGQYADGT TDITRTIAIG
APTAEMRRRF TQVLKGHIAL AMARFPKGTR GSQLDILARQ YLWADGVDYA HGTGHGVGAY
LAVHEGPQRI AKPAGGQAGT EEALHAGMIL SNEPGYYKAG AFGIRIENLV IVVPMKIDGA
EEDMLGFETI TFAPIAQNLI EGALLSPAEA DWLDAYHAQV LEKLGPGMEG ADRDWLTAAC
APVDRAPAAL AA
//
