ID   A0A2D0HDJ8_9NOSO        Unreviewed;       876 AA.
AC   A0A2D0HDJ8;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   SubName: Full=Trans-splicing intein-formed DNA polymerase III subunit alpha N-terminal partner DnaE-N {ECO:0000313|EMBL:PHM07530.1};
GN   ORFNames=CK516_26520 {ECO:0000313|EMBL:PHM07530.1};
OS   Nostoc sp. 'Peltigera malacea cyanobiont' DB3992.
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae; Nostoc.
OX   NCBI_TaxID=1206980 {ECO:0000313|EMBL:PHM07530.1, ECO:0000313|Proteomes:UP000223928};
RN   [1] {ECO:0000313|EMBL:PHM07530.1, ECO:0000313|Proteomes:UP000223928}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DB3992 {ECO:0000313|EMBL:PHM07530.1};
RA   Gagunashvili A.N., Andresson O.S.;
RT   "Distinctive characters of Nostoc genomes in cyanolichens.";
RL   Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PHM07530.1}.
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DR   EMBL; NSHF01000311; PHM07530.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2D0HDJ8; -.
DR   Proteomes; UP000223928; Unassembled WGS sequence.
DR   GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0016539; P:intein-mediated protein splicing; IEA:InterPro.
DR   CDD; cd00081; Hint; 1.
DR   CDD; cd12113; PHP_PolIIIA_DnaE3; 1.
DR   Gene3D; 1.10.10.1600; Bacterial DNA polymerase III alpha subunit, thumb domain; 1.
DR   Gene3D; 2.170.16.10; Hedgehog/Intein (Hint) domain; 1.
DR   Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR   InterPro; IPR011708; DNA_pol3_alpha_NTPase_dom.
DR   InterPro; IPR041931; DNA_pol3_alpha_thumb_dom.
DR   InterPro; IPR040982; DNA_pol3_finger.
DR   InterPro; IPR004805; DnaE2/DnaE/PolC.
DR   InterPro; IPR003587; Hint_dom_N.
DR   InterPro; IPR036844; Hint_dom_sf.
DR   InterPro; IPR006141; Intein_N.
DR   InterPro; IPR004013; PHP_dom.
DR   InterPro; IPR003141; Pol/His_phosphatase_N.
DR   InterPro; IPR016195; Pol/histidinol_Pase-like.
DR   NCBIfam; TIGR01445; intein_Nterm; 1.
DR   NCBIfam; TIGR00594; polc; 1.
DR   PANTHER; PTHR32294; DNA POLYMERASE III SUBUNIT ALPHA; 1.
DR   PANTHER; PTHR32294:SF0; DNA POLYMERASE III SUBUNIT ALPHA; 1.
DR   Pfam; PF07733; DNA_pol3_alpha; 1.
DR   Pfam; PF17657; DNA_pol3_finger; 1.
DR   Pfam; PF02811; PHP; 1.
DR   SMART; SM00306; HintN; 1.
DR   SMART; SM00481; POLIIIAc; 1.
DR   SUPFAM; SSF51294; Hedgehog/intein (Hint) domain; 1.
DR   SUPFAM; SSF89550; PHP domain-like; 1.
DR   PROSITE; PS50817; INTEIN_N_TER; 1.
PE   4: Predicted;
KW   DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW   DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022932};
KW   Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW   Reference proteome {ECO:0000313|Proteomes:UP000223928};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          4..71
FT                   /note="Polymerase/histidinol phosphatase N-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00481"
FT   DOMAIN          773..871
FT                   /note="Hint"
FT                   /evidence="ECO:0000259|SMART:SM00306"
SQ   SEQUENCE   876 AA;  99714 MW;  1EAA47E69F76B4DB CRC64;
     MSFVPLHIHS DYSLLDGASQ LPELVDRAIA LGMKAIALTD HGVMYGAVEL IKICRSQNIK
     PIIGNEMYII NGDIEKQERR PKYHQVVLAK NTKGYKNLVK LTTISHLKGV QGKGIFSRPC
     INKDLLKQYH EGLIVTSACL GGEIPQAILS NRPDAARKVA QWYKDVFGDD YYLEIQDHGS
     QEDRIVNVEI VKIARELGIK IVATNDSHFI SCFDVEAHDA LLCIQTGKLI AEDKRMRYSG
     TEYLKSGEEM QQLFRDHLPD DVIVEAIATT EEVADKVEPY HIMGEPQIPT PPIPSGHTAD
     TYAEDVAWSG LLDRLNRKSR QEVDSVYKER LEYELKMIQQ MGFSKYFLVV WDYIKFARDN
     NIPVGPGRGS AAGSLVAYAM RITNIDPVHH GLLFERFLNP ERKSMPDIDT DFCIEQRDKV
     IEYVTEKYGA DRVAQIITFN RLTSKAVLKD VARVLNIPYG EADKMAKMIP VVRGKPTKLK
     VMVSDKTPEP EFKEKYDKEP HVRHWLDMAM RIEGTNKTFG VHAAGVVISA DPLDEIVPLQ
     KNNDGSVITQ YFMEDLESMG LLKMDFLGLR NLTLIQKTVD LIQETRGYRV DPDEIPRQER
     KAQRILAKGE HSSLPKDVQK TYELLEAGEL EGIFQLESSG MRQIVRDLKP SNIEDISSIL
     ALYRPGPLDA GLIPKFINRK HGREKIDYQH QILEPILDET YGIMVYQEQI MKIAQDMAGY
     TLGQADLLRR AMGKKKVSEM QKQREKFVDG AAKNGVQKKV ADELFEQMLK FAEYCLSYDT
     EILTVEYGLM PIGEIVEKRI ECTVYSVDNN GNIYTQPVAQ WHDRGEQEVF EYCLEDGSLI
     RATKDHKFMT ADGQMLPIDE IFERELDLMR VENLPN
//