ID A0A2D0HM31_9NOSO Unreviewed; 1801 AA.
AC A0A2D0HM31;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=CK516_09120 {ECO:0000313|EMBL:PHM10343.1};
OS Nostoc sp. 'Peltigera malacea cyanobiont' DB3992.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae; Nostoc.
OX NCBI_TaxID=1206980 {ECO:0000313|EMBL:PHM10343.1, ECO:0000313|Proteomes:UP000223928};
RN [1] {ECO:0000313|EMBL:PHM10343.1, ECO:0000313|Proteomes:UP000223928}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DB3992 {ECO:0000313|EMBL:PHM10343.1};
RA Gagunashvili A.N., Andresson O.S.;
RT "Distinctive characters of Nostoc genomes in cyanolichens.";
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001433};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC EC=2.7.11.1; Evidence={ECO:0000256|ARBA:ARBA00000775};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PHM10343.1}.
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DR EMBL; NSHF01000059; PHM10343.1; -; Genomic_DNA.
DR Proteomes; UP000223928; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd14014; STKc_PknB_like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR43642; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G; 1.
DR PANTHER; PTHR43642:SF1; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF00069; Pkinase; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Kinase {ECO:0000313|EMBL:PHM10343.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000223928};
KW Serine/threonine-protein kinase {ECO:0000313|EMBL:PHM10343.1};
KW Transferase {ECO:0000313|EMBL:PHM10343.1}.
FT DOMAIN 11..274
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 1557..1801
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 1507..1545
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1801 AA; 202527 MW; 1946E2FD960F9BBF CRC64;
MISSVVTIPG YQVSEELYNG SRTLVYRAVR ESDQQPVVIK LLKNPYPSFS ELVQFRNQYT
IAKNLNSPSI VQTYSLEPYQ NGYALVMQDF GGISLKTEMG AKQHSLREFL PLAISLCKTL
DILIRSRIIH KDIKPANILI NPETKQVKLI DFSIASLLPR ETQTLISPNV LEGTLAYISP
EQTGRMNRGI DYRTDFYSLG VTFYELLTGE LPFQSEDAME LVHCHIAKVP PFLHQINPEI
PFVLAEIIKK LMAKNAEERY QSALGLKYDL EKCLVQLKET GKIETFPIAQ RDVCDRFIIP
DKLYGREAEI ETLLNAFERV SKGTTEMMLV AGFSGIGKTA VVNEVHKPIV GKRGYFIKGK
YDQFNRNIPL SAFVQAFRDL MGQLLSETDT HLQQWQDKII TALGENAQVI IEVIPELKRI
IGSQPLATEL SGMAAQNRFN LLFQKFIQVF TTQEHPLVMF LDDLQWADSA SLKLMQLLMD
ESQKGYLLLL GAYRDNEVFP AHPLMLRLDE IGNAGAKINK ITLSPLCQVS VNKLLADTLH
CQPEVAQPLM QLVYQKTKGN PFFTTQFLKA LHKDNYIQFN SQIGHWQCDI AQVKQLVLTD
DVVEFMTQRL QKLTPATQYV LKLAACIGNQ FDLHILAIVY QQSQTETAAA LWEALEFGLI
LPTSEVYKFY AGYENQATNQ EIAHSVTYKF LHDRVQQAAY SLIHEDHKQT THVKIGRLLW
QNTPEAELEN QIFAIANQLN IGLEHFHQPT ERHELAQLNL MAGKKAKAST AYSSAIAYLK
TGIQLLPFNP WESDYNLTLS LYSEATETSF LCGEIEAMED FAQEILQHAK AIADTAKVYE
VKIEAYIAQG KFLLAIDTAM QFLQSLGIEF PQEPTASDFV LALQETEASL SGKTVAELVD
LPEMQNPELR AALRVLVKVT TPAYMAKPEL HRLVVLKKVA LSVKYGNTSA SAFAYSGYGL
MLCGQPGSIS TGYEFGKLAL QLLSKFQDRE HEARVLVVVH LCIAHWKEPV TAMLQPLLQA
YTSGLDSGDL IYASYAAHLY CFQAYIAGQE LTKLADELAI YGAAIEKINQ KHTLNYNNIY
YQVVLNLIES KTTPWELVGT AYDERSMLTL HEQSNDGAAL WHFFVNKLML SYLFQALDLA
VEYAAKAKQY SGSGYATVNL PILNFYDSLL QLALFPTSPP EEQERILQQV AENQDTMQQW
ANYAPMNHLH RFQLVEAEKY RILAQKTAAM EFYDLAIAGA KENGYIQEAA LSNELAAKFY
LDWGREKVAQ AYIEQAYYSY ARWGAKAKLE NLERRYPELL RVIVQQKNLK LNSQETLCNT
VISSASNHSS TQISSSSSSV NLVLDFGSVF KASQAISTAI HLDQLIQTLT QIILENAGAD
RCALILFQDG SWQVRAIATL EGIMLQTAPL NNHPSVPVKL IQYVKNTLET VVIDDLKTHL
PSVIGEYMRQ YQPKSALCMP IRNQGHLLGI LYLENQLTMG AFVGDRLDVL QLLTTQAAIS
LENALLYNTL EQKVEQRTQE LHSKNQQLSH TLQELQQTQA QLIHAEKMSS LGQMVAGIAH
EINNPVNFIS GNISHLKNYF QDLVSGIRLY QHQYPQPTTE IQTYFQEKDL DYAIKDIPNL
LDSVKQGSQR IQNIVLSLRN FARLDEADIK AVNIHEGIEN TLLILQHRLT KIAIIKNYAE
LPKVSCHAKQ INQVIINVLN NAIDALNEAK ITTPTITIRT ELSNSLTNSV SIYIVDNGTG
ISDEMQKRVF DPFFTTKTIG KGTGLGLTIA YSIMSTHGGQ INVFSKLGQG TEFEIILPVQ
G
//
