ID A0A2D0KBA4_9GAMM Unreviewed; 812 AA.
AC A0A2D0KBA4;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=DNA primase {ECO:0000313|EMBL:PHM60605.1};
GN ORFNames=Xsto_03834 {ECO:0000313|EMBL:PHM60605.1};
OS Xenorhabdus stockiae.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Xenorhabdus.
OX NCBI_TaxID=351614 {ECO:0000313|EMBL:PHM60605.1, ECO:0000313|Proteomes:UP000222366};
RN [1] {ECO:0000313|EMBL:PHM60605.1, ECO:0000313|Proteomes:UP000222366}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17904 {ECO:0000313|EMBL:PHM60605.1,
RC ECO:0000313|Proteomes:UP000222366};
RX PubMed=28993611; DOI=10.1038/s41564-017-0039-9;
RA Tobias N.J., Wolff H., Djahanschiri B., Grundmann F., Kronenwerth M.,
RA Shi Y.M., Simonyi S., Grun P., Shapiro-Ilan D., Pidot S.J., Stinear T.P.,
RA Ebersberger I., Bode H.B.;
RT "Natural product diversity associated with the nematode symbionts
RT Photorhabdus and Xenorhabdus.";
RL Nat. Microbiol. 2:1676-1685(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PHM60605.1}.
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DR EMBL; NJAJ01000058; PHM60605.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2D0KBA4; -.
DR Proteomes; UP000222366; Unassembled WGS sequence.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:1990077; C:primosome complex; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003896; F:DNA primase activity; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd01029; TOPRIM_primases; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR Gene3D; 3.90.580.10; Zinc finger, CHC2-type domain; 1.
DR InterPro; IPR004968; DNA_primase/NTPase_C.
DR InterPro; IPR036977; DNA_primase_Znf_CHC2.
DR InterPro; IPR014015; Helicase_SF3_DNA-vir.
DR InterPro; IPR045455; NrS-1_pol-like_helicase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014818; Phage/plasmid_primase_P4_C.
DR InterPro; IPR013237; Phage_T7_Gp4_N.
DR InterPro; IPR034154; TOPRIM_DnaG/twinkle.
DR InterPro; IPR006171; TOPRIM_domain.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR35372; ATP BINDING PROTEIN-RELATED; 1.
DR PANTHER; PTHR35372:SF2; SF3 HELICASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF08706; D5_N; 1.
DR Pfam; PF19263; DUF5906; 1.
DR Pfam; PF03288; Pox_D5; 1.
DR Pfam; PF08273; Prim_Zn_Ribbon; 1.
DR Pfam; PF13362; Toprim_3; 1.
DR SMART; SM00885; D5_N; 1.
DR SMART; SM00778; Prim_Zn_Ribbon; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR SUPFAM; SSF57783; Zinc beta-ribbon; 1.
DR PROSITE; PS51206; SF3_HELICASE_1; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Primosome {ECO:0000256|ARBA:ARBA00022515};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 507..660
FT /note="SF3 helicase"
FT /evidence="ECO:0000259|PROSITE:PS51206"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 812 AA; 89874 MW; D161445D4D342822 CRC64;
MADIQHTQTH PKFTSSDHTS SQNPRDLIQT VKKSAMYHWE NLLSACGIDI PAKGKHGACP
VCGGTDRFHF IDDHHHGNWH CRQCDTPNYG DGLDLVARTK GISITEAAKI IAGVLALPLP
EPKPARETIQ TTQSIAEKVV SLMAQTVAGQ SPYLAAKGLD FPNQRLLLNN STLLALTTLD
KKVTGAQIIE PNGEKKLLSG SQKKGAFIAL SELEDNHDTV IITEGYATAL TVSQLYKGTV
LAALDAGNLY SVAKAVRERW SDTKIIIAAD NDWHHPDELD KNGKPKVNIG RISAEKAALA
VNGWISLPPT EYKADWDDYR QQYGVERAKL TFAQGLYQPA RTKKKAAAQP NDTESSKLTL
CQMGASQRGE VLLARYDSDL ALDGASETVH HYDGIVWRPV SDRDLKREMV AAFMEEKLPY
SPHGISSAVD ALKLQLPMMQ PPERHLIGFS NGVFDLKACQ FRPHRKSDWL LLANDVAFNS
PVSGETLQDH ASQFWRWLNR ATANCENKFD RVLAALFMVL ANRYDWQFFL EITGAGGSGK
SILAEICSML AGKGNTVSAS MAALENPRER ALIVGYSLII LPDQTRYVGD GSGIKAITGG
DEVAIDPKHK QPYSTRIPAV VLAVNNNAMS FSDRSGGVSR RRVIFNFSEV VPENERDPLL
RDKIAAELPV IIRHLLHRFA DPQAARRLLA EQQKSEEALD IKRGTDPLVD FCGYLVASHE
TDGLLIGNAE IVPFNPRKYL YHAYLAYMKG NNLNKPVSVT RFGMDMPGAL AEYGQYYLRK
KSKYGIRSNL NLNIDTAIEW MPKLIRDNLP EE
//
