ID A0A2D0KM97_9GAMM Unreviewed; 255 AA.
AC A0A2D0KM97;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE RecName: Full=Sulfate transporter CysZ {ECO:0000256|HAMAP-Rule:MF_00468};
GN Name=cysZ {ECO:0000256|HAMAP-Rule:MF_00468};
GN ORFNames=Xsto_02838 {ECO:0000313|EMBL:PHM64564.1};
OS Xenorhabdus stockiae.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Xenorhabdus.
OX NCBI_TaxID=351614 {ECO:0000313|EMBL:PHM64564.1, ECO:0000313|Proteomes:UP000222366};
RN [1] {ECO:0000313|EMBL:PHM64564.1, ECO:0000313|Proteomes:UP000222366}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17904 {ECO:0000313|EMBL:PHM64564.1,
RC ECO:0000313|Proteomes:UP000222366};
RX PubMed=28993611; DOI=10.1038/s41564-017-0039-9;
RA Tobias N.J., Wolff H., Djahanschiri B., Grundmann F., Kronenwerth M.,
RA Shi Y.M., Simonyi S., Grun P., Shapiro-Ilan D., Pidot S.J., Stinear T.P.,
RA Ebersberger I., Bode H.B.;
RT "Natural product diversity associated with the nematode symbionts
RT Photorhabdus and Xenorhabdus.";
RL Nat. Microbiol. 2:1676-1685(2017).
CC -!- FUNCTION: High affinity, high specificity proton-dependent sulfate
CC transporter, which mediates sulfate uptake. Provides the sulfur source
CC for the cysteine synthesis pathway. {ECO:0000256|HAMAP-Rule:MF_00468}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000256|HAMAP-
CC Rule:MF_00468}; Multi-pass membrane protein {ECO:0000256|HAMAP-
CC Rule:MF_00468}.
CC -!- SIMILARITY: Belongs to the CysZ family. {ECO:0000256|HAMAP-
CC Rule:MF_00468}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PHM64564.1}.
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DR EMBL; NJAJ01000027; PHM64564.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2D0KM97; -.
DR Proteomes; UP000222366; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015116; F:sulfate transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0019344; P:cysteine biosynthetic process; IEA:UniProtKB-UniRule.
DR GO; GO:0000103; P:sulfate assimilation; IEA:InterPro.
DR HAMAP; MF_00468; CysZ; 1.
DR InterPro; IPR022985; Sulfate_CysZ.
DR PANTHER; PTHR37468; SULFATE TRANSPORTER CYSZ; 1.
DR PANTHER; PTHR37468:SF1; SULFATE TRANSPORTER CYSZ; 1.
DR Pfam; PF07264; EI24; 1.
PE 3: Inferred from homology;
KW Amino-acid biosynthesis {ECO:0000256|HAMAP-Rule:MF_00468};
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519, ECO:0000256|HAMAP-
KW Rule:MF_00468};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475, ECO:0000256|HAMAP-
KW Rule:MF_00468}; Cysteine biosynthesis {ECO:0000256|HAMAP-Rule:MF_00468};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|HAMAP-Rule:MF_00468};
KW Sulfate transport {ECO:0000256|ARBA:ARBA00023032, ECO:0000256|HAMAP-
KW Rule:MF_00468};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|HAMAP-
KW Rule:MF_00468};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|HAMAP-
KW Rule:MF_00468};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|HAMAP-Rule:MF_00468}.
FT TRANSMEM 32..52
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00468"
FT TRANSMEM 72..93
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00468"
FT TRANSMEM 144..164
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00468"
FT TRANSMEM 210..243
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00468"
SQ SEQUENCE 255 AA; 29430 MW; B565EDA6452F60D7 CRC64;
MTNSTKLPKH LGGFHYIVQG WHLVTRPGIK RFVLLPLLAN ILLIGGAFWW LYQKMDGWIQ
WVLDKVPDWM QWLSYLIWPL AVISVLLIFT YFFSTLANFI ASPFNGLLAE KLEAQLTGIP
APDTDIFDLL KDVPRILKRE IVKILYYLPR AIALLLLYFI PGIGQTIAPV LWFIFSAWML
AIQYCDYPFD NHKVSFIGMR NTLRQDKIDN LQFGATVSIL TMIPVINLFI MPVAVCGATA
MWVDRYRAQH AIRNR
//
