ID A0A2D0KRA8_9GAMM Unreviewed; 431 AA.
AC A0A2D0KRA8;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Hemolysin transport protein {ECO:0000313|EMBL:PHM65757.1};
GN ORFNames=Xsto_01702 {ECO:0000313|EMBL:PHM65757.1};
OS Xenorhabdus stockiae.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Xenorhabdus.
OX NCBI_TaxID=351614 {ECO:0000313|EMBL:PHM65757.1, ECO:0000313|Proteomes:UP000222366};
RN [1] {ECO:0000313|EMBL:PHM65757.1, ECO:0000313|Proteomes:UP000222366}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17904 {ECO:0000313|EMBL:PHM65757.1,
RC ECO:0000313|Proteomes:UP000222366};
RX PubMed=28993611; DOI=10.1038/s41564-017-0039-9;
RA Tobias N.J., Wolff H., Djahanschiri B., Grundmann F., Kronenwerth M.,
RA Shi Y.M., Simonyi S., Grun P., Shapiro-Ilan D., Pidot S.J., Stinear T.P.,
RA Ebersberger I., Bode H.B.;
RT "Natural product diversity associated with the nematode symbionts
RT Photorhabdus and Xenorhabdus.";
RL Nat. Microbiol. 2:1676-1685(2017).
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PHM65757.1}.
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DR EMBL; NJAJ01000013; PHM65757.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2D0KRA8; -.
DR Proteomes; UP000222366; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 2.40.50.100; -; 1.
DR InterPro; IPR043602; CusB_dom_1.
DR InterPro; IPR032317; HlyD_D23.
DR PANTHER; PTHR30386:SF27; EXPORTED PROTEIN-RELATED; 1.
DR PANTHER; PTHR30386; MEMBRANE FUSION SUBUNIT OF EMRAB-TOLC MULTIDRUG EFFLUX PUMP; 1.
DR Pfam; PF00529; CusB_dom_1; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR PRINTS; PR01490; RTXTOXIND.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022519};
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 26..50
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 158..383
FT /note="Cation efflux system protein CusB"
FT /evidence="ECO:0000259|Pfam:PF00529"
FT DOMAIN 234..335
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT COILED 118..152
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 234..261
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 431 AA; 49707 MW; 3E1F5DBE4326758B CRC64;
MTAMNKLFRQ EALDNKKSRW TGKAILIAKV PAWIICVASI VFLTILFLFI TFGNYARRIN
VYGEVITNPH PINILASQQG FILKSFVKVG DIVKKGQKIY QVDISQVTES GKTSTNAQNS
LKNQLTQINK IIENLEHNKS VTLASLEEQK NQYELSHEKD RIIVENARQG VEFAKENMKN
YKTYQERGLI TKDQFNNYGY SYYQQQNMYQ NLYSQYISDS LKITSLNSEI MLQKADFDKQ
ISQYKIQQDD LEQKLTEMNV SGSIFITSPI DGRIESLNFT DGQMVVTNDN LVQVSPDDVK
PTYYLILWVP NSSLPYIKKG DGINIRYDAF PFEKFGQFSG DINNISYIPA TAQEMSHYRS
SPVNVPGDKT ESYYKVLVGL KKEQFNYNGR KLYLSNGMKA QSTFFLEKRP LYQWMFSPFY
DMKKTLTGPQ K
//
