ID A0A2D0LHF6_9GAMM Unreviewed; 414 AA.
AC A0A2D0LHF6;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=Aromatic amino acid permease {ECO:0000256|RuleBase:RU367149};
GN ORFNames=Xkoz_00151 {ECO:0000313|EMBL:PHM75139.1};
OS Xenorhabdus kozodoii.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Xenorhabdus.
OX NCBI_TaxID=351676 {ECO:0000313|EMBL:PHM75139.1, ECO:0000313|Proteomes:UP000221101};
RN [1] {ECO:0000313|EMBL:PHM75139.1, ECO:0000313|Proteomes:UP000221101}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17907 {ECO:0000313|EMBL:PHM75139.1,
RC ECO:0000313|Proteomes:UP000221101};
RX PubMed=28993611; DOI=10.1038/s41564-017-0039-9;
RA Tobias N.J., Wolff H., Djahanschiri B., Grundmann F., Kronenwerth M.,
RA Shi Y.M., Simonyi S., Grun P., Shapiro-Ilan D., Pidot S.J., Stinear T.P.,
RA Ebersberger I., Bode H.B.;
RT "Natural product diversity associated with the nematode symbionts
RT Photorhabdus and Xenorhabdus.";
RL Nat. Microbiol. 2:1676-1685(2017).
CC -!- FUNCTION: Involved in transporting aromatic amino acids across the
CC cytoplasmic membrane. {ECO:0000256|RuleBase:RU367149}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429, ECO:0000256|RuleBase:RU367149}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004429,
CC ECO:0000256|RuleBase:RU367149}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the amino acid/polyamine transporter 2 family.
CC Mtr/TnaB/TyrP permease subfamily. {ECO:0000256|ARBA:ARBA00005452,
CC ECO:0000256|RuleBase:RU367149}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PHM75139.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; NJCX01000001; PHM75139.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2D0LHF6; -.
DR OrthoDB; 18749at2; -.
DR Proteomes; UP000221101; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015173; F:aromatic amino acid transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR018227; Amino_acid_transport_2.
DR InterPro; IPR013059; Trp_tyr_transpt.
DR NCBIfam; TIGR00837; araaP; 1.
DR PANTHER; PTHR46997; LOW AFFINITY TRYPTOPHAN PERMEASE-RELATED; 1.
DR PANTHER; PTHR46997:SF1; LOW AFFINITY TRYPTOPHAN PERMEASE-RELATED; 1.
DR Pfam; PF03222; Trp_Tyr_perm; 1.
DR PIRSF; PIRSF006060; AA_transporter; 2.
DR PRINTS; PR00166; AROAAPRMEASE.
PE 3: Inferred from homology;
KW Amino-acid transport {ECO:0000256|RuleBase:RU367149};
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519,
KW ECO:0000256|RuleBase:RU367149};
KW Cell membrane {ECO:0000256|RuleBase:RU367149};
KW Membrane {ECO:0000256|RuleBase:RU367149};
KW Transmembrane {ECO:0000256|RuleBase:RU367149};
KW Transmembrane helix {ECO:0000256|RuleBase:RU367149};
KW Transport {ECO:0000256|RuleBase:RU367149}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367149"
FT TRANSMEM 39..64
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367149"
FT TRANSMEM 85..108
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367149"
FT TRANSMEM 128..145
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367149"
FT TRANSMEM 152..170
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367149"
FT TRANSMEM 190..207
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367149"
FT TRANSMEM 228..247
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367149"
FT TRANSMEM 289..310
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367149"
FT TRANSMEM 322..340
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367149"
FT TRANSMEM 346..365
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367149"
FT TRANSMEM 386..407
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367149"
SQ SEQUENCE 414 AA; 45139 MW; 050B96EA08F082BE CRC64;
MTIEVTQNLK RPSIFGGAMI IAGTAVGAGM FSIPIVTSGV WFTGSIILLL YTCACMYFSG
LMILEANMNY PVGSSFHTVT KDLLGKGWCS LNDLSIAFVL YILTYAYVSA GSSIISHNIE
NIIPLPQSIS GLCFAFIVAF IVWLSTKAVD RLSTILIGGM VITFIMSVSG MFTEVKPAIL
FDQANTNSNY LPYALIALPY LLASFGYHGN VPGLVKYYNK DSKAVTRSLL YGTLITLAIY
ILWQYVIQGN IPREDFKQII ADGGNIGNLL QQMDNNSDNA AIPQLLNTFS YMALASSFLG
VSLGLFDYLA DYFKFDDTKG GRFKTALITF VPPTVLALIF PNGFLYAIGF AGLAATIWAV
IVPALMARAS RKRYPTSSYR APGGNFLIGF VILFGLINVL AHTFSLFDLL PAYR
//
