ID A0A2D0PM23_ICTPU Unreviewed; 662 AA.
AC A0A2D0PM23;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=DNA polymerase iota isoform X1 {ECO:0000313|RefSeq:XP_017307082.1};
GN Name=poli {ECO:0000313|RefSeq:XP_017307082.1};
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998 {ECO:0000313|RefSeq:XP_017307082.1};
RN [1] {ECO:0000313|RefSeq:XP_017307082.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_017307082.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_017307082.1; XM_017451593.3.
DR AlphaFoldDB; A0A2D0PM23; -.
DR STRING; 7998.ENSIPUP00000034604; -.
DR Ensembl; ENSIPUT00000035964; ENSIPUP00000034604; ENSIPUG00000023243.
DR GeneID; 108255558; -.
DR KEGG; ipu:108255558; -.
DR CTD; 11201; -.
DR OMA; RELMSEW; -.
DR OrthoDB; 2918002at2759; -.
DR Proteomes; UP000221080; Chromosome 22.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0071897; P:DNA biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.40.1170.60; -; 1.
DR Gene3D; 6.10.250.1630; -; 2.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.30.1490.100; DNA polymerase, Y-family, little finger domain; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR036775; DNA_pol_Y-fam_lit_finger_sf.
DR InterPro; IPR017961; DNA_pol_Y-fam_little_finger.
DR InterPro; IPR025527; HUWE1/Rev1_UBM.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR001126; UmuC.
DR PANTHER; PTHR46404; DNA POLYMERASE IOTA; 1.
DR PANTHER; PTHR46404:SF1; DNA POLYMERASE IOTA; 1.
DR Pfam; PF00817; IMS; 1.
DR Pfam; PF11799; IMS_C; 1.
DR Pfam; PF14377; UBM; 2.
DR PIRSF; PIRSF036603; DPol_eta; 3.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF100879; Lesion bypass DNA polymerase (Y-family), little finger domain; 1.
DR PROSITE; PS50173; UMUC; 1.
PE 4: Predicted;
KW DNA synthesis {ECO:0000256|ARBA:ARBA00022634};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 33..243
FT /note="UmuC"
FT /evidence="ECO:0000259|PROSITE:PS50173"
FT REGION 454..523
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 540..662
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 454..486
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 562..576
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 630..644
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 662 AA; 73361 MW; DCC63F2F53532AC0 CRC64;
MESEDEEEVE DSEWITLDTG FPAGRVEDNP RVILHFDMDC FYAQVEMIRN PALRSKPVGV
QQKYLVVTCN YMARAQGVTK MTSVEEALEK CPDLVLVRGE DLTFYREISY KVTELLMSYC
PLVERLGLDE NFVDVTEMVE SRRRNTDISE LSFVGHVYGH DVSGVAVQDH VSLALGSVIA
SELREAVFSR LGLTSCAGVA SSKLLAKLVS GTFKPNQQTT LLPQSVSQLM SSLSGPRRTP
GIGPRTAERL KALGVLSVRD LQLFPLRQLV CEFGEANAKR MQSLACGVDL SPVTPKGPPQ
SLSNEDSFMK ISTLSEAESK ISELLLSLSE RMRKDGRLPQ TMKLSLRRNG APSRWFSRES
RQGPIPTHTA HRIINGCMEA VPQLVSIAMK LLHKLVDVRE PFHLTMLNVC FTNLQAKTSN
RNTISSFFTS AHTHTHTSST HSVCDAPSSF TQPETLCGTT NPQNNKQTSS SLSSSSSSSS
PFIQRPIRAA SSVPPVPERS DPTPDSRSVN IKDLPPDVDP DVFRALPPHI QMELVSGFQE
DPVDRQERHS QSAPPSPRSD DLITQRRGES EEPGDVSAAE RAPGGPDIPP NVDPYVFSQL
PPDMQRELRT EWRRGKPTLK MSPKHTSRRI TTTTTRDKRP AAKRSHSGSL LKYFKPSSDK
RS
//
