ID   A0A2D0PMK8_ICTPU        Unreviewed;      1117 AA.
AC   A0A2D0PMK8;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2023, sequence version 2.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Ataxin-2 isoform X2 {ECO:0000313|RefSeq:XP_017307247.2};
GN   Name=atxn2 {ECO:0000313|RefSeq:XP_017307247.2};
OS   Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC   Ictaluridae; Ictalurus.
OX   NCBI_TaxID=7998 {ECO:0000313|RefSeq:XP_017307247.2};
RN   [1] {ECO:0000313|RefSeq:XP_017307247.2}
RP   IDENTIFICATION.
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_017307247.2};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the ataxin-2 family.
CC       {ECO:0000256|ARBA:ARBA00007503}.
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DR   RefSeq; XP_017307247.2; XM_017451758.3.
DR   AlphaFoldDB; A0A2D0PMK8; -.
DR   OrthoDB; 4269134at2759; -.
DR   Proteomes; UP000221080; Chromosome 22.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   InterPro; IPR009818; Ataxin-2_C.
DR   InterPro; IPR045117; ATXN2-like.
DR   InterPro; IPR009604; LsmAD_domain.
DR   InterPro; IPR047575; Sm.
DR   InterPro; IPR025852; SM_dom_ATX.
DR   PANTHER; PTHR12854; ATAXIN 2-RELATED; 1.
DR   PANTHER; PTHR12854:SF11; ATAXIN-2; 1.
DR   Pfam; PF06741; LsmAD; 1.
DR   Pfam; PF07145; PAM2; 1.
DR   Pfam; PF14438; SM-ATX; 1.
DR   SMART; SM01272; LsmAD; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
DR   PROSITE; PS52002; SM; 1.
PE   3: Inferred from homology;
FT   DOMAIN          63..140
FT                   /note="Sm"
FT                   /evidence="ECO:0000259|PROSITE:PS52002"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          155..182
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          283..338
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          358..715
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          910..1030
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        162..177
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        371..392
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        441..470
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        490..516
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        538..556
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        578..592
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        599..613
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        614..629
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        642..681
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        682..697
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        910..945
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        965..1015
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1117 AA;  119724 MW;  08E2A6B1A813550B CRC64;
     MSMKQTGGNR KPGSGSSSGA AAASGAGGCA GAAAGRHSLT RGRNSAKAHS APVAFSGVYA
     NMRMVHVLTS VVGAKCELKV KNGAIYEGVF KTYGPECDLV LDAAHRKSPE PNVGPRREDI
     VESIIFKASD VVVVHFKDVD LSYAKKVSSE QDNLTDNPLS ARLNGEHKEK DLEPWDGGDQ
     HVSGSLESLD TDLSNGWDPD DMFKYNEETY GVKSTYDSSL SSYTVPLERD NSEEFLKREA
     RAAQLAEEIE ASATYKARVA LENDERSEEE KYSAVVRDAH TVGRENKYIP PGQRNREAGL
     SWGAGRQNSP RLVQCNPGPP TPRASPHDYN TLAGVDQRVV NGGSPHWFSR CPSPSSYPSS
     RYQSGPNASL PTRPPSRPPS RPSRPPSHPS AHGSPAPLST LPKRLSLEGP PRMSPKSQRT
     PRAHRVPSCR GAPGVEFMSQ GASGEASTTP PARSSPSGGT WSSVVSGGHR PRSPRQTIVG
     GPPPGPSSLS SPQAGTVPVD SVATPTLATS PISASPAPIM SAIPVTEAKE IRHNSPSANK
     ENVKPVESSP SSRPVSKGFP SMPPDHRKQI DNLKKFSVDF RLQSSSNPDL GVEPMMTKSP
     RDSGEKFKES PSDKSMTEST GSKVCSESPG SEEVSAALGA DSSGSKPGTP SPSPSSSTPS
     TEQKRVPDVT SQGVQTSSPA AMKSDDKEDK KDPLPESVRK STLNPNAKEF NPRPFCTPQI
     QGVPKLSLHR GLCLPAPRRL CLRQWMFVDV NFSPKPATTP TLTRPQGQPS PSIMVQQPPA
     VYSQPMCFPQ MYPLTPVSPG VQKSIIWKPP AMYHVQVPHM TVSQTKPYRT VPNIQQQRPD
     QHHPAGTSPM MHPATAAGPP ILAQSPAYST QYFTCSPQQF SSQTLMQQMP HYQSQAQHVF
     SPVMQGGARM ITSSHGQPNL ASSSATQYGE QTHTMYVSAP IPQQYQHPGA TLHPHAPQPP
     QPSATPTGQA QQSGQHAGTS HAAASPVQHP QHQASLHLAS AAPPQQQMYS ALTPTPPSMT
     PGPAPQSPQA VYIHPQQVQH SYNPNHMAHM QQAHMQSGMH VPQHHGTPSH PVMLMATQAG
     PQPPLPQNTL NPIPVSSTTH FSYMAHPSVQ PHHQQQL
//