ID A0A2D0PMV1_ICTPU Unreviewed; 423 AA.
AC A0A2D0PMV1;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Keratin, type 1, gene c5 isoform X1 {ECO:0000313|RefSeq:XP_017306746.1};
GN Name=krt1-c5 {ECO:0000313|RefSeq:XP_017306746.1};
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998 {ECO:0000313|RefSeq:XP_017306746.1};
RN [1] {ECO:0000313|RefSeq:XP_017306746.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_017306746.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|RuleBase:RU000685}.
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DR RefSeq; XP_017306746.1; XM_017451257.3.
DR AlphaFoldDB; A0A2D0PMV1; -.
DR Ensembl; ENSIPUT00000027447; ENSIPUP00000026365; ENSIPUG00000017851.
DR GeneID; 108255341; -.
DR KEGG; ipu:108255341; -.
DR CTD; 767716; -.
DR OrthoDB; 4640531at2759; -.
DR Proteomes; UP000221080; Chromosome 22.
DR GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR002957; Keratin_I.
DR PANTHER; PTHR23239; INTERMEDIATE FILAMENT; 1.
DR PANTHER; PTHR23239:SF354; KERATIN, TYPE I CYTOSKELETAL 18; 1.
DR Pfam; PF00038; Filament; 1.
DR PRINTS; PR01248; TYPE1KERATIN.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 2.
DR PROSITE; PS00226; IF_ROD_1; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|RuleBase:RU000685}.
FT DOMAIN 68..379
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT REGION 16..42
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 72..106
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 177..222
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 260..371
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 423 AA; 48075 MW; B17A09D36482ABE4 CRC64;
MTASISVHTY SAARQPSFSS SSLRDGGIRG RSKAPVLSST STRSLYRSMS VGNGLNNLSN
LSLNGTSEKE TMKGLNDRLA SYLSKVRSLE KSNADLELKI KQLMLERMPK GHDIEGMMAQ
AHAIGQEVRK KTLANARIML EIDNAKLAAD DFRIKWESEA ALCQSVERDC VALRRAKQEH
DQIITTLRGD LESLKEELYF LKKNHEEDMT TLKARLANEQ VNVEVDAAPG PHLGTVMAEL
RCQYEGIARK NKEDAEMWCL KKLETLQSEV KESNEALRSA QNELNERRRF LQGLEVELDS
LHKQVSVLEG NLGETSHKYT LEMEHMQGTL TQLEEELSQL RLDMQRIKTD YEQLLRVKQN
LELEIATYRR LLEGEDVVKE TPTPKKEPEV KTRKIVKVVT QTMVNGKVVE ESSEVEQFEE
RNK
//
