ID   A0A2D0PVP2_ICTPU        Unreviewed;       955 AA.
AC   A0A2D0PVP2;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2023, sequence version 2.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Sorting nexin-13 isoform X1 {ECO:0000313|RefSeq:XP_017310087.2};
GN   Name=snx13 {ECO:0000313|RefSeq:XP_017310087.2};
OS   Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC   Ictaluridae; Ictalurus.
OX   NCBI_TaxID=7998 {ECO:0000313|RefSeq:XP_017310087.2};
RN   [1] {ECO:0000313|RefSeq:XP_017310087.2}
RP   IDENTIFICATION.
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_017310087.2};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the sorting nexin family.
CC       {ECO:0000256|ARBA:ARBA00010883}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   RefSeq; XP_017310087.2; XM_017454598.3.
DR   AlphaFoldDB; A0A2D0PVP2; -.
DR   KEGG; ipu:108257130; -.
DR   OrthoDB; 5392990at2759; -.
DR   Proteomes; UP000221080; Chromosome 24.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0043226; C:organelle; IEA:UniProt.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR   CDD; cd06873; PX_SNX13; 1.
DR   CDD; cd08719; RGS_SNX13; 1.
DR   Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR   Gene3D; 1.10.167.10; Regulator of G-protein Signalling 4, domain 2; 1.
DR   InterPro; IPR003114; Phox_assoc.
DR   InterPro; IPR001683; PX_dom.
DR   InterPro; IPR036871; PX_dom_sf.
DR   InterPro; IPR016137; RGS.
DR   InterPro; IPR036305; RGS_sf.
DR   InterPro; IPR044926; RGS_subdomain_2.
DR   InterPro; IPR037437; SNX13_PX.
DR   InterPro; IPR037896; SNX13_RGS.
DR   InterPro; IPR013937; Sorting_nexin_C.
DR   PANTHER; PTHR22775; SORTING NEXIN; 1.
DR   PANTHER; PTHR22775:SF3; SORTING NEXIN-13; 1.
DR   Pfam; PF08628; Nexin_C; 1.
DR   Pfam; PF00787; PX; 1.
DR   Pfam; PF02194; PXA; 1.
DR   Pfam; PF00615; RGS; 1.
DR   SMART; SM00312; PX; 1.
DR   SMART; SM00313; PXA; 1.
DR   SMART; SM00315; RGS; 1.
DR   SUPFAM; SSF64268; PX domain; 1.
DR   SUPFAM; SSF48097; Regulator of G-protein signaling, RGS; 1.
DR   PROSITE; PS50195; PX; 1.
DR   PROSITE; PS51207; PXA; 1.
DR   PROSITE; PS50132; RGS; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..23
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        30..52
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          98..286
FT                   /note="PXA"
FT                   /evidence="ECO:0000259|PROSITE:PS51207"
FT   DOMAIN          375..498
FT                   /note="RGS"
FT                   /evidence="ECO:0000259|PROSITE:PS50132"
FT   DOMAIN          561..683
FT                   /note="PX"
FT                   /evidence="ECO:0000259|PROSITE:PS50195"
SQ   SEQUENCE   955 AA;  111096 MW;  E9A0C9798DAEB3C4 CRC64;
     MFVFQANLSV WGWGGLGILL FLITFGPFAI FYLAFYIFCF LGGGFAVTLL FGKTNSEKHL
     EKCEHSYLPP TPTGIAKTLE ELKQETKPIK IDRRLTGSNF IDEPLQQVIQ FALRDYIQYW
     YYTLSEDESF LLEIRQTVQN ALVQFSTRSK EVDWQPYFTT RLVDDFATHL RVFRKAQERL
     NEREDPKQRE APEELLDAFF ETEVEMERKI CRDVVCTSHG DEEGFLRDLC EVLLYLLLPP
     GDFHNKNMRY FLREILARGV LLPLINQLSD PDYINQFIIW MIRDSSCNYE AFMNILKLTD
     KTAELEAVKD KVLEELQYLR SLDTAGDDIN TIKNQINSLL FVKKVCETRI QRLQSGKDVD
     AMKLAANFGK LCIIPLDHIL VHNIALQFFM DYMQQMGGQA DLFFWLTVEG YRVTAQQQLE
     VLQSWKKDGR KQTGQTKDLL KAAALGVYEQ YLSEKASPRV QVDRACVDRL AEKLNKEDPT
     PEIFDDIQRK VYDMMLKDER FYPSFKQHPL YVRMLAELDM LKEPSYRGSD DGDAESFNGS
     PTGSINLSLD DLTNATTDES VQLHAFISDT GVCNDHGKTY ALYAITVFRK NPDGSEDTWK
     TYRRYSDFHD FHMRITEQFE NLSSILKLPG KKTFNNMDRD FLERRKKDLN AYLQLLLNPE
     LVKACPMLIG HVHDFLENKA YSKGKGDFAR KMDTFVNPLR SSMRNVSNAV KSLPDSLAEG
     MTKVTDNVGR MGERLGQDLR QSIFKVPPLI PKSDIDPEHC RVSAQLDDNV DDNIPLRVML
     LLMDEVFDLK ERNQWLRRNI KNLLQQLIRA TYGDTINRKI VDHVDFMTSP EQVADYVKRF
     RDSYWPNGIL AETPPCRDKS IRMRTRVAAK TNLLGIMPDE LKHIIGAETT RKGILRVFEM
     FQHQQLNRRL VYVFLEGFLE TMFPQYKFPE LFVKLHSRSP RIRTYSQKVR TLQKR
//