ID A0A2D0PWX2_ICTPU Unreviewed; 581 AA.
AC A0A2D0PWX2;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Epsin-2 {ECO:0000313|RefSeq:XP_017310521.1, ECO:0000313|RefSeq:XP_017310522.1};
GN Name=epn2 {ECO:0000313|RefSeq:XP_017310521.1,
GN ECO:0000313|RefSeq:XP_017310522.1};
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998 {ECO:0000313|RefSeq:XP_017310522.1};
RN [1] {ECO:0000313|RefSeq:XP_017310521.1, ECO:0000313|RefSeq:XP_017310522.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_017310521.1,
RC ECO:0000313|RefSeq:XP_017310522.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the epsin family.
CC {ECO:0000256|ARBA:ARBA00010130}.
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DR RefSeq; XP_017310521.1; XM_017455032.3.
DR RefSeq; XP_017310522.1; XM_017455033.3.
DR RefSeq; XP_017310523.1; XM_017455034.1.
DR STRING; 7998.ENSIPUP00000023792; -.
DR Ensembl; ENSIPUT00000024797; ENSIPUP00000023783; ENSIPUG00000016083.
DR Ensembl; ENSIPUT00000024806; ENSIPUP00000023792; ENSIPUG00000016083.
DR Ensembl; ENSIPUT00000024827; ENSIPUP00000023813; ENSIPUG00000016083.
DR GeneID; 108257348; -.
DR KEGG; ipu:108257348; -.
DR CTD; 22905; -.
DR OMA; YLIKCGS; -.
DR OrthoDB; 1532at2759; -.
DR Proteomes; UP000221080; Chromosome 24.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR CDD; cd16990; ENTH_Epsin; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR InterPro; IPR013809; ENTH.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR003903; UIM_dom.
DR PANTHER; PTHR12276:SF50; EPSIN-2; 1.
DR PANTHER; PTHR12276; EPSIN/ENT-RELATED; 1.
DR Pfam; PF01417; ENTH; 1.
DR SMART; SM00273; ENTH; 1.
DR SMART; SM00726; UIM; 2.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR PROSITE; PS50942; ENTH; 1.
DR PROSITE; PS50330; UIM; 2.
PE 3: Inferred from homology;
KW Lipid-binding {ECO:0000256|ARBA:ARBA00023121}.
FT DOMAIN 12..144
FT /note="ENTH"
FT /evidence="ECO:0000259|PROSITE:PS50942"
FT REGION 144..222
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 253..318
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 337..385
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 152..221
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 253..272
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 581 AA; 61777 MW; 2DA1A616F6663156 CRC64;
MPSSTIRRQM KNVVNNYSDA EKKVREATSN DPWGPSSSLM SEISDLTYNV VAFSEIMSMI
WKRLNDHGKN WRHVYKALTL LDYLIKTGSE RVALQCKENI FAIQTLKDFQ YVDRDGKDQG
INVREKSKQL VVLLKDDDRL KGERSQALKT KERMAQVATS VGSSHQIGFG RGSSQPNLST
SYSEEYGRSE GSPASYHGST SPNASSELEQ ARPQTSGEEE LQLQLALAMS REAAEQEERM
RRGDDLRLQM ALEESRKDSV KGPKKKKEPQ STLMDLIDAV PGGPVDPWGA GARAAAAAPA
PATAPTSDPW QSYGSVNKPA APVDPWGLPA SAPSVSPIKN SDPWGSSPAL TVADPWGSGP
AARPKAPGPG SFDLFSTSNG TSKDDLDDFD SLRSSMMSGV GKGSSAMPLQ TSKSASPDLF
DLQPTRNTPE SFLGPNAALV NLDSLITKPA QPAPVSNPFL AGGATPAPPA QVQVNPFQVN
QPQPPTLNQM RVSPMMGLSG QGLSSLSQRS NEPMPLSSLP PAGAVGMGPV GGMAPIVPMG
QMMPSMGLPA SMSIPQPLMS GVLPPTGTAT QATGPTNPFL L
//
