ID A0A2D0Q0W0_ICTPU Unreviewed; 1481 AA.
AC A0A2D0Q0W0;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Mitogen-activated protein kinase-binding protein 1 isoform X2 {ECO:0000313|RefSeq:XP_017311934.1};
GN Name=LOC108258089 {ECO:0000313|RefSeq:XP_017311934.1};
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998 {ECO:0000313|RefSeq:XP_017311934.1};
RN [1] {ECO:0000313|RefSeq:XP_017311934.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_017311934.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_017311934.1; XM_017456445.3.
DR GeneID; 108258089; -.
DR OrthoDB; 1220745at2759; -.
DR Proteomes; UP000221080; Chromosome 25.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 4.
DR InterPro; IPR024977; Apc4-like_WD40_dom.
DR InterPro; IPR013979; TIF_beta_prop-like.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR44813; MITOGEN-ACTIVATED PROTEIN KINASE-BINDING PROTEIN 1; 1.
DR PANTHER; PTHR44813:SF1; MITOGEN-ACTIVATED PROTEIN KINASE-BINDING PROTEIN 1; 1.
DR Pfam; PF12894; ANAPC4_WD40; 1.
DR Pfam; PF08662; eIF2A; 1.
DR Pfam; PF00400; WD40; 3.
DR SMART; SM00320; WD40; 12.
DR SUPFAM; SSF50978; WD40 repeat-like; 2.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|RefSeq:XP_017311934.1};
KW Transferase {ECO:0000313|RefSeq:XP_017311934.1};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 75..193
FT /note="Translation initiation factor beta propellor-like"
FT /evidence="ECO:0000259|Pfam:PF08662"
FT DOMAIN 470..523
FT /note="Anaphase-promoting complex subunit 4-like WD40"
FT /evidence="ECO:0000259|Pfam:PF12894"
FT REPEAT 692..733
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 804..839
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 871..918
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 933..1004
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1071..1105
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1165..1240
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1278..1305
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 818..834
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 871..893
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 952..969
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 986..1004
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1071..1090
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1180..1206
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1214..1240
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1281..1305
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1481 AA; 162361 MW; A15F4D61E20B745B CRC64;
MEGSSIKNRI KNLLRSPSIK LKKNRRLEKE NLTNKLTLER VLGITTSGSC GLTCDPCSGT
VAYLAGCVVV LLNPTKNGQQ HIINTSRKTI TAVAFSSDGK YLVTGEYGHL PAVRVWDVAD
GSQVAELQEH KYGVACVAFS PNSKYIVSIG YQHDMSVNVW AWKKNMLVAA NKVSSKVTAV
SFSEDSSYFV TAGNRHVRYW YLEPCNSNKQ LTAPVPLLGR SGLLGELQNN NFCDVACGRG
GKSESTFCIT SSGLLCEFNE RRMLDKWVDL RTSTASALFV TEELIFCACA DGTVRVFSPS
DLHFICTLPR PHHLGTDVSA VSQTSHLFSN KPDARYPDSV AVTYDPVNFW LSCVYNDHSL
YVWDVQDLRR VGKVYSGLYH SAWVWDVQIY PGAKEEPLTG LTSSGLFFSC SADSTVRMWS
TEPQINPANS NLLSSDLRKV IYTASNSTCL LDTEGTGTSC TEKPEEQPAE SRTGIRTICV
SPDGKHLASG DQNGTLRIHE LNTMEEVLKV EVHDSEILCM EYSKPETGMK LLATAGRDRL
IRVLDVEEDY SLLQTLDEHS SSITAVRFAA NEGKVRMISC GADKSVYFRT AHRTFRGVKF
KRTHHVVRKS SLHDMNVDPT CKYAAVGCQD RHVRVFNINS GKQKMSFKGS RAEDGSLLRV
QMDPSGLYVA TSCSDKNLSL FDFRTGECLA AAFGHSEIIT GIKFTSDCRH LISASGDSCI
FIWRLAPEMS MNMRERLDQF THATSGPAFA ESVIRRASTS SLAMHSTLSL LTYSSESEED
YNEETFEDIQ TPDYHDLHQT SLEEDQGASD DMNDWDSSKF QESSTGSSVS EQSLPEVPHR
RKRWNCRIGS FELMVKSMLE LHQFESFSKP GSPLRGSTGQ LSDQACSSTA SLHKDTKWSK
RRQARPDSSW LGATSSPEPE VVILSSELCP STDSLPGAYQ VQEEESQESH SPDRGSSMGY
ASGGSSPEQA YEGSDDPELL SNDEDDEEVA RGRPFHQPES PEQESFLKKH FETLADTNDT
GNEPKPQSST SVCFFSHGST PRRLSQFLSK TDEKSEKCAV LKPLVSTVRP LQKDNGQGAN
LDQRADACSS EQLHSAPKRR KTCRMQNTTS PISMSRVMSP ADKSLLNSMS ALGLTANSRK
CVTTSLLKQA PGPSTPEVLA DRNDSILRHP SPTDSPSPLP WESPNTNRRL KVRSYMSPTT
SSRAKISRSM SHKEGLHLNL SSGQTSPCPG SSPSSPFHAS SLLQSLSAPL PGPCNPAVPR
LSYGGCSPNP TAKITKARVS ARMSNPLSEY PSRSTPTPST DSAALSNNVT KTGVQHGDKC
YTKGQVEPTK NVFPIPVSQS VSVKDSLSPK TSAHTPQHPL VDVQAYSVAC KSQSDQAEPS
MNLETCRQAA AELYNSVKKA TQLYTVVSSC VGNVGSELQA MDRVLMEALF MARSELEAVP
GLTPASAVTA LGEGEEKTLA LLEQYSQLLL QSVEKRLEHK I
//
