ID A0A2D0Q2C4_ICTPU Unreviewed; 614 AA.
AC A0A2D0Q2C4;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Interferon-induced GTP-binding protein Mx1-like isoform X1 {ECO:0000313|RefSeq:XP_017312883.1};
GN Name=LOC108258633 {ECO:0000313|RefSeq:XP_017312883.1};
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998 {ECO:0000313|RefSeq:XP_017312883.1};
RN [1] {ECO:0000313|RefSeq:XP_017312883.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_017312883.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the TRAFAC class dynamin-like GTPase
CC superfamily. Dynamin/Fzo/YdjA family. {ECO:0000256|RuleBase:RU003932}.
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DR RefSeq; XP_017312883.1; XM_017457394.3.
DR AlphaFoldDB; A0A2D0Q2C4; -.
DR STRING; 7998.ENSIPUP00000006856; -.
DR GeneID; 108258633; -.
DR KEGG; ipu:108258633; -.
DR OrthoDB; 1052588at2759; -.
DR Proteomes; UP000221080; Chromosome 26.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR CDD; cd08771; DLP_1; 1.
DR Gene3D; 1.20.120.1240; Dynamin, middle domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR022812; Dynamin.
DR InterPro; IPR001401; Dynamin_GTPase.
DR InterPro; IPR019762; Dynamin_GTPase_CS.
DR InterPro; IPR045063; Dynamin_N.
DR InterPro; IPR000375; Dynamin_stalk.
DR InterPro; IPR030381; G_DYNAMIN_dom.
DR InterPro; IPR003130; GED.
DR InterPro; IPR020850; GED_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11566; DYNAMIN; 1.
DR PANTHER; PTHR11566:SF225; INTERFERON-INDUCED GTP-BINDING PROTEIN MXA-RELATED; 1.
DR Pfam; PF01031; Dynamin_M; 1.
DR Pfam; PF00350; Dynamin_N; 1.
DR Pfam; PF02212; GED; 1.
DR PRINTS; PR00195; DYNAMIN.
DR SMART; SM00053; DYNc; 1.
DR SMART; SM00302; GED; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00410; G_DYNAMIN_1; 1.
DR PROSITE; PS51718; G_DYNAMIN_2; 1.
DR PROSITE; PS51388; GED; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|RuleBase:RU003932};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU003932}.
FT DOMAIN 29..292
FT /note="Dynamin-type G"
FT /evidence="ECO:0000259|PROSITE:PS51718"
FT DOMAIN 529..614
FT /note="GED"
FT /evidence="ECO:0000259|PROSITE:PS51388"
FT COILED 557..610
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 614 AA; 71025 MW; 50A13F95449045D2 CRC64;
MSLSEQYEEK VRPYIDLIDS LRVFGVEKDL ALPAIAVIGD QSLGKSSVLE ALSGVALPRG
SGIVTRCPLE LKLKKSRQED FWHGKIKYKD IERDITDPTD VERSIRKAQN EIAGALGMSD
ELISLEVTST NAPDLTFIDL PGIVHVPVKG QPEDIGKQIK SLIKKFITKQ DTIILVVVDI
KTTEALKMVE EVDLNGVLTK PDLVDEVKED EVMSVINNKI TYPIKGYMVV RCQGQQEIMD
RISLYEAIKK EKGFFIEHPH FRMPYKEGKA TIPKLAEKLT VELVLHIEKS LPQLKDQIQV
MLAETQTELD RYNSEPPTDP EQRMDFLTDK ITAFTQDAIN LMIGEETKSM PHVNIFSSLR
RQFNDWKMDL DKTAETFNKG IEKEVKEYEE NYRGRELRGF INYKTFEIIL KDKIKQLEKP
AIRRMKDISD FIRNEFFQLA QSNFLDFPNL LKMTKTKIEN IKQLKESEAE TMLKTQFKME
LMIYTQDSVY TDTLNMRNRT EEEEERQSHG VAHPPCNSLY NYSDTEDALE ELTHHLKSYY
SIASKRLADQ VPLVIKYKVL QESAAQLQRE MRQLIKNYNI NDLLEEDYEI NIKRNNLESS
QKRLKEALVK LVLL
//
