ID   A0A2D0Q2E1_ICTPU        Unreviewed;       542 AA.
AC   A0A2D0Q2E1;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2023, sequence version 2.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Hepatitis A virus cellular receptor 1 isoform X5 {ECO:0000313|RefSeq:XP_017311856.2};
GN   Name=LOC108258075 {ECO:0000313|RefSeq:XP_017311856.2};
OS   Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC   Ictaluridae; Ictalurus.
OX   NCBI_TaxID=7998 {ECO:0000313|RefSeq:XP_017311856.2};
RN   [1] {ECO:0000313|RefSeq:XP_017311856.2}
RP   IDENTIFICATION.
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_017311856.2};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_017311856.2; XM_017456367.3.
DR   AlphaFoldDB; A0A2D0Q2E1; -.
DR   OrthoDB; 4268756at2759; -.
DR   Proteomes; UP000221080; Chromosome 25.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR013106; Ig_V-set.
DR   PANTHER; PTHR46608:SF3; HEPATITIS A VIRUS CELLULAR RECEPTOR 1 HOMOLOG ISOFORM X1; 1.
DR   PANTHER; PTHR46608; T-CELL IMMUNOGLOBULIN AND MUCIN DOMAIN-CONTAINING PROTEIN 4; 1.
DR   Pfam; PF07686; V-set; 1.
DR   SMART; SM00409; IG; 1.
DR   SUPFAM; SSF48726; Immunoglobulin; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000313|RefSeq:XP_017311856.2};
KW   Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           23..542
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5039905769"
FT   TRANSMEM        481..504
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          31..113
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   REGION          351..375
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   542 AA;  59568 MW;  0848401E98A6C971 CRC64;
     MNQLHCWISS FGLLLCLTVC TCSPMNIWRI EGQDVTIPCR YNSHYHGTCD VCWMRGSIPR
     SGCGNQIIYA TGKNVVMRGN RRYQLNGNLQ KGDASLTILN ARISDSGKYG CRIHVPGWFN
     DIKMEVYLII TEAPKPSTTL RHITTTTRVP THGPVLTTQD DISTVPEHVT TSHTGPVLTT
     QDDISTVPEH VTTSHTETQQ TFTTLEYVTT TTHIPTQRPD LTTQDETTTA HEIVTTKHTE
     TQQTTSTLGY VTTVTHIPTQ GPVLTTQDET STAPEHVTAK HTGPVLTTQD DISTVPEHVT
     TSHTETQQTF TTLEYVTTTT HIPTQRPDLT TQDETTTAHE IVTTKHTGPV LTTQDETSTA
     PEHVTTKHTG PVLTTQDDIS TVPEHVTTSH TGPDLTTQDE TTTAHEIVTT KHTETQQTTS
     TLGYVTTVTH IPTQGPVLTT QDETSTAPEH VTTKHTVVIA ENDIDVSSSE KEMLVNEDPG
     VLPAILVPVI LILAVLGISA VYFISKQKRR FRSTIELAKN SSVNYNNLDS SVTLPITNLF
     NN
//