ID A0A2D0Q5V2_ICTPU Unreviewed; 1012 AA.
AC A0A2D0Q5V2;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Adhesion G-protein coupled receptor G2 isoform X3 {ECO:0000313|RefSeq:XP_017313081.1};
GN Name=LOC108258733 {ECO:0000313|RefSeq:XP_017313081.1};
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998 {ECO:0000313|RefSeq:XP_017313081.1};
RN [1] {ECO:0000313|RefSeq:XP_017313081.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_017313081.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR RefSeq; XP_017313081.1; XM_017457592.3.
DR AlphaFoldDB; A0A2D0Q5V2; -.
DR GeneID; 108258733; -.
DR OrthoDB; 4263146at2759; -.
DR Proteomes; UP000221080; Chromosome 26.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR GO; GO:0009653; P:anatomical structure morphogenesis; IEA:UniProt.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.
DR GO; GO:0048731; P:system development; IEA:UniProt.
DR Gene3D; 2.60.220.50; -; 3.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR032471; GAIN_dom_N.
DR InterPro; IPR046338; GAIN_dom_sf.
DR InterPro; IPR017981; GPCR_2-like_7TM.
DR InterPro; IPR000832; GPCR_2_secretin-like.
DR InterPro; IPR000203; GPS.
DR PANTHER; PTHR12011:SF472; ADHESION G PROTEIN-COUPLED RECEPTOR E1-RELATED; 1.
DR PANTHER; PTHR12011; ADHESION G-PROTEIN COUPLED RECEPTOR; 1.
DR Pfam; PF00002; 7tm_2; 1.
DR Pfam; PF16489; GAIN; 1.
DR Pfam; PF01825; GPS; 1.
DR SMART; SM00303; GPS; 3.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS50261; G_PROTEIN_RECEP_F2_4; 1.
DR PROSITE; PS50221; GPS; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|RefSeq:XP_017313081.1};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..1012
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5013265814"
FT TRANSMEM 755..778
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 790..813
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 873..901
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 921..945
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 951..974
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 738..975
FT /note="G-protein coupled receptors family 2 profile 2"
FT /evidence="ECO:0000259|PROSITE:PS50261"
SQ SEQUENCE 1012 AA; 113061 MW; F4B4B66A72DF037D CRC64;
MILLLKKATL LLVTTITMCA TSSFQDFVSD CWTLPEYCQA NLTAECATDY LDNVKNCIQK
ELSKADLERY LNTIMSLATN VTKGTADHNN LNSFGKAVLD VNKQLVSVDL MKTDNNIKII
AQNLEVQVFM IGSKSNVYYS PKLNYVSADV NLTQLPQMNA VSVSRSVAVA LMSYTNVTDL
LKPSFFNTVT SATNTTIMSA VVSAVLPITT NKGLTIPVDF TLTHITPLDP EAFLSCMDWE
TNTWDTCSLT HTNSTMTVCS CNRLTTLALI SQTDPCRFNL TVQCAMAFLN QRQYNIAQDL
PQETVERYLN TIMNLTAGVM NKYEQNSYGN VLMDVTEKLV SALVKKTDNY DSTNITLHNL
EVRVFMVGPR VSLTKTPTLI TSSATMDINL TEISKKNEGS AAVAFMSYTN MADILGPKFN
TFTNTNKTVM SMVVSATLPK TTNTELTEPV NFTLKHIKEL APENILTCMN WHENTWKAND
CNVIETNSSH TVCSCSRLGT IMLIMQTDPC IGSLTGLCAK NFLLQIPANI PEELPEKIVK
NYLSIMMNLT TRVLVSVPDQ KYLMSYGDYL LNITAQLVST LVRKRDTYSN ISMSLQNFDV
QVFMVFGLNV SSSEIPQFSI RNTSMDIDLV GISKNNNGST AVAFMSYTNM TNILKPTLFK
TNTNTSKTMM STVVSALLPK TTNTSLNKPV NFTFKHISDL DPEGILSCVC WKNEAWLVEG
CRIIQTNSSH TVCSCDRLAT FALIMQTDPC RSDRLMNMLI AVAIIVGLVF LSLSILTFSF
YSRNPVTNAA LINLCINLLL FHLLSLIKTL FLAQIHALNL SDIRSNPEEV FSWRWLTVIG
YLVPLGVLGM SSVSFPEGYI DEECWENEDK SVIFIFAGPV LFTVTVNLIA YLLIIIIIVI
FTVKHLKDEV LQMSNTSYRN LLMCLMFRSL TQFIVLVCYW ILLYIPSKDG VLYHAFQLLN
SQQGTLIFLV HCLLNQEIRQ KYRKVLCAFC LTNNPVTTSR SVRGQPEASQ NN
//
