ID A0A2D0Q646_ICTPU Unreviewed; 185 AA.
AC A0A2D0Q646;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 isoform X1 {ECO:0000313|RefSeq:XP_017313778.1, ECO:0000313|RefSeq:XP_017313779.1};
GN Name=ptpmt1 {ECO:0000313|RefSeq:XP_017313778.1,
GN ECO:0000313|RefSeq:XP_017313779.1};
GN Synonyms=ptpm1 {ECO:0000313|RefSeq:XP_017313778.1,
GN ECO:0000313|RefSeq:XP_017313779.1};
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998 {ECO:0000313|RefSeq:XP_017313779.1};
RN [1] {ECO:0000313|RefSeq:XP_017313778.1, ECO:0000313|RefSeq:XP_017313779.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_017313778.1,
RC ECO:0000313|RefSeq:XP_017313779.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
CC -!- PATHWAY: Phospholipid metabolism. {ECO:0000256|ARBA:ARBA00025707}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_017313778.1; XM_017458289.3.
DR RefSeq; XP_017313779.1; XM_017458290.3.
DR Ensembl; ENSIPUT00000036754; ENSIPUP00000035366; ENSIPUG00000023712.
DR GeneID; 100528459; -.
DR CTD; 114971; -.
DR OMA; NAHWRTV; -.
DR OrthoDB; 1046951at2759; -.
DR Proteomes; UP000221080; Chromosome 27.
DR GO; GO:0008962; F:phosphatidylglycerophosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
DR GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR GO; GO:0008654; P:phospholipid biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd14524; PTPMT1; 1.
DR Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR InterPro; IPR000340; Dual-sp_phosphatase_cat-dom.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR InterPro; IPR042165; PTPMT1.
DR InterPro; IPR044596; PTPMT1-like.
DR InterPro; IPR016130; Tyr_Pase_AS.
DR InterPro; IPR000387; Tyr_Pase_dom.
DR InterPro; IPR020422; TYR_PHOSPHATASE_DUAL_dom.
DR PANTHER; PTHR46712; PHOSPHATIDYLGLYCEROPHOSPHATASE AND PROTEIN-TYROSINE PHOSPHATASE 1; 1.
DR PANTHER; PTHR46712:SF1; PHOSPHATIDYLGLYCEROPHOSPHATASE AND PROTEIN-TYROSINE PHOSPHATASE 1; 1.
DR Pfam; PF00782; DSPc; 1.
DR SMART; SM00195; DSPc; 1.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR PROSITE; PS00383; TYR_PHOSPHATASE_1; 1.
DR PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
DR PROSITE; PS50054; TYR_PHOSPHATASE_DUAL; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023209};
KW Phospholipid biosynthesis {ECO:0000256|ARBA:ARBA00023209};
KW Phospholipid metabolism {ECO:0000256|ARBA:ARBA00023264};
KW Protein phosphatase {ECO:0000256|ARBA:ARBA00022912}.
FT DOMAIN 28..179
FT /note="Tyrosine-protein phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS50054"
FT DOMAIN 100..168
FT /note="Tyrosine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS50056"
SQ SEQUENCE 185 AA; 21018 MW; EACDD40FCC1C34BD CRC64;
MSGLLARILF YPTLAYNVMM EKISSRRWFD RVDQTVILGA LPFRSMTEEL VQAENVRGVV
TMNEEYETEF FCNSAEEWKA EGVEQIRLST VDLTGVPSLE HIHRGVEFVL KHRDQGTSVY
IHCKAGRSRS ATLAAAYLIR LHCWSTDKAC KQLAAVRPHV LIRSAQRDML DKYHKQVCGP
DSSGV
//
