ID   A0A2D0Q696_ICTPU        Unreviewed;       823 AA.
AC   A0A2D0Q696;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   SubName: Full=ARL14 effector protein {ECO:0000313|RefSeq:XP_017314223.1};
GN   Name=arl14ep {ECO:0000313|RefSeq:XP_017314223.1};
OS   Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC   Ictaluridae; Ictalurus.
OX   NCBI_TaxID=7998 {ECO:0000313|RefSeq:XP_017314223.1};
RN   [1] {ECO:0000313|RefSeq:XP_017314223.1}
RP   IDENTIFICATION.
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_017314223.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   RefSeq; XP_017314223.1; XM_017458734.3.
DR   AlphaFoldDB; A0A2D0Q696; -.
DR   STRING; 7998.ENSIPUP00000027013; -.
DR   GeneID; 108259338; -.
DR   KEGG; ipu:108259338; -.
DR   CTD; 120534; -.
DR   OrthoDB; 75559at2759; -.
DR   Proteomes; UP000221080; Chromosome 27.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   InterPro; IPR029264; ARF7EP_C.
DR   InterPro; IPR008906; HATC_C_dom.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR006612; THAP_Znf.
DR   InterPro; IPR003656; Znf_BED.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   PANTHER; PTHR46481:SF4; ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 39; 1.
DR   PANTHER; PTHR46481; ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4; 1.
DR   Pfam; PF14949; ARF7EP_C; 1.
DR   Pfam; PF05699; Dimer_Tnp_hAT; 1.
DR   Pfam; PF05485; THAP; 1.
DR   Pfam; PF02892; zf-BED; 1.
DR   SMART; SM00692; DM3; 1.
DR   SMART; SM00980; THAP; 1.
DR   SMART; SM00614; ZnF_BED; 1.
DR   SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 1.
DR   SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR   SUPFAM; SSF140996; Hermes dimerisation domain; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR   PROSITE; PS50808; ZF_BED; 1.
DR   PROSITE; PS50950; ZF_THAP; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW   ProRule:PRU00309}; Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00309}.
FT   DOMAIN          1..57
FT                   /note="BED-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50808"
FT   DOMAIN          591..672
FT                   /note="THAP-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50950"
FT   REGION          469..503
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          682..748
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        485..503
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        682..696
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        711..743
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   823 AA;  92271 MW;  F6109EDCBB733EF3 CRC64;
     MSAVWKHFKV SEKDGRMAVC RQCSAELSRG GTSGKTYSTT SLIYHLKSRH PEQYAEYEKD
     TGAAAAAKRK VPPSTPTPSV ADFLEKAKKF ANDSAKTKGI TKKIMEFIAL DDQAFSVVED
     VGFRRLIDYI EPRYIMPSRR YFTDVCLPEM YNVISTHVHE LLATDIAALS FTTDIWSSDV
     SPTSVLSLTA QWIDTDFKLQ KVVLHSQELR GSHTATAISE AFANMFDTWR IDRSKVHVVV
     SDNARNMAEA MGDSDLKGIQ CMAHTIQLAV NEGVMSQRSI ADVIAIGRKI VGHFNHSPLA
     YARLQSIQEQ FALPTKRLQQ DVSTRWNSTY YMLESLFAQK RILAAYTADY DLPATFTAHQ
     WVVIENVLSL LAPFEQLTKE ISSSEASVAD VIPFLAALKR LLNKEAEKDN GVKTTKSTLL
     EAVHTRFIQA ASEPLYCIAT VLDPRYKEHY LDVGTKQHTR EIIQAELDSG KPLGDGQGMH
     CAGDGGDSAE RKRSRTDEPR TASLSDMFDE ILRENNPNAR QRTSSTTQQL DGYLSEVPIP
     RSNNPLEYWR TNQGRFPDLA QMARRYLSAP CTSTDSERLF SAASHIIDEK RTRLECGKAE
     KLLFIKKNLP LFLNKFPISK PQLAEQWVRS LGRKNFVPTT NSCLCSDHFL PDCFRDYNGK
     QFLREDAVPT IFSHSAKEGA DGTKIELRKN RGGLGTKEES RSGSISDGGK QQFPKERRQT
     TRDTGQKGKS GNDAYKRRGG AKVSSSDRQV MTAKSKVYDS RGLLISCGRD LCDCLDVDCM
     GCFYPCPECS SRKCGVECRC DRKWLYEQVE VEGGEIIRNK FAS
//