ID   A0A2D0Q7T4_ICTPU        Unreviewed;       688 AA.
AC   A0A2D0Q7T4;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2023, sequence version 2.
DT   27-MAR-2024, entry version 32.
DE   SubName: Full=Protein CBFA2T3 isoform X1 {ECO:0000313|RefSeq:XP_017314748.2};
GN   Name=cbfa2t3 {ECO:0000313|RefSeq:XP_017314748.2};
OS   Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC   Ictaluridae; Ictalurus.
OX   NCBI_TaxID=7998 {ECO:0000313|RefSeq:XP_017314748.2};
RN   [1] {ECO:0000313|RefSeq:XP_017314748.2}
RP   IDENTIFICATION.
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_017314748.2};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_017314748.2; XM_017459259.3.
DR   AlphaFoldDB; A0A2D0Q7T4; -.
DR   STRING; 7998.ENSIPUP00000035117; -.
DR   Ensembl; ENSIPUT00000036498; ENSIPUP00000035117; ENSIPUG00000023579.
DR   KEGG; ipu:108259624; -.
DR   OrthoDB; 5314634at2759; -.
DR   Proteomes; UP000221080; Chromosome 27.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003714; F:transcription corepressor activity; IEA:InterPro.
DR   GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR   Gene3D; 6.10.140.2220; -; 1.
DR   Gene3D; 6.10.250.230; -; 1.
DR   Gene3D; 1.20.120.1110; TAFH/NHR1 domain; 1.
DR   InterPro; IPR013289; CBFA2T1/2/3.
DR   InterPro; IPR014896; NHR2.
DR   InterPro; IPR037249; TAFH/NHR1_dom_sf.
DR   InterPro; IPR003894; TAFH_NHR1.
DR   InterPro; IPR002893; Znf_MYND.
DR   PANTHER; PTHR10379; MTG8 ETO EIGHT TWENTY ONE PROTEIN; 1.
DR   PANTHER; PTHR10379:SF6; PROTEIN CBFA2T3; 1.
DR   Pfam; PF08788; NHR2; 1.
DR   Pfam; PF07531; TAFH; 1.
DR   Pfam; PF01753; zf-MYND; 1.
DR   PRINTS; PR01875; ETOFAMILY.
DR   SMART; SM00549; TAFH; 1.
DR   SUPFAM; SSF144232; HIT/MYND zinc finger-like; 1.
DR   SUPFAM; SSF158553; TAFH domain-like; 1.
DR   PROSITE; PS51119; TAFH; 1.
DR   PROSITE; PS01360; ZF_MYND_1; 1.
DR   PROSITE; PS50865; ZF_MYND_2; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Repressor {ECO:0000256|ARBA:ARBA00022491};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00134}.
FT   DOMAIN          163..258
FT                   /note="TAFH"
FT                   /evidence="ECO:0000259|PROSITE:PS51119"
FT   DOMAIN          564..600
FT                   /note="MYND-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50865"
FT   REGION          1..24
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          43..156
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          313..349
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          610..688
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          503..545
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        106..155
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        610..646
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        661..688
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   688 AA;  75271 MW;  E394ABFA36893B67 CRC64;
     MYEMTSALHR DRYKRSGSRK HSSASASSFS QLLMSNRVAT VMLTSPRAAS DKHHVHQPLS
     TQTQRRRHAG SAETKVGTMP DSPADVKTQP RSTPPTMPPP PPAVSQAANR NASFTPTTML
     NGSSHSPTAL NGAPSTPNGF SNGPAGSSTA ALPTQQLPPA CGARQLCKLK RFLTTLQQFG
     NDISPEIGER VRSLVLGLVN STLTIEEFHG KLQEATNFPL RPFVIPFLKA NLPLLQRELL
     HCARLAKQTP AQYLAQHEQL LLDANANSPL DSSEILLELN EHGKRRTPDR TKEAGGERDA
     LHTEHMAKRP CTVSPSQRFS PSSGIAAHAP PNGLPTHPPN GLAHPSAPGP QQYRLEDMAM
     AHHYRDAYRH GEHRDSRERH RQTAVHGARQ EEVIDHRLTD REWAEEWKHL DNLLNCIMDM
     VEKTRRSLTV LRRCQEADRE EMNHWIRRYS DVEDMKKDIH RDFLHRPPSG YLPEEIWRKA
     GAPSIPLSPA IKQLHNKQEE AVNEVKRQAM SELQKAVSDA ERKAHEMISA ERSKMERALA
     EAKRQASEDA LSVINQQEDS SESCWNCGRK ASETCSGCNT ARYCGSFCQH KDWEKHHHVC
     GQTLQGLPGG SSVPLGTPSS SSSSSSSSSS SSSSSAPPTH SDSTAPGPLS LVGHAGGGGS
     PKDSSASSSS VSRSTTPATP ALLDSSSR
//