ID   A0A2D0Q8C4_ICTPU        Unreviewed;       472 AA.
AC   A0A2D0Q8C4;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=Keratin-like protein KRT222 {ECO:0000313|RefSeq:XP_017314547.1};
GN   Name=krt222 {ECO:0000313|RefSeq:XP_017314547.1};
OS   Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC   Ictaluridae; Ictalurus.
OX   NCBI_TaxID=7998 {ECO:0000313|RefSeq:XP_017314547.1};
RN   [1] {ECO:0000313|RefSeq:XP_017314547.1}
RP   IDENTIFICATION.
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_017314547.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the intermediate filament family.
CC       {ECO:0000256|RuleBase:RU000685}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   RefSeq; XP_017314547.1; XM_017459058.3.
DR   AlphaFoldDB; A0A2D0Q8C4; -.
DR   STRING; 7998.ENSIPUP00000013153; -.
DR   Ensembl; ENSIPUT00000013700; ENSIPUP00000013153; ENSIPUG00000008981.
DR   GeneID; 108259506; -.
DR   KEGG; ipu:108259506; -.
DR   CTD; 125113; -.
DR   OMA; QIASWGV; -.
DR   OrthoDB; 4111230at2759; -.
DR   Proteomes; UP000221080; Chromosome 27.
DR   GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.5.170; -; 1.
DR   InterPro; IPR018039; IF_conserved.
DR   InterPro; IPR039008; IF_rod_dom.
DR   PANTHER; PTHR47082; KERATIN-LIKE PROTEIN KRT222; 1.
DR   PANTHER; PTHR47082:SF1; KERATIN-LIKE PROTEIN KRT222; 1.
DR   Pfam; PF00038; Filament; 2.
DR   SMART; SM01391; Filament; 1.
DR   SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 1.
DR   PROSITE; PS00226; IF_ROD_1; 1.
DR   PROSITE; PS51842; IF_ROD_2; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW   ECO:0000256|RuleBase:RU000685}.
FT   DOMAIN          203..316
FT                   /note="IF rod"
FT                   /evidence="ECO:0000259|PROSITE:PS51842"
FT   REGION          170..211
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          58..127
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          281..315
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   472 AA;  54050 MW;  2FD11478E6F983F2 CRC64;
     MMEVCEGQQE VLRDLNKRLS GFLENAAQLQ KINLNLQEEL TAWTPTPERD WSWEERMVEE
     LRAQISRMLM ENAELALRSD RIKSTVHHLQ SRCELEQKLR LRLEQLIPDL RQKRMNLERD
     NTLLEEQLHT STLELHTIQD EQERELFVQL QQAAVGEDGR GMELRRFGPA HGDLGSAALT
     NRSPGFRPTA HARPGPNGDQ PPQVSHVSHR DEALREARAE LTEVRKQWHS LQVEVESLHA
     VERSLQSSLK HTQRQYSLQL RDLSRSVCEL EAELDGVREG LAAQKHHHNQ LLNTKMRLER
     EIATYRRLLE HEEGRFLSAD GQPRKLKPWK PSIQQNGVCN GFGNENEEKP ANQGPGLHRQ
     GSLVIFTEPI VSRNGEISTV KTQEIVEGNV VRESAEGHGR VETEKIDKVI KQWEGSVFQG
     NPKLRKKSVS LRFDLHMAAA DEGCAQSKQD SLPDVEVRLV MKRSRSIPSI TQ
//