ID A0A2D0Q8J1_ICTPU Unreviewed; 719 AA.
AC A0A2D0Q8J1;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Potassium voltage-gated channel subfamily C member 3a isoform X2 {ECO:0000313|RefSeq:XP_017314036.1};
GN Name=kcnc3a {ECO:0000313|RefSeq:XP_017314036.1};
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998 {ECO:0000313|RefSeq:XP_017314036.1};
RN [1] {ECO:0000313|RefSeq:XP_017314036.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_017314036.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR RefSeq; XP_017314036.1; XM_017458547.3.
DR AlphaFoldDB; A0A2D0Q8J1; -.
DR STRING; 7998.ENSIPUP00000020790; -.
DR GeneID; 108259249; -.
DR KEGG; ipu:108259249; -.
DR CTD; 559096; -.
DR OrthoDB; 1478695at2759; -.
DR Proteomes; UP000221080; Chromosome 2.
DR GO; GO:0008076; C:voltage-gated potassium channel complex; IEA:InterPro.
DR GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR CDD; cd18414; BTB_KCNC1_3; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 1.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR003968; K_chnl_volt-dep_Kv.
DR InterPro; IPR003974; K_chnl_volt-dep_Kv3.
DR InterPro; IPR021105; K_chnl_volt-dep_Kv3_ID.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR003131; T1-type_BTB.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR11537:SF282; POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY C MEMBER 3 ISOFORM X1; 1.
DR PANTHER; PTHR11537; VOLTAGE-GATED POTASSIUM CHANNEL; 1.
DR Pfam; PF02214; BTB_2; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR Pfam; PF11404; Potassium_chann; 1.
DR PRINTS; PR00169; KCHANNEL.
DR PRINTS; PR01491; KVCHANNEL.
DR PRINTS; PR01498; SHAWCHANNEL.
DR SMART; SM00225; BTB; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Potassium {ECO:0000256|ARBA:ARBA00022958};
KW Potassium channel {ECO:0000256|ARBA:ARBA00022826};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448};
KW Voltage-gated channel {ECO:0000256|ARBA:ARBA00022882}.
FT TRANSMEM 271..290
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 327..349
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 361..383
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 428..449
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 470..487
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 499..528
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 95..199
FT /note="BTB"
FT /evidence="ECO:0000259|SMART:SM00225"
FT REGION 207..230
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 719 AA; 79168 MW; FF8CD9C195C3B1A2 CRC64;
MFNHREPSNP AINVAILLKK RIVRFYGITL ENTFPGFLKN ILAPPPPRLS LPAPSTSSSM
LSSVCVSSFR GRKGGSKSCA KACASADMTC PSDSERIVIN CGGVRHETYR STLRTLPGTR
LSWLTEPDAC SNFDYDPKSD EFFFDRHPST FAFILNYYRT GKLHCPGDVC GPLFEEELAF
WGIDETDVEA CCWMNYRQHR DAEEALDSFE TPEPDAPEDE AAALAGGGGG GGADGDLKRL
CLHEDGGKKS WWSVWQPRVW ALFEDPYSSK YARYVAFGSL FFILISISTF CLETHEAFNT
IYNRTENVTV GNVTREELMF EVVTDSWLTY VEGVCVIWFT IEVFTRVIFC PDKAEFFKSS
LNIIDFVAIL PFYLEVALSG LSAKAAKDVL GFLRVVRFVR ILRIFKLTRH FVGLRVLGHT
LRASTNEFLL LIIFLALGVL IFATMIYYAE RIGADPGDPT ASAHTSFKNI PIGFWWAVVT
MTTLGYGDMY PETWSGMLVG ALCALAGVLT IAMPVPVIVN NFGMYYSLAM AKQKLPKKKN
KHIPRAPQPG SPNYCKPDAL AMATASPHRI MGNVLGGSIA GDCPLAQEEI IEINRADSKQ
NGDAANAALA NEDCPTIDQV LGPDDRSPAT GTGRYPHDRA CFLLSAGEFR TTDSNVRKGC
VVSCVSAGYE KSRSLNNISG MTGAPLRLTP ITPINSAPYE PYDSPGPLRR CRSPIPSIL
//
