ID   A0A2D0QFY0_ICTPU        Unreviewed;       665 AA.
AC   A0A2D0QFY0;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=TOX high mobility group box family member 4b isoform X1 {ECO:0000313|RefSeq:XP_017317207.1};
GN   Name=tox4b {ECO:0000313|RefSeq:XP_017317207.1};
OS   Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC   Ictaluridae; Ictalurus.
OX   NCBI_TaxID=7998 {ECO:0000313|RefSeq:XP_017317207.1};
RN   [1] {ECO:0000313|RefSeq:XP_017317207.1}
RP   IDENTIFICATION.
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_017317207.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   RefSeq; XP_017317207.1; XM_017461718.3.
DR   AlphaFoldDB; A0A2D0QFY0; -.
DR   STRING; 7998.ENSIPUP00000014069; -.
DR   Ensembl; ENSIPUT00000014664; ENSIPUP00000014069; ENSIPUG00000009590.
DR   GeneID; 108260964; -.
DR   KEGG; ipu:108260964; -.
DR   CTD; 100003353; -.
DR   OrthoDB; 4252846at2759; -.
DR   Proteomes; UP000221080; Chromosome 29.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   CDD; cd21995; HMG-box_TOX-like; 1.
DR   Gene3D; 1.10.30.10; High mobility group box domain; 1.
DR   InterPro; IPR009071; HMG_box_dom.
DR   InterPro; IPR036910; HMG_box_dom_sf.
DR   PANTHER; PTHR45781; AGAP000281-PA; 1.
DR   PANTHER; PTHR45781:SF6; TOX HIGH MOBILITY GROUP BOX FAMILY MEMBER 4; 1.
DR   Pfam; PF00505; HMG_box; 1.
DR   PRINTS; PR00886; HIGHMOBLTY12.
DR   SMART; SM00398; HMG; 1.
DR   SUPFAM; SSF47095; HMG-box; 1.
DR   PROSITE; PS50118; HMG_BOX_2; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00267};
KW   Nucleus {ECO:0000256|PROSITE-ProRule:PRU00267}.
FT   DOMAIN          313..381
FT                   /note="HMG box"
FT                   /evidence="ECO:0000259|PROSITE:PS50118"
FT   DNA_BIND        313..381
FT                   /note="HMG box"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT   REGION          225..245
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          294..315
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          396..426
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          452..474
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        400..420
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   665 AA;  69582 MW;  EE8937600B203E06 CRC64;
     MDLNFYSDLT DETGQTGDPE FLDAQAFNGF DPVPKFPGGS DNFLPISGEG HPFLSSSEVP
     LHSTYSLQIQ DAETFHTPSL GDEEFEIPPI SLVPDSALSV SDVVSHFGEL GDGGSAPVVP
     GNAVVQGDDP SFASTFVNPT TQGLEHLSLM TQQGGGPMLG STLGMDLGHP MGSQFSSSSP
     MTIDVPLPDM NHGLLGHNPL TTIDQSELSA QLGLSLGGGA ILTRAHSPDQ PLSATGSPSE
     SLQDDDMDDF RRSVLVESPV SLSVSPGVIS LSPALSEQPA ASVSSAPPAL ARKAVGVGGG
     AKKGKKKKDP NEPQKPVSAY ALFFRDTQAA IKGQNPNATF GEVSKIVASM WDSLGEEQKQ
     VYKRKTEAAK KEYLKALAAY RASQLSQPTI EVLDTAPSPP AAPIVTPAPE APPPQPTPTR
     SSRIPVHAPD NNTITNICTS NIIIDLPQVT TRSRTGAHKP PASSAPPTAP TPTLPMVTKI
     IIPKLPSARQ PPPLQQMQNT PPPPRLQQMV HSVAPPPLQA KPRGGGPVGQ ATATVTATPP
     PPLQIKIVPA PAQADVATPI IVTSTTEAPT DPAATAMEVE VVQPATIVTT EAEEGMEVEL
     NSSPAHEVAP PAGPVVCVRA GCNNLPVESK DWDREYCSNE CVATHCRDVF MAWCAIRGQN
     STTVT
//