UniProt: A0A2D0QN48

Database: UniProt
Entry: A0A2D0QN48_ICTPU

LinkDB:  A0A2D0QN48_ICTPU 
Original site:  A0A2D0QN48_ICTPU

All links

Ontology (3)   
   GO (3)   
Gene (4)   
   KEGG GENES (1)   
   ENSEMBL-UP (3)   
Protein sequence (1)   
   RefSeq(pep) (1)   
Protein domain (34)   
   InterPro (19)   
   Pfam (8)   
   PROSITE (3)   
   SMART (4)   
All databases (42)   

Download RDF

ID   A0A2D0QN48_ICTPU        Unreviewed;      2112 AA.
AC   A0A2D0QN48;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   22-FEB-2023, sequence version 2.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=Uncharacterized protein pks1 {ECO:0000313|RefSeq:XP_017318885.2};
GN   Name=pks1 {ECO:0000313|RefSeq:XP_017318885.2};
OS   Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC   Ictaluridae; Ictalurus.
OX   NCBI_TaxID=7998 {ECO:0000313|RefSeq:XP_017318885.2};
RN   [1] {ECO:0000313|RefSeq:XP_017318885.2}
RP   IDENTIFICATION.
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_017318885.2};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=holo-[ACP] + malonyl-CoA = CoA + malonyl-[ACP];
CC         Xref=Rhea:RHEA:41792, Rhea:RHEA-COMP:9623, Rhea:RHEA-COMP:9685,
CC         ChEBI:CHEBI:57287, ChEBI:CHEBI:57384, ChEBI:CHEBI:64479,
CC         ChEBI:CHEBI:78449; EC=2.3.1.39;
CC         Evidence={ECO:0000256|ARBA:ARBA00023404};
CC       PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:41793;
CC         Evidence={ECO:0000256|ARBA:ARBA00023404};
CC   -!- PATHWAY: Lipid metabolism; fatty acid biosynthesis.
CC       {ECO:0000256|ARBA:ARBA00005194}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   RefSeq; XP_017318885.2; XM_017463396.2.
DR   STRING; 7998.ENSIPUP00000019141; -.
DR   Ensembl; ENSIPUT00000019957; ENSIPUP00000019141; ENSIPUG00000012989.
DR   KEGG; ipu:108263015; -.
DR   OrthoDB; 5396558at2759; -.
DR   UniPathway; UPA00094; -.
DR   Proteomes; UP000221080; Chromosome 1.
DR   GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR   GO; GO:0004314; F:[acyl-carrier-protein] S-malonyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-UniPathway.
DR   CDD; cd05274; KR_FAS_SDR_x; 1.
DR   CDD; cd00833; PKS; 1.
DR   Gene3D; 3.30.70.3290; -; 1.
DR   Gene3D; 3.40.47.10; -; 1.
DR   Gene3D; 1.10.1200.10; ACP-like; 1.
DR   Gene3D; 3.30.70.250; Malonyl-CoA ACP transacylase, ACP-binding; 1.
DR   Gene3D; 3.40.366.10; Malonyl-Coenzyme A Acyl Carrier Protein, domain 2; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   Gene3D; 3.10.129.110; Polyketide synthase dehydratase; 1.
DR   InterPro; IPR001227; Ac_transferase_dom_sf.
DR   InterPro; IPR036736; ACP-like_sf.
DR   InterPro; IPR014043; Acyl_transferase.
DR   InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR018201; Ketoacyl_synth_AS.
DR   InterPro; IPR014031; Ketoacyl_synth_C.
DR   InterPro; IPR014030; Ketoacyl_synth_N.
DR   InterPro; IPR016036; Malonyl_transacylase_ACP-bd.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR032821; PKS_assoc.
DR   InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR   InterPro; IPR042104; PKS_dehydratase_sf.
DR   InterPro; IPR020807; PKS_DH.
DR   InterPro; IPR049551; PKS_DH_C.
DR   InterPro; IPR049552; PKS_DH_N.
DR   InterPro; IPR013968; PKS_KR.
DR   InterPro; IPR009081; PP-bd_ACP.
DR   InterPro; IPR016039; Thiolase-like.
DR   PANTHER; PTHR45681:SF6; CARRIER DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR45681; POLYKETIDE SYNTHASE 44-RELATED; 1.
DR   Pfam; PF00698; Acyl_transf_1; 1.
DR   Pfam; PF16197; KAsynt_C_assoc; 1.
DR   Pfam; PF00109; ketoacyl-synt; 1.
DR   Pfam; PF02801; Ketoacyl-synt_C; 1.
DR   Pfam; PF08659; KR; 1.
DR   Pfam; PF21089; PKS_DH_N; 1.
DR   Pfam; PF00550; PP-binding; 1.
DR   Pfam; PF14765; PS-DH; 1.
DR   SMART; SM00827; PKS_AT; 1.
DR   SMART; SM00826; PKS_DH; 1.
DR   SMART; SM00822; PKS_KR; 1.
DR   SMART; SM00825; PKS_KS; 1.
DR   SUPFAM; SSF47336; ACP-like; 1.
DR   SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   SUPFAM; SSF55048; Probable ACP-binding domain of malonyl-CoA ACP transacylase; 1.
DR   SUPFAM; SSF53901; Thiolase-like; 1.
DR   PROSITE; PS50075; CARRIER; 1.
DR   PROSITE; PS00606; KS3_1; 1.
DR   PROSITE; PS52004; KS3_2; 1.
PE   4: Predicted;
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          40..466
FT                   /note="Ketosynthase family 3 (KS3)"
FT                   /evidence="ECO:0000259|PROSITE:PS52004"
FT   DOMAIN          2034..2109
FT                   /note="Carrier"
FT                   /evidence="ECO:0000259|PROSITE:PS50075"
SQ   SEQUENCE   2112 AA;  234268 MW;  BD50199E23756829 CRC64;
     MKNLHVTQYP SLERDFKQFS LMRKLYKGPG IIVDDANSMD EDIAVVGIGC SFPGGEGLDN
     FWKVLIDGKN CTADIPEQRF NVTQWYNPDD TILGKIQTTK AAFIDGFNEF DHRFFGISEA
     EANFMDPQQK LLLQCSYRAL EDSGIPMEKV SGSRTGVYIG LMNRDYETLL NNSPSTITHY
     NGTGTAMSIA ANRISYTFNL TGPSFAIDSA CSSSLVAVHA ACQAIRQGDC EMALCGGVSC
     ILEPRVFVAL SKAKMISPEG TSKPFSKRAN GYGRGEGCGI VLLKTLKKAL QDFDHIWGIL
     CKTAVNQDGH TVSPITKPSM VQQEELLNRI YSTGTYLSDI QYVEAHGTGT PVGDSVEADS
     ISKVIAKARP PEVGPLLIGS VKSNIGHTES AAGVAGLIKV LLMMKHETIV PSVFYSEESS
     SIDVQALNLK IPTKAETWHY TGSMERVAGI NSFGFGGTNA HAIIREYKDA TSSNLERFGS
     RKLFPLSAAT SKSLEMCIAD TYQRISTENK VDLTTLLYTS ACRRSHMKHK YRKVYVTTSL
     LDLEEQLMTS LNTPLGAIKS DPKVVFVFCG NGVTYRGMCK QLLKEEPVFR EKIKEVENYF
     QNYRGTSILQ KIASSYDNDD FSKPDIVQPL LFATQVATVH LLKHWGIRPT AVLGHSVGEV
     AAAHCSGLLS LEEAVKVIYY RSVLQSKVTG GKMLVVGNIT VSDILKILPA YTGKVCLAAL
     NSPLSCVLSG EKDAIESVHQ MLKNSFKAKN MFLHVLDVPA AYHSHMMDPV LTQIRDSIGS
     LNQHEMECEL FSTVTGRTCS LGDFVTGDYW ARNIRNPVAF EQAVRAVASN RKNIIFVEIG
     PRRALQRNIV ETLGNDTVVL SSIQPDKDQD ALLTVVSKLF ELGVNVDWDQ FYNGFQSPPA
     SYPVYQFDCP KNDVHFEEVR QGNEVMSLCP HPLIIPHKHN NRMFKCNLSV EATPYLWEHK
     SNGIVIAPGA LYTELALASV MESIIPKIPL ASLQLTINFQ NLLVLSKSSH CLKVQLEPHE
     DNTLFQIQSS ATTHASGTIA YRKGSAVTNH QDILLDIISN RCPSVIPGDQ VYVTLKKAGF
     EYGPIFQQLG DIQYGEDFKE AVANVRIPDQ LLTQLYKYCL HPVVLDYFLQ MTSVLALSNS
     TIKHGFPSEI GSMVITAPLC EEMVIYMRLT QEMPEYFEVC GCFTDRKGHA LIELKDVRIT
     LVGDSAKVTD FYFFHNEKFA VPAITSIHSK PKAVVFEDTL GIANALKTYL HPSSVFFSPA
     DVGLSSLQVP DFLLHLDHHT ADMEKVLFIW SCQNLSFLKT QIVLEQLADI CELYRHIVLT
     LRKCKHLRTL HVITYRSSDS TVDHISPGFV LSGMTRACAA ELSEISFQLI DLATVSSEDI
     KALGYIICSY KSHEYPEVMI RQGQVQSTVI TRTALNKIDK GINSSWSERF TLQTANPYEM
     SCLSAIPTND VLDFTDGKNV EVQLYKICMH SSDYFPVSLS DLKFGQTLYW NKHTSQNHKL
     LALDFSGTVT AVGKDVKKLK VGDHIVSCYP TVAASKVTLP EDACYKTKRL QFLKDTPCVS
     YIILAWEILH SALPKVKQNK TLGIFSTTPD SALMKMLTVT ANKSGWNVVT EMELNALGQC
     LDQCPVFVLL PPYDQACLAQ LSSEANAKHI FLVCDSNSPP TNILSNNSEN MCFHFVKVCN
     IFQKSYLKTQ SSDVYRWLKM MHLDSKFLSL QSKAFHPSKS ETENVGSYFN AKTVSLIVLD
     NSGSMAGRSQ ICLQPRPMQL FSKTAVYIVS GGLSGLGRET VKFISHWGGK CIATLSRSAP
     SEETQLHINN LKKRYGARII TLQCDVSVSD EVLEAITVIG QKFPSCPIKG IFHSAAVLHD
     GLLETLNKSL FEKVLRPKVS GALNLHYATL NSKLDYFVCY SSISSFIGNA SQANYAAANS
     FLDTLCHYRR NIGLAAQSIN WGPLKLGLLF NKADFQKFLE TKGLMTMEVP EIHEALKHCL
     LENKPQQVVC KFNFRNLRNN VLSQNASLKV RLAALIEKEF EVKTVNESRN DLQSSFDDYI
     RSMVGDICNV DADEFEPETC LAALGIDSML AMTLQNQMFQ DIGVNIPLVS LLDPNITLNS
     LAILLKESND DK
//

DBGET integrated database retrieval system