ID   A0A2D0QNP4_ICTPU        Unreviewed;       703 AA.
AC   A0A2D0QNP4;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=Mitochondrial antiviral-signaling protein {ECO:0000313|RefSeq:XP_017319351.1};
GN   Name=mavs {ECO:0000313|RefSeq:XP_017319351.1};
OS   Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC   Ictaluridae; Ictalurus.
OX   NCBI_TaxID=7998 {ECO:0000313|RefSeq:XP_017319351.1};
RN   [1] {ECO:0000313|RefSeq:XP_017319351.1}
RP   IDENTIFICATION.
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_017319351.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_017319351.1; XM_017463862.3.
DR   AlphaFoldDB; A0A2D0QNP4; -.
DR   STRING; 7998.ENSIPUP00000008988; -.
DR   Ensembl; ENSIPUT00000009381; ENSIPUP00000008988; ENSIPUG00000006147.
DR   GeneID; 108263240; -.
DR   KEGG; ipu:108263240; -.
DR   CTD; 57506; -.
DR   OMA; NQHDQTE; -.
DR   OrthoDB; 5358122at2759; -.
DR   Proteomes; UP000221080; Chromosome 3.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0002376; P:immune system process; IEA:UniProt.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProt.
DR   Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR   InterPro; IPR031964; CARD_dom.
DR   InterPro; IPR011029; DEATH-like_dom_sf.
DR   Pfam; PF16739; CARD_2; 1.
DR   SUPFAM; SSF47986; DEATH domain; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        685..702
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          7..93
FT                   /note="Caspase recruitment"
FT                   /evidence="ECO:0000259|Pfam:PF16739"
FT   REGION          157..191
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          213..266
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          418..437
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        157..186
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        237..266
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   703 AA;  74232 MW;  1474A6535764B31D CRC64;
     MAYAGDRLYK EVIRKMMGDL ATKVRVREII AYLPCLTLSD REEIEAKRET HGNYNAMMVL
     LDNLQRRENW PDQFISALRT CEQSALANKI SEEYDKIRGI HTQRRAAAAA SAPVLPAVAS
     VSPAAPPAPA PAPAAAVPSP ALAPAEASAT VTTATIHSVP RSTPPLLTTS VEASAQPATP
     LINSRPEPYS TIAAPASTEA PALVSAPDAL VRAPPESAQP AEPPLSVLAS DARPPSPVSA
     PTLTASIGQS EVPGTSAPIN SSPESCSNIA SPAMTEAPAL VSALENSVQP HRKPAHPAEP
     PLLVLVPHAI PPSPVSAPEV TPSVGQREVP VDARKTPTLD ISGGLTNTAL SGPSSITACT
     LSTSPQKSNV PVAVVESSSY VKHPIQDTSP HGTVLGQDSQ NNPTITQVVH TAVSPNCQTQ
     ETSQRTAQAT PSASTDAVAG GLSNLAAENE ENFSKPDVLR GEEPFSVSSD RLQISHMTME
     RSPFQPQAMP NTYRAEEPVD ESVSVTTDDL MFSSSTTAVL SQHVSDPVVP VQNSAPRPLE
     NGFQEVPCPN QPVEDHYESI CQSLQTRVHI VKVSEGRSVQ NLSGQPPSMV RPTTARLNDN
     GETKSIVQSI SKDQPSCHIQ DTSQCIQENN ASEQASPSAG LTTYAYTGTV QKSELKASGQ
     INVPHSEQRE ESQGVLQRFQ SNSHLIVAAA VCMAAVFVAW RLK
//