ID A0A2D0QR58_ICTPU Unreviewed; 518 AA.
AC A0A2D0QR58;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Sprouty-related, EVH1 domain-containing protein 3 {ECO:0000313|RefSeq:XP_017320784.1};
GN Name=spred3 {ECO:0000313|RefSeq:XP_017320784.1};
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998 {ECO:0000313|RefSeq:XP_017320784.1};
RN [1] {ECO:0000313|RefSeq:XP_017320784.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_017320784.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_017320784.1; XM_017465295.3.
DR AlphaFoldDB; A0A2D0QR58; -.
DR STRING; 7998.ENSIPUP00000000950; -.
DR Ensembl; ENSIPUT00000001011; ENSIPUP00000000950; ENSIPUG00000000681.
DR GeneID; 108264009; -.
DR KEGG; ipu:108264009; -.
DR CTD; 399473; -.
DR OMA; LPLHACH; -.
DR OrthoDB; 3031266at2759; -.
DR Proteomes; UP000221080; Chromosome 4.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0009966; P:regulation of signal transduction; IEA:InterPro.
DR CDD; cd10574; EVH1_SPRED-like; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR023337; KBD.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR041937; SPRE_EVH1.
DR InterPro; IPR007875; Sprouty.
DR InterPro; IPR000697; WH1/EVH1_dom.
DR PANTHER; PTHR11202:SF19; SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN 3; 1.
DR PANTHER; PTHR11202; SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN FAMILY MEMBER; 1.
DR Pfam; PF05210; Sprouty; 1.
DR Pfam; PF00568; WH1; 1.
DR SMART; SM00461; WH1; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS51488; KBD; 1.
DR PROSITE; PS51227; SPR; 1.
DR PROSITE; PS50229; WH1; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 476..497
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..113
FT /note="WH1"
FT /evidence="ECO:0000259|PROSITE:PS50229"
FT DOMAIN 236..302
FT /note="KBD"
FT /evidence="ECO:0000259|PROSITE:PS51488"
FT REGION 116..152
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 206..240
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 322..393
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 137..152
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 208..235
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 322..375
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 518 AA; 55231 MW; B80CD2D003F7E8C8 CRC64;
MEGDVRVRAV VMTRDDSSGG WVPLGGGGLS HVVICKGRSS ESHGQKEYVI RGERLRDRAP
VLECAIQKGL IYNKVNPIFH HWRVEERKFG LTFQSPADAI SFEKGLQIVL DKLDKGFDSP
SSSTPEEGDT EDDGQASHTG SESSSNSRKE MLPKPITIVT SESSATCFVH STAEEFGYGE
GHAITTQTPA QVHRRPCQHQ LSQVSAVLNP PAPPPPPPAP PTSPLAPPAS PPLSPLSPTM
SLLEEGDLRS IDPCKDLWGS RGYEDYRRAG ATRTKVGGLT GGVMVGGGPD KSELCVVHFE
KELAGVGTPG CEVAVMLDTK GSRRHSSSPT CMPNAISGAS PASGSPQETG KSSPSPCCIH
TSLATPRSRT RKRGGSGTSG GGEAISPDDD SPCPQGSSSC SSRCVYCRSV FSASENGRGR
CRDAPDPALH CLRQWTCVWC AESLLYHCMS DSEGEFWEPC SCEDSLGRRP HPLCCAGWMA
LLALSLFVPC MCCYLPLRAC LRCGERCGCC GGKHKAVR
//
