ID   A0A2D0QSC5_ICTPU        Unreviewed;       435 AA.
AC   A0A2D0QSC5;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   SubName: Full=Heat shock factor protein 4 {ECO:0000313|RefSeq:XP_047011056.1};
GN   Name=hsf4 {ECO:0000313|RefSeq:XP_047011056.1};
OS   Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC   Ictaluridae; Ictalurus.
OX   NCBI_TaxID=7998 {ECO:0000313|RefSeq:XP_047011056.1};
RN   [1] {ECO:0000313|RefSeq:XP_047011056.1}
RP   IDENTIFICATION.
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_047011056.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the HSF family. {ECO:0000256|ARBA:ARBA00006403,
CC       ECO:0000256|RuleBase:RU004020}.
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DR   RefSeq; XP_017321311.1; XM_017465822.1.
DR   RefSeq; XP_017321312.1; XM_017465823.1.
DR   RefSeq; XP_047011056.1; XM_047155100.2.
DR   AlphaFoldDB; A0A2D0QSC5; -.
DR   STRING; 7998.ENSIPUP00000006259; -.
DR   KEGG; ipu:124625954; -.
DR   Proteomes; UP000221080; Chromosome 4.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR000232; HSF_DNA-bd.
DR   InterPro; IPR027725; HSF_fam.
DR   InterPro; IPR010542; Vert_HSTF_C.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR10015:SF213; HEAT SHOCK FACTOR PROTEIN 4; 1.
DR   PANTHER; PTHR10015; HEAT SHOCK TRANSCRIPTION FACTOR; 1.
DR   Pfam; PF00447; HSF_DNA-bind; 1.
DR   Pfam; PF06546; Vert_HS_TF; 1.
DR   PRINTS; PR00056; HSFDOMAIN.
DR   SMART; SM00415; HSF; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS00434; HSF_DOMAIN; 1.
PE   3: Inferred from homology;
KW   Activator {ECO:0000256|ARBA:ARBA00023159};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Stress response {ECO:0000313|RefSeq:XP_047011056.1}.
SQ   SEQUENCE   435 AA;  49311 MW;  4DD57CFC182C153A CRC64;
     MQESPGSIGV DGGYANNVPA FLTKLWTLVE DPETNHLICW STTGTSFHVF DQGRFAKEVL
     PKYFKHNNMA SFVRQLNMYG FRKVVNIEQS GLVKPERDDT EFQHLYFLQG HEHLLEHIKR
     KVSIVKSEET KFRQEDLSKL LYEVQVLRSQ QENMECQMQD MKQQNEVLWR EVVSLRQNHT
     QQQKVMNKLI QFLFSQMQAS PPSTVGMKRK LPLMLDDGAT TPPTSKLSHS HSMESIQEAF
     YIQSPSTEAA SCSTSNTMTV GPIIADVTDM SQPSAMAIQM EEARERCPMI IKEEPVSPGV
     HRWSEDMSCG VCTEPPVLPL AMVQSVLEGR GSGPGERRAK RTIDKPEPSE AVENVDMSFE
     ELQLLLRNHQ QSIESSSANV DAFTFSMPIN EWNFTEMDPN LKSELSNILV PAAMSQYMFQ
     CQEGEVCNAN GCEEQ
//