ID A0A2D0QSI3_ICTPU Unreviewed; 320 AA.
AC A0A2D0QSI3;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Forkhead box protein E1 {ECO:0000313|RefSeq:XP_017320445.1};
GN Name=foxe1 {ECO:0000313|RefSeq:XP_017320445.1};
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998 {ECO:0000313|RefSeq:XP_017320445.1};
RN [1] {ECO:0000313|RefSeq:XP_017320445.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_017320445.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00089}.
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DR RefSeq; XP_017320445.1; XM_017464956.3.
DR AlphaFoldDB; A0A2D0QSI3; -.
DR STRING; 7998.ENSIPUP00000002453; -.
DR GeneID; 108263799; -.
DR KEGG; ipu:108263799; -.
DR CTD; 2304; -.
DR OrthoDB; 5385885at2759; -.
DR Proteomes; UP000221080; Chromosome 3.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR CDD; cd20019; FH_FOXE; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR001766; Fork_head_dom.
DR InterPro; IPR018122; TF_fork_head_CS_1.
DR InterPro; IPR030456; TF_fork_head_CS_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11829; FORKHEAD BOX PROTEIN; 1.
DR PANTHER; PTHR11829:SF392; FORKHEAD BOX PROTEIN E1; 1.
DR Pfam; PF00250; Forkhead; 1.
DR PRINTS; PR00053; FORKHEAD.
DR SMART; SM00339; FH; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00657; FORK_HEAD_1; 1.
DR PROSITE; PS00658; FORK_HEAD_2; 1.
DR PROSITE; PS50039; FORK_HEAD_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00089}; Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089}.
FT DOMAIN 40..134
FT /note="Fork-head"
FT /evidence="ECO:0000259|PROSITE:PS50039"
FT DNA_BIND 40..134
FT /note="Fork-head"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT REGION 1..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 320 AA; 35206 MW; 22A0ECC69FB4BD89 CRC64;
MPVVKAEDEA PAQTAVETTD SQNADPPKGR RRKRPLQRGK PPYSYIALIS MAIASSPDRK
LTLGGIYKFI TDRFPFYRDN SKKWQNSIRH NLTLNDCFVK IPREPGRPGK GNYWSLDPNA
EDMFESGSFL RRRKRFKRCD FNTYCTSSST YHHDSPIFSP VQIASSVYGS VYPTYAPQIS
PPYYPPSTTP FGSSQSRVFS INTIIGSGGL VHSPPETPPA QPSCRNFTQD GGGSCSLNSN
HIAFSYPNTG NHGYGQAAQG MFTHNGTQNY IPSGRLGVTG SSPITTDVAN DPYIHNSGGT
GGYMRPVTYP SCMDRFVSAI
//
