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Database: UniProt
Entry: A0A2D0QT54_ICTPU
LinkDB: A0A2D0QT54_ICTPU
Original site: A0A2D0QT54_ICTPU 
ID   A0A2D0QT54_ICTPU        Unreviewed;       460 AA.
AC   A0A2D0QT54;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   16-OCT-2019, entry version 12.
DE   SubName: Full=Friend leukemia integration 1 transcription factor isoform X1 {ECO:0000313|RefSeq:XP_017321484.1};
GN   Name=fli1 {ECO:0000313|RefSeq:XP_017321484.1};
OS   Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC   Ictaluridae; Ictalurus.
OX   NCBI_TaxID=7998 {ECO:0000313|Proteomes:UP000221080, ECO:0000313|RefSeq:XP_017321484.1};
RN   [1] {ECO:0000313|RefSeq:XP_017321484.1}
RP   IDENTIFICATION.
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_017321484.1};
RG   RefSeq;
RL   Submitted (NOV-2017) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004019,
CC       ECO:0000256|SAAS:SAAS00594387}.
CC   -!- SIMILARITY: Belongs to the ETS family.
CC       {ECO:0000256|RuleBase:RU004019, ECO:0000256|SAAS:SAAS00594391}.
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DR   RefSeq; XP_017321484.1; XM_017465995.1.
DR   GeneID; 108264452; -.
DR   KEGG; ipu:108264452; -.
DR   CTD; 2313; -.
DR   KO; K09436; -.
DR   OMA; GWGSNMN; -.
DR   OrthoDB; 1113327at2759; -.
DR   Proteomes; UP000221080; Genome assembly.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR   GO; GO:0051091; P:positive regulation of DNA-binding transcription factor activity; IEA:Ensembl.
DR   CDD; cd08541; SAM_PNT-FLI-1; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 1.10.150.50; -; 1.
DR   InterPro; IPR000418; Ets_dom.
DR   InterPro; IPR035575; Fli-1.
DR   InterPro; IPR003118; Pointed_dom.
DR   InterPro; IPR013761; SAM/pointed_sf.
DR   InterPro; IPR035573; SAM_PNT-FLI-1.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11849:SF161; PTHR11849:SF161; 1.
DR   Pfam; PF00178; Ets; 1.
DR   Pfam; PF02198; SAM_PNT; 1.
DR   PRINTS; PR00454; ETSDOMAIN.
DR   SMART; SM00413; ETS; 1.
DR   SMART; SM00251; SAM_PNT; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF47769; SSF47769; 1.
DR   PROSITE; PS00345; ETS_DOMAIN_1; 1.
DR   PROSITE; PS00346; ETS_DOMAIN_2; 1.
DR   PROSITE; PS50061; ETS_DOMAIN_3; 1.
DR   PROSITE; PS51433; PNT; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000221080};
KW   DNA-binding {ECO:0000256|RuleBase:RU004019,
KW   ECO:0000256|SAAS:SAAS00594397};
KW   Nucleus {ECO:0000256|RuleBase:RU004019,
KW   ECO:0000256|SAAS:SAAS00594400};
KW   Reference proteome {ECO:0000313|Proteomes:UP000221080}.
FT   DOMAIN      120    206       PNT. {ECO:0000259|PROSITE:PS51433}.
FT   DOMAIN      289    369       ETS. {ECO:0000259|PROSITE:PS50061}.
FT   REGION       37     63       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      207    272       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS     41     63       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS    235    272       Polar. {ECO:0000256|SAM:MobiDB-lite}.
SQ   SEQUENCE   460 AA;  51738 MW;  E2B138C0B5609BCF CRC64;
     MTMFQTVPDT SSYVKEALSV VSEDQSLFEP PYAAAAPLPK TDMTASSTQD YGQQHKINPI
     PPQQEWINQP GRINVKREYD HLNGTRESPV DCSVGKCNKL VSSSDTSQMG YGGYMDEKSA
     PPPNMTTNER RVIVPADPSL WSPDHVRQWL DWAVKEYGLL EIDTAMFQNT DGKELCKMSK
     EDFLRLTTVY NAEVLLSHLN YLRESSSSLS YNTPSHTDQS PRLAAKEDAS YDAVRRTGWS
     NNMHSGKGSP TVVSQNVSKS TEQTRPQPDP YQILGPTSSR LANPGSGQIQ LWQFLLELLS
     DSANAGCITW EGTNGEFKMT DPDEVARRWG ERKSKPNMNY DKLSRALRYY YDKNIMTKVH
     GKRYAYKFDF HGIAQALQPH PTEPSMYKYP SDLAYVPPYH AHQQKVNFVS PHPPSMPVTS
     SNFFGPSNPY WSSPTAGIYP SASVPRHPNS HMPSHLGSYY
//
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